ChemInform Abstract: Fischerindoline, a Pyrroloindole Sesquiterpenoid Isolated from Neosartorya pseudofischeri, with in vitro Growth Inhibitory Activity in Human Cancer Cell Lines.

ChemInform ◽  
2013 ◽  
Vol 44 (52) ◽  
pp. no-no
Author(s):  
Marco Masi ◽  
Anna Andolfi ◽  
Veronique Mathieu ◽  
Angela Boari ◽  
Alessio Cimmino ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Inhibitory Activity ◽  
Human Cancer ◽  
In Vitro Growth ◽  
Human Cancer Cell ◽  
Human Cancer Cell Lines ◽  
Growth Inhibitory ◽  
Growth Inhibitory Activity

Fischerindoline, a pyrroloindole sesquiterpenoid isolated from Neosartorya pseudofischeri, with in vitro growth inhibitory activity in human cancer cell lines

Tetrahedron ◽  
2013 ◽  
Vol 69 (35) ◽  
pp. 7466-7470 ◽  
Author(s):  
Marco Masi ◽  
Anna Andolfi ◽  
Veronique Mathieu ◽  
Angela Boari ◽  
Alessio Cimmino ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Inhibitory Activity ◽  
Human Cancer ◽  
In Vitro Growth ◽  
Human Cancer Cell ◽  
Human Cancer Cell Lines ◽  
Growth Inhibitory ◽  
Growth Inhibitory Activity

Synthesis of C4-fluorinated solamins and their growth inhibitory activity against human cancer cell lines

2008 ◽  
Vol 18 (24) ◽  
pp. 6451-6453 ◽  
Author(s):  
Naoto Kojima ◽  
Hiromi Hayashi ◽  
Satoshi Suzuki ◽  
Hiroaki Tominaga ◽  
Naoyoshi Maezaki ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Inhibitory Activity ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Human Cancer Cell Lines ◽  
Growth Inhibitory ◽  
Growth Inhibitory Activity

scholarly journals Natural and Synthetic Furanones with Anticancer Activity

2016 ◽  
Vol 11 (10) ◽  
pp. 1934578X1601101
Author(s):  
Alessio Cimmino ◽  
Patrizia Scafato ◽  
Veronique Mathieu ◽  
Aude Ingels ◽  
Wanda D'Amico ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Inhibitory Activity ◽  
Cancer Cell Lines ◽  
Side Chain ◽  
In Vitro Growth ◽  
Growth Inhibitory ◽  
Growth Inhibitory Activity ◽  
Growth Activity

This paper describes the enantioselective synthesis of analogues of sapinofuranones A and B, namely 5-substitutes dihydro- and 5 H-furan-ones, and their in vitro growth inhibitory activity against six cancer cell lines in comparison with fungal furanones such as diplofuranone A, diplobifuranylones A and B, as well as ( S,S)-enantiomer of sapinofuranone B. The compounds under study displayed weak if any in vitro growth inhibitory activity against the analysed cancer cell lines. However, it seems that among dihydro- and 5 H-furan-ones bearing a 1-hydroxypentyl side chain, the stereochemistry of the furanone ring and that of hydroxylated methine could modify the in vitro growth activity of these compounds. The natural furanones that showed a different unsaturated chain at C-4 or rearranged into a dihydrofuran ring appeared to be inactive in terms of growth inhibitory activity, e.g. displaying growth inhibitory concentration at 50% (GI50) > 100 μM in all six cancer cell lines analysed.

Enantiomeric resolution of albendazole sulfoxide by semipreparative HPLC and in vitro study of growth inhibitory effects on human cancer cell lines

2012 ◽  
Vol 66 ◽  
pp. 100-108 ◽  
Author(s):  
Kátia Roberta A. Belaz ◽  
Marina Denadai ◽  
Ana Paula Almeida ◽  
Raquel T. Lima ◽  
M. Helena Vasconcelos ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
In Vitro Study ◽  
Human Cancer Cell ◽  
Inhibitory Effects ◽  
Enantiomeric Resolution ◽  
Human Cancer Cell Lines ◽  
Growth Inhibitory
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