scholarly journals Localization of the M2 muscarinic cholinergic receptor in dendrites, cholinergic terminals, and noncholinergic terminals in the rat basolateral amygdala: An ultrastructural analysis

2016 ◽  
Vol 524 (12) ◽  
pp. 2400-2417 ◽  
Author(s):  
Jay F. Muller ◽  
Franco Mascagni ◽  
Violeta Zaric ◽  
David D. Mott ◽  
Alexander J. McDonald
Keyword(s):  
Basolateral Amygdala ◽  
Cholinergic Receptor ◽  
Ultrastructural Analysis ◽  
Muscarinic Cholinergic Receptor ◽  
Muscarinic Cholinergic ◽  
Cholinergic Terminals

scholarly journals Overnight transdermal scopolamine patch administration has no clear effect on cognition and emotional processing in healthy volunteers

2018 ◽  
Vol 33 (2) ◽  
pp. 255-257 ◽  
Author(s):  
Bernard R Bukala ◽  
Michael Browning ◽  
Philip J Cowen ◽  
Catherine J Harmer ◽  
Susannah E Murphy
Keyword(s):  
Working Memory ◽  
Healthy Volunteers ◽  
Emotional Processing ◽  
Cholinergic Receptor ◽  
Double Blind ◽  
Muscarinic Cholinergic Receptor ◽  
Clear Effect ◽  
Antidepressant Effects ◽  
Muscarinic Cholinergic ◽  
First Time

There has been increasing interest in the antidepressant effects of the muscarinic cholinergic receptor antagonist scopolamine. Here we assess, for the first time, whether a transdermal scopolamine patch is sufficient to induce changes in cognition that are consistent with the reported cognitive and antidepressant effects of scopolamine. A scopolamine or placebo patch was administered to healthy volunteers ( n=33) for 17 h in a double-blind, between-subject procedure. There was no clear effect of scopolamine patch on emotional cognition, verbal or working memory, suggesting that the effective dose of scopolamine available through the patch is too low to represent a viable antidepressant mechanism.

Muscarinic cholinergic receptor subtypes in the hippocampus of aged rats

2002 ◽  
Vol 123 (5) ◽  
pp. 521-528 ◽  
Author(s):  
Seyed Khosrow Tayebati ◽  
Francesco Amenta ◽  
Dahuk El-Assouad ◽  
Damiano Zaccheo
Keyword(s):  
Cholinergic Receptor ◽  
Receptor Subtypes ◽  
Aged Rats ◽  
Muscarinic Cholinergic Receptor ◽  
Muscarinic Cholinergic
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