ChemInform Abstract: A Simple, Mild, and Efficient Procedure for High-Yield Synthesis of Benzimidazoles Using Copper Triflate as Catalyst.

ChemInform ◽  
2010 ◽  
Vol 41 (24) ◽  
pp. no-no
Author(s):  
M. Adharvana Chari ◽  
P. Sadanandam ◽  
D. Shobha ◽  
K. Mukkanti
Keyword(s):  
High Yield ◽  
Efficient Procedure

High-yield purification of the complex-forming glycoprotein in urine from normal and abnormal subjects.

1989 ◽  
Vol 35 (4) ◽  
pp. 577-581 ◽  
Author(s):  
H Wakui ◽  
R Kobayashi ◽  
H Itoh ◽  
H Imai ◽  
Y Nakamoto ◽  
...  
Keyword(s):  
Biochemical Properties ◽  
High Yield ◽  
Gel Chromatography ◽  
Tubular Proteinuria ◽  
Charge Heterogeneity ◽  
Purification Method ◽  
Efficient Procedure ◽  
Renal Disorders ◽  
Special Collection ◽  
Urine Specimens

Abstract Ordinary methods for purification of complex-forming glycoprotein (protein HC) or alpha 1-microglobulin, a protein closely related to protein HC, require either large volumes of urine or special collection of urine specimens from patients with tubular proteinuria. Here we describe a fast, efficient procedure for isolating protein HC in high yield from urines from healthy and diseased subjects, with use of Cibacron blue, hydroxylapatite, and gel chromatography. Using this procedure, we also obtained a considerable amount of polymeric protein HC from the urine of a patient with chronic renal failure. The pattern of charge heterogeneity and immunoreactivity with anti-protein HC differed between the polymeric and monomeric forms of protein HC. We also observed a variability in charge heterogeneity of protein HC among patients with renal disorders. These results demonstrate that this purification method is useful for further studies to elucidate the biochemical properties of protein HC and its clinical significance in renal disorders.

A Facile and Efficient Procedure for Deprotection of 1,1-Diacetates Catalysed by H2NSO3H

2003 ◽  
Vol 2003 (1) ◽  
pp. 30-32 ◽  
Author(s):  
Tong-Shou Jin ◽  
Guang Sun, Yan–Wei Li ◽  
Tong-Shuang Li
Keyword(s):  
High Yield ◽  
Efficient Procedure

A rapid, efficient and high yield method of the deprotection of 1,1-diacetates is described which occurs under catalysis of H2NSO3H.

scholarly journals A Potentially Useful Procedure for Conversion of Ethers to Esters

2021 ◽  
Vol 3 (1) ◽  
Author(s):  
Li H ◽  
Mark Z ◽  
Graylion M ◽  
Shen T
Keyword(s):  
Building Blocks ◽  
Cyclic Ether ◽  
Gas Chromatography Mass Spectrometry ◽  
High Yield ◽  
Infrared Spectrometry ◽  
Cyclic Ethers ◽  
Efficient Procedure ◽  
Nuclear Magnetic Resonance Spectrometry ◽  
Magnetic Resonance Spectrometry ◽  
Reaction Processes

This communication reports a catalytic system for transformation of ethers into their corresponding esters, especially for cyclic ethers. This efficient procedure was developed as part of our efforts to synthesize nucleoside building blocks and their derivatives. Gas Chromatography-Mass Spectrometry (GC-MS) monitored the reaction processes, Nuclear Magnetic Resonance Spectrometry (NMR), and Infrared Spectrometry (IR) were used to verify the structure of the products. The conversions of Tetrahydrofuran (THF) and other cyclic ether into lactones were accomplished in high yield, over 95%. This approach could be extended too many types of ethers to produce directly corresponding esters simply. Four representatives of ethers were investigated. Cyclic ethers have the higher yields. Linear ethers gave lower yields. The reaction on methoxylcarbon or methyl ether carbon was not observed. The reacted catalyst can be reused over several times. For each reusing, only drops of sulfuric acid need to be added. Nevertheless, the asymmetric ethers selectivity needs to be addressed in future studies.

Efficient Procedure for High-Yield Synthesis of 4-Substituted 3,5-Dinitropyrazoles Using 4-Chloro-3,5-dinitropyrazole

Synthesis ◽  
2012 ◽  
Vol 44 (13) ◽  
pp. 2058-2064 ◽  
Author(s):  
Igor Dalinger ◽  
Irina Vatsadze ◽  
Tatyana Shkineva ◽  
Galina Popova ◽  
Svyatoslav Shevelev
Keyword(s):  
High Yield ◽  
Efficient Procedure

New Constrained Amines in a Bicyclo[2.2.1]Heptane Skeleton

2018 ◽  
Vol 69 (9) ◽  
pp. 2448-2453 ◽  
Author(s):  
Constantin I. Tanase ◽  
Constantin Draghici ◽  
Catalina Negut ◽  
Lucia Pintilie
Keyword(s):  
Click Chemistry ◽  
Selective Reduction ◽  
Optically Active ◽  
Pure Form ◽  
High Yield ◽  
Protecting Group ◽  
Efficient Procedure ◽  
Primary Hydroxyl ◽  
Selective Crystallization ◽  
Heterocyclic Bases

In this paper we present an efficient procedure for obtaining ether-protected bicyclo[2.2.1]heptane amines in six steps, from an optically active keto-alcohol norbornane compound, for building the heterocyclic bases of pyrimidine and purine constrained nucleosides. Trityl as protecting group makes it possible to isolate 5-endo-compounds in pure form by selective crystallization, and to isolate the intermediates in the next 3 steps of the reaction by crystallization. With TBDMS, all compounds were obtained as oil. The direct selective reduction of the keto-alcohol norbornane compound gave the pure 5-endo-diol 4d in high yield, which was then selectively protected at the primary hydroxyl with a trityl group; the next steps are similar for obtaining the trityl-protected bicyclo[2.2.1]heptane amine. The azide intermediates are valuable intermediates for click chemistry.

scholarly journals Novel and Efficient Procedure for the Preparation of Two Pyridine Dicarboxylic Acid Derivatives

2011 ◽  
Vol 8 (1) ◽  
pp. 449-452 ◽  
Author(s):  
G. U. Guoliang ◽  
L. U. Ming
Keyword(s):  
Green Chemistry ◽  
Dicarboxylic Acid ◽  
High Purity ◽  
High Yield ◽  
Efficient Procedure ◽  
Pyridine Dicarboxylic Acid ◽  
Vinyl Pyridine ◽  
Synthesis Procedure ◽  
New Strategies

New strategies for the synthesis of two pyridine dicarboxylic acid derivatives namely; 4-(2-(2,6-dicarboxypyridin-4-yl)vinyl)pyridine-2,6-dicarboxylic acid and 2,6-bis(2-(2,6–dicarboxy-pyridin-4-yl)vinyl)pyridine have been described. New oxidant used is a good example of green chemistry technology and the synthesis procedure harvest a high-purity product at a high yield.

A Rapid and Efficient Procedure for Deprotection of 1,1-diacetates Catalysed by Silica Sulfate

2005 ◽  
Vol 2005 (7) ◽  
pp. 438-439 ◽  
Author(s):  
Tong-Shou Jin ◽  
Ying Zhao ◽  
Li-Bin Liu ◽  
Tong-Shuang Li
Keyword(s):  
Environmentally Friendly ◽  
High Yield ◽  
Efficient Procedure

An efficient procedure for converting a number of 1,1-diacetates into the corresponding aldehydes was developed with silica sulfate as catalyst. The advantages of this procedure is its brevity, and high yield. It is environmentally friendly and the catalyst is also inexpensive and reusable.

ChemInform Abstract: Efficient Procedure for High-Yield Synthesis of 4-Substituted 3,5-Dinitropyrazoles Using 4-Chloro-3,5-dinitropyrazole.

ChemInform ◽  
2012 ◽  
Vol 43 (42) ◽  
pp. no-no
Author(s):  
Igor L. Dalinger ◽  
Irina A. Vatsadze ◽  
Tatyana K. Shkineva ◽  
Galina P. Popova ◽  
Svyatoslav A. Shevelev
Keyword(s):  
High Yield ◽  
Efficient Procedure

An efficient procedure for the TEMPO-catalyzed oxidation of alcohols to aldehydes and ketones using ferric chloride hexahydrate as terminal oxidant

2008 ◽  
Vol 86 (7) ◽  
pp. 720-725 ◽  
Author(s):  
R Senthil Kumar ◽  
K Karthikeyan ◽  
Paramasivan T Perumal
Keyword(s):  
Ferric Chloride ◽  
High Yield ◽  
Efficient Procedure ◽  
Chloride Hexahydrate ◽  
Oxidation Of Alcohols ◽  
Aldehydes And Ketones ◽  
Ferric Chloride Hexahydrate ◽  
Catalyzed Oxidation

A simple, efficient procedure for the oxidation of alcohols by catalytic 2,2,6,6-tetramethyl-piperidyl-1-oxy (TEMPO) was developed using FeCl3·6H2O as the terminal oxidant. The reaction gives high yield of the corresponding aldehydes and ketones with no over oxidation to the acid.Key words: oxidation, TEMPO, FeCl3·6H2O.

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