Designing Dual Transglutaminase 2/Histone Deacetylase Inhibitors Effective at Halting Neuronal Death

ChemMedChem ◽

10.1002/cmdc.201700601 ◽

2018 ◽

Vol 13 (3) ◽

pp. 227-230 ◽

Author(s):

Manuela Basso ◽

Huan Huan Chen ◽

Debasmita Tripathy ◽

Mariarosaria Conte ◽

Kim Y. P. Apperley ◽

...

Keyword(s):

Histone Deacetylase ◽

Neuronal Death ◽

Histone Deacetylase Inhibitors ◽

Transglutaminase 2

Download Full-text

Faculty Opinions recommendation of Histone deacetylase inhibitors prevent oxidative neuronal death independent of expanded polyglutamine repeats via an Sp1-dependent pathway.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1012821.187300 ◽

2003 ◽

Author(s):

Albert La Spada

Keyword(s):

Histone Deacetylase ◽

Neuronal Death ◽

Histone Deacetylase Inhibitors ◽

Dependent Pathway

Download Full-text

Histone Deacetylase Inhibitors: A Novel Therapeutic Approach to Huntingtons Disease (Complex Mechanism of Neuronal Death).

Current Alzheimer Research ◽

10.2174/156720506778249407 ◽

2006 ◽

Vol 3 (4) ◽

pp. 403-408 ◽

Author(s):

Ghazaleh Sadri-Vakili ◽

Jang-Ho Cha

Keyword(s):

Histone Deacetylase ◽

Neuronal Death ◽

Therapeutic Approach ◽

Histone Deacetylase Inhibitors ◽

Complex Mechanism ◽

Disease Complex ◽

Novel Therapeutic

Download Full-text

Studies of Benzamide- and Thiol-Based Histone Deacetylase Inhibitors in Models of Oxidative-Stress-Induced Neuronal Death: Identification of Some HDAC3-Selective Inhibitors

ChemMedChem ◽

10.1002/cmdc.200800461 ◽

2009 ◽

Vol 4 (5) ◽

pp. 842-852 ◽

Author(s):

Yufeng Chen ◽

Rong He ◽

Yihua Chen ◽

Melissa A. D'Annibale ◽

Brett Langley ◽

...

Keyword(s):

Oxidative Stress ◽

Histone Deacetylase ◽

Neuronal Death ◽

Histone Deacetylase Inhibitors ◽

Selective Inhibitors

Download Full-text

Histone deacetylase inhibitors prevent oxidative neuronal death independent of expanded polyglutamine repeats via an Sp1-dependent pathway

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.0737363100 ◽

2003 ◽

Vol 100 (7) ◽

pp. 4281-4286 ◽

Author(s):

H. Ryu ◽

J. Lee ◽

B. A. Olofsson ◽

A. Mwidau ◽

A. Deodoglu ◽

...

Keyword(s):

Histone Deacetylase ◽

Neuronal Death ◽

Histone Deacetylase Inhibitors ◽

Dependent Pathway

Download Full-text

271: The Potential Clinical Application of Histone Deacetylase Inhibitors on Androgen Independent Prostate Cancer

The Journal of Urology ◽

10.1016/s0022-5347(18)32538-2 ◽

2006 ◽

Vol 175 (4S) ◽

pp. 90-90

Author(s):

Zhengwang Zhang ◽

Jennifer Stanfield ◽

Jer-Tsong Hsieh

Keyword(s):

Prostate Cancer ◽

Histone Deacetylase ◽

Clinical Application ◽

Histone Deacetylase Inhibitors ◽

Potential Clinical Application ◽

Androgen Independent

Download Full-text

Expression of different histone deacetylases and functional effects of histone deacetylase inhibitors in hepatocellular carcinoma

Zeitschrift für Gastroenterologie ◽

10.1055/s-0037-1612774 ◽

2018 ◽

Vol 56 (01) ◽

pp. E2-E89

Author(s):

P Dietrich ◽

K Freese ◽

W Thasler ◽

C Hellerbrand

Keyword(s):

Hepatocellular Carcinoma ◽

Histone Deacetylase ◽

Histone Deacetylases ◽

Histone Deacetylase Inhibitors

Download Full-text

2074-P: Histone Deacetylase Inhibitors Improve Store-Operated Calcium Entry and Glucose-Stimulated Insulin Secretion in Cytokine-Stressed Pancreatic ß-Cells

Diabetes ◽

10.2337/db20-2074-p ◽

2020 ◽

Vol 69 (Supplement 1) ◽

pp. 2074-P

Author(s):

CHIH-CHUN LEE ◽

TATSUYOSHI KONO ◽

STACI A. WEAVER ◽

PAUL SOHN ◽

CARMELLA EVANS-MOLINA

Keyword(s):

Insulin Secretion ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitors ◽

Calcium Entry ◽

Store Operated Calcium Entry ◽

Glucose Stimulated Insulin Secretion

Download Full-text

Faculty Opinions recommendation of Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1002037.18958 ◽

2001 ◽

Author(s):

Roger Hardie

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitors

Download Full-text

Faculty Opinions recommendation of A functional genetic screen identifies retinoic acid signaling as a target of histone deacetylase inhibitors.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1097071.553043 ◽

2007 ◽

Author(s):

Ted Abel

Keyword(s):

Retinoic Acid ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitors ◽

Genetic Screen ◽

Retinoic Acid Signaling

Download Full-text

Faculty Opinions recommendation of Application of the histone deacetylase inhibitors for the treatment of endometriosis: histone modifications as pathogenesis and novel therapeutic target.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.12224958.13400060 ◽

2011 ◽

Author(s):

Ricardo Buquet ◽

Edgardo Rolla

Keyword(s):

Histone Deacetylase ◽

Histone Modifications ◽

Therapeutic Target ◽

Histone Deacetylase Inhibitors ◽

Novel Therapeutic

Download Full-text