Pathological changes in the pancreas of fulminant type 1 diabetes and slowly progressive insulin-dependent diabetes mellitus (SPIDDM): innate immunity in fulminant type 1 diabetes and SPIDDM

2011 ◽  
Vol 27 (8) ◽  
pp. 965-970 ◽  
Author(s):  
Tetsuro Kobayashi ◽  
Yoriko Nishida ◽  
Shoichiro Tanaka ◽  
Kaoru Aida
2007 ◽  
pp. 255-266
Author(s):  
D Kantárová ◽  
M Buc

Type 1 diabetes mellitus (DM 1A) is an autoimmune disease belonging to the most frequent chronic diseases of the childhood and young adults. DM 1A results from immune-mediated destruction of the insulin-producing beta cells of the pancreas. It is a genetically determined disease and many genes or genetic regions were found to be associated with its induction. In addition to the insulin-dependent diabetes mellitus 1 (IDDM1) gene, which marks the HLA region, and IDDM2 which marks the insulin gene, significant associations of DM 1A to other IDMM genes or genetic regions we reported. We shortly review recent achievements in the field, and the state of current knowledge.


1994 ◽  
Vol 40 (3) ◽  
pp. 19-22 ◽  
Author(s):  
M. B. Antsiferov ◽  
E. G. Starostina ◽  
G. R. Galstyan ◽  
I. I. Dedov

A prospective follow-up of a random sample of patients with insulin-dependent diabetes mellitus revealed a marked decompensation of carbohydrate metabolism in 98% of the examinees, a high incidence of diabetic ketoacidosis, a long duration of temporary invalidity, and poor adherence of patients to medical recommendations. Assessment of primary health care rendered to patients with type 1 diabetes at district outpatient clinics of Moscow demonstrated its poor efficacy and a necessity to improve the level of specialized diabetologic care.


2008 ◽  
Vol 70 (5) ◽  
pp. 482-486
Author(s):  
Ikko KAJIHARA ◽  
Asako ICHIHARA ◽  
Jyunko HIGO ◽  
Masato KIDOU ◽  
Mikio TODAKA ◽  
...  

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