The impact of repeat fine‐needle aspiration in thyroid nodules categorized as atypia of undetermined significance or follicular lesion of undetermined significance: A single center experience

2020 ◽  
Author(s):  
Fernando Marin ◽  
Raquel Murillo ◽  
Cristina Diego ◽  
Esteban Jodar ◽  
Agustín Acevedo
Keyword(s):  
Fine Needle Aspiration ◽  
Thyroid Nodules ◽  
Needle Aspiration ◽  
Single Center ◽  
Fine Needle ◽  
Single Center Experience ◽  
The Impact ◽  
Undetermined Significance

scholarly journals Punção Aspirativa de Nódulos da Tiroide: Vale a Pena Repetir?

2017 ◽  
Vol 30 (6) ◽  
pp. 472
Author(s):  
Vera Fernandes ◽  
Tânia Pereira ◽  
Catarina Eloy
Keyword(s):  
Fine Needle Aspiration ◽  
Thyroid Nodules ◽  
Significant Proportion ◽  
Cost Effective ◽  
Needle Aspiration ◽  
Fine Needle ◽  
High Concordance ◽  
Benign Nodules ◽  
Cytology Result ◽  
Undetermined Significance

Introduction: The fine-needle aspiration has a significant role in assessing the malignancy risk of thyroid nodules. There is uncertainty regarding the value of repeat fine-needle aspiration in benign nodules. This study aims to evaluate the concordance of results in consecutive fine-needle aspiration and to study the relevance of repetition in benign results.Material and Methods: Retrospective study of the 4800 thyroid nodules fine-needle aspiration held in Instituto de Patologia e Imunologia Molecular da Universidade do Porto between January 1, 2014 and May 2, 2016. Of the initial sample, we selected the repeated fine-needle aspiration on the same nodule.Results: The first fine-needle aspiration result of the 309 nodules underwent revaluation was non-diagnostic in 103 (33.3%), benign in 120 (38.8%) and atypia/follicular lesion of undetermined significance in 86 (27.8%). The agreement between the first and second fine-needle aspiration was significantly higher in cases with an initial benign result (benign: 85.8%, non-diagnostic: 27.2% and atypia/ follicular lesion of undetermined significance: 17.4%, p < 0.005). The fine-needle aspiration repeating motifs in initially benign nodules (n = 78) were repetition suggestion in 58, nodule growth in 17 and suspicious ultrasonographic features in 3.Discussion: The fine-needle aspiration repetition in nodules with initial non-diagnostic and atypia/follicular lesion of undetermined significance result changed the initial diagnosis in a significant proportion of patients, modifying their therapeutic approach. The high concordance of results in initially benign nodules makes fine-needle aspiration repetition not cost-effective in most cases.Conclusion: The fine-needle aspiration should be repeated when the initial cytology result is non-diagnostic or atypia/follicular lesion of undetermined significance.

scholarly journals Surgical Outcome of Thyroid Nodules with Atypia of Undetermined Significance and Follicular Lesion of Undetermined Significance in Fine Needle Aspiration Biopsy

2017 ◽  
Vol 9 (3) ◽  
pp. 100-103
Author(s):  
Saad Alqahtani ◽  
Saif Alsobhi ◽  
Riyadh I Alsalloum ◽  
Saleh N Najjar ◽  
Hindi N Al-Hindi
Keyword(s):  
Fine Needle Aspiration ◽  
Surgical Outcome ◽  
Thyroid Nodules ◽  
Fine Needle Aspiration Biopsy ◽  
Needle Aspiration ◽  
Aspiration Biopsy ◽  
Fine Needle ◽  
Risk Of Malignancy ◽  
Needle Aspiration Biopsy ◽  
Undetermined Significance

ABSTRACT Aim To correlate selected clinical and ultrasonographic (US) characteristics with the final histopathological diagnosis in patients with atypia of undetermined significance (AUS) and follicular lesion of undetermined significance (FLUS), and whether this information can be used in planning the surgical approach. Materials and methods It is a retrospective study including the operated cases of AUS/FLUS from 2011 to 2014 treated at one center. Results This cohort included 87 women and 28 men. To test for independence between categorical variables, the chi-square test was used. There was no significant correlation between age or US variables and final pathological diagnosis. However, final diagnosis of malignancy was higher in men compared with women (64.3 and 41.4% respectively; p = 0.035). Furthermore, a significant association between the diagnosis of repeated fine needle aspiration biopsy (FNAB) and the final pathological diagnosis was noted (benign vs malignant, p = 0.005). Conclusion The FNAB has a significant role in the assessment of thyroid nodules. Our results showed no correlation between age, US variables, and the risk of malignancy. Male gender is associated with higher risk of malignancy. Clinical significance Determining the risk of malignancy and prediction of surgical outcome may help triaging cases for repeat FNA or proceeding to surgery. How to cite this article Alqahtani S, Alsobhi S, Alsalloum RI, Najjar SN, Al-Hindi HN. Surgical Outcome of Thyroid Nodules with Atypia of Undetermined Significance and Follicular Lesion of Undetermined Significance in Fine Needle Aspiration Biopsy. World J Endoc Surg 2017;9(3):100-103.

Performance of the forward-viewing linear echoendoscope for fine-needle aspiration of solid and cystic lesions throughout the gastrointestinal tract: a large single-center experience

2014 ◽  
Vol 28 (6) ◽  
pp. 1801-1807 ◽  
Author(s):  
Alberto Larghi ◽  
Lorenzo Fuccio ◽  
Fabia Attili ◽  
Ester Diana Rossi ◽  
Matteo Napoleone ◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Cystic Lesions ◽  
Single Center ◽  
Fine Needle ◽  
Single Center Experience

Mo1484 The Utility of Endoscopic Ultrasound (EUS)-Fine Needle Aspiration (FNA) for the Diagnosis of Pancreatic Cystic Neuroendocrine Tumors (PCNETs): a Decade of Single Center Experience

2013 ◽  
Vol 77 (5) ◽  
pp. AB399
Author(s):  
Houssam Halawi ◽  
John Dewitt ◽  
Julia K. Leblanc ◽  
Stuart Sherman ◽  
Lee Mchenry ◽  
...  
Keyword(s):  
Neuroendocrine Tumors ◽  
Endoscopic Ultrasound ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Single Center ◽  
Fine Needle ◽  
Single Center Experience

Tu1631 Comparison Between KI-67 Labelling Index on EUS-Guided Fine-Needle Aspiration and Relative Surgical Specimen After Curative Surgery: a Single Center Experience of 49 Consecutive Cases

2015 ◽  
Vol 81 (5) ◽  
pp. AB537
Author(s):  
Filippo Scopelliti ◽  
Sabrina G. Testoni ◽  
Paolo Regi ◽  
Emanuele Dabizzi ◽  
Marco F. Manzoni ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Labelling Index ◽  
Single Center ◽  
Curative Surgery ◽  
Ki 67 ◽  
Surgical Specimen ◽  
Fine Needle ◽  
Single Center Experience

Endoscopic ultrasound-guided fine needle aspiration cytology of solid liver lesions: a large single-center experience

2003 ◽  
Vol 98 (9) ◽  
pp. 1976-1981 ◽  
Author(s):  
John DeWitt ◽  
Julia LeBlanc ◽  
Lee McHenry ◽  
Dan Ciaccia ◽  
Tom Imperiale ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Liver Lesions ◽  
Single Center ◽  
Ultrasound Guided ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Single Center Experience ◽  
Needle Aspiration Cytology

scholarly journals The Impact of Benign Gene Expression Classifier Test Results on the Endocrinologist–Patient Decision to Operate on Patients with Thyroid Nodules with Indeterminate Fine-Needle Aspiration Cytopathology

Thyroid ◽  
2012 ◽  
Vol 22 (10) ◽  
pp. 996-1001 ◽  
Author(s):  
Daniel S. Duick ◽  
Joshua P. Klopper ◽  
James C. Diggans ◽  
Lyssa Friedman ◽  
Giulia C. Kennedy ◽  
...  
Keyword(s):  
Gene Expression ◽  
Fine Needle Aspiration ◽  
Thyroid Nodules ◽  
Needle Aspiration ◽  
Test Results ◽  
Fine Needle ◽  
Patient Decision ◽  
Gene Expression Classifier ◽  
The Impact
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