Total Synthesis of Nucleoside Antibiotics Amicetin, Plicacetin, and Cytosaminomycin A‐D

2021 ◽  
Author(s):  
Jiqiang Fu ◽  
Peng Xu ◽  
Biao Yu
Keyword(s):  
Total Synthesis ◽  
Nucleoside Antibiotics

Thieme Chemistry Journals Awardees – Where Are They Now? ­Ribosylation of an Acid-Labile Glycosyl Acceptor as a Potential Key Step for the Synthesis of Nucleoside Antibiotics

Synlett ◽  
2017 ◽  
Vol 29 (04) ◽  
pp. 440-446 ◽  
Author(s):  
Christian Ducho ◽  
Daniel Wiegmann ◽  
Anatol Spork ◽  
Giuliana Niro
Keyword(s):  
Total Synthesis ◽  
Antibacterial Agents ◽  
Protecting Group ◽  
Nucleoside Antibiotics ◽  
Naturally Occurring ◽  
Efficient Construction ◽  
Pentenyl Glycosides ◽  
Acid Labile

Naturally occurring nucleoside antibiotics (e.g., muraymycins and caprazamycins) represent attractive lead structures for the development of urgently needed novel antibacterial agents. One major challenge in the total synthesis of muraymycins, caprazamycins, and their analogues is the efficient construction of the densely functionalized aminoribosylated uridine-derived core unit. In order to avoid tedious protecting-group manipulations, we have aimed to conduct the aminoribosylation step with an acid-labile glycosyl acceptor. Therefore, different glycosylation approaches have been studied, with pentenyl glycosides giving the best results.

Total Synthesis of Nucleoside Antibiotics Plicacetin and Streptcytosine A

2018 ◽  
Vol 83 (13) ◽  
pp. 7076-7084 ◽  
Author(s):  
Jiqiang Fu ◽  
Stephane Laval ◽  
Biao Yu
Keyword(s):  
Total Synthesis ◽  
Nucleoside Antibiotics

Total synthesis of Δ9(12)-capnellene-8α,10α-diol

1982 ◽  
Vol 23 (52) ◽  
pp. 5471-5474
Author(s):  
G Pattenden
Keyword(s):  
Total Synthesis

Total synthesis of melleumins A and B and their analogs: Determination of stereochemistry and Wnt signal inhibitory activity

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
M Ishibashi ◽  
S Hanazawa ◽  
Y Uchino ◽  
X Li ◽  
MA Arai
Keyword(s):  
Total Synthesis ◽  
Inhibitory Activity ◽  
Wnt Signal
Sign in / Sign up

Export Citation Format

Share Document