Morphometric and cytomorphologic characterization of EGFR-mutated cancer cells-comparison between cultured lung cancer cell lines and lung adenocarcinoma clinical samples

2016 ◽  
Vol 44 (9) ◽  
pp. 717-724
Author(s):  
Naoko Nishiyama ◽  
Kenichi Taguchi ◽  
Toshihiro Yokoyama ◽  
Yukito Ichinose ◽  
Masayoshi Kage
Keyword(s):  
Lung Cancer ◽  
Lung Adenocarcinoma ◽  
Cancer Cells ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cancer Cell Lines ◽  
Clinical Samples ◽  
Lung Cancer Cell ◽  
Egfr Mutated

Characterization of the Effects of Cyclooxygenase-2 Inhibition in the Regulation of Apoptosis in Human Small and Non–Small Cell Lung Cancer Cell Lines

2007 ◽  
Vol 14 (9) ◽  
pp. 2678-2684 ◽  
Author(s):  
Mahmood Alam ◽  
Jiang Huai Wang ◽  
John Calvin Coffey ◽  
Syed Suhail Qadri ◽  
Aonghus O’Donnell ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cell Lung Cancer ◽  
Cancer Cell Lines ◽  
Small Cell ◽  
Lung Cancer Cell ◽  
Small Cell Lung

Establishment and characterization of cisplatin-resistant sublines of human lung cancer cell lines

1988 ◽  
Vol 41 (3) ◽  
pp. 462-467 ◽  
Author(s):  
Weon-Seon Hong ◽  
Nagahiro Saijo ◽  
Yasutsuna Sasaki ◽  
Koichi Minato ◽  
Hidehiko Nakano ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Human Lung ◽  
Cancer Cell Lines ◽  
Human Lung Cancer ◽  
Lung Cancer Cell ◽  
Human Lung Cancer Cell

scholarly journals An Extract of Olive Mill Wastewater Downregulates Growth, Adhesion and Invasion Pathways in Lung Cancer Cells: Involvement of CXCR4

Nutrients ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 903 ◽  
Author(s):  
Matteo Gallazzi ◽  
Marco Festa ◽  
Paola Corradino ◽  
Clementina Sansone ◽  
Adriana Albini ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Olive Oil ◽  
Cancer Cells ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cancer Cell Lines ◽  
Olive Mill Wastewater ◽  
Lung Cancer Cells ◽  
Lung Cancer Cell ◽  
Olive Mill

Several diet-derived compounds have been reported to exert antioxidant, anti-proliferative and anti-angiogenic effects in numerous cancers and could be beneficial in cancer prevention. Olive oil production involves the generation of an aqueous phase defined as olive mill wastewater (OMWW), a polluting effluent rich in soluble polyphenols. Here, we assessed the cancer preventive properties exerted by a purified extract of OMWW (A009) for its activity on lung cancer cell lines. Hydroxytyrosol, the most abundant polyphenol present in our A009 extracts, was used as reference molecule in the assays performed. Extracts from OMWW from two different olive oil cultivars were used. We found that the A009 extracts limit lung cancer cell proliferation in a dose and time dependent manner. These effects were associated with the induction of apoptosis. A009 extracts were effective in inhibiting adhesion capabilities on a fibronectin layer accompanied with a reduction in their ability to generate invasive sprouts in a Matrigel layer. The production of chemokine CXCL12 and CXCR4 receptor were reduced by treatment with the extracts. Also, A009 interfered with the production of proangiogenic and pro-inflammatory VEGF, CXCL8, and CCL2 (as detected by FACS analysis) in the lung cell lines. A009 extracts were able to decrease STAT3 phosphorylation in lung cancer cells. Our results show that A009 extracts reduced activities related to tumor cell behavior in lung cancer cell lines, suggesting that they could have a potential cancer preventive role.

scholarly journals Characterization of carfilzomib-resistant non-small cell lung cancer cell lines

2018 ◽  
Vol 144 (7) ◽  
pp. 1317-1327 ◽  
Author(s):  
Neale T. Hanke ◽  
Elliot Imler ◽  
Marilyn T. Marron ◽  
Bruce E. Seligmann ◽  
Linda L. Garland ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cell Lung Cancer ◽  
Cancer Cell Lines ◽  
Small Cell ◽  
Lung Cancer Cell ◽  
Small Cell Lung

Abstract 1707: Establishment and characterization of pemetrexed-resistant lung cancer cell lines

2011 ◽  
Author(s):  
Dan Zhang ◽  
Nobuaki Ochi ◽  
Nagio Takigawa ◽  
Yanyan Chen ◽  
Yasushi Tanimoto ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cancer Cell Lines ◽  
Lung Cancer Cell
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