Respiratory acidosis in adolescents with anorexia nervosa hospitalized for medical stabilization: A retrospective study

2011 ◽  
Vol 45 (1) ◽  
pp. 125-130 ◽  
Author(s):  
Nogah C. Kerem ◽  
Arieh Riskin ◽  
Elvira Averin ◽  
Isaac Srugo ◽  
Amir Kugelman
2007 ◽  
Vol 46 (9) ◽  
pp. 806-811 ◽  
Author(s):  
G. Rossi ◽  
U. Balottin ◽  
M. Rossi ◽  
M. Chiappedi ◽  
E. Fazzi ◽  
...  

2001 ◽  
Vol 34 (3) ◽  
pp. 233-242 ◽  
Author(s):  
Olivier Vanderdonckt ◽  
Michel Lambert ◽  
Maria Cornejo Montero ◽  
Benoît Boland ◽  
Christian Brohet

2020 ◽  
Vol 38 ◽  
Author(s):  
Sofia Alexandra Pereira Pires ◽  
Joana Costa Soares ◽  
Alexandra Maria Branco da Luz ◽  
Pascoal Moleiro

ABSTRACT Objective: To evaluate serum biochemical parameters’ evolution, especially venous blood gas (VBG), in anorexia nervosa (AN), correlating with clinical parameters. Methods: Retrospective study including out-patient AN adolescents, between January 2014 and May 2017. Three evaluations were compared: t1) first consultation; t2) consultation with the lowest body mass index (BMI) z-score and t3) with the highest BMI z-score. Results: A total of 24 adolescents (87.5% females) were included, mean age of presentation of 14.9±1.7 years, onset of symptoms 6.4±3.2 months before the first visit. In t1, BMI z-score of -1.91±1.11 kg/m2 and ideal weight % of 84.3±9.2. Amenorrhea was present in 88%. In t2 the analytical alterations were: altered VBG in 100%, altered ferritin (72% elevated), altered thyroid function (53% with thyroxine decrease), dyslipidemia (31% elevation of high density lipoprotein, 25% hypercholesterolemia), elevation of urea (25%), elevation of alanine aminotransferase (14%), hypoglycemia (14%), anemia (9%). Respiratory acidosis was present in 91% in t1, 100% in t2 and 94% in t3. There was a significant decrease between t2 and t3 in mean pCO2 (57.2 versus 53.6 mmHg; p=0.009) and mean HCO3 (30.0 versus 28.8 mEq/L; p=0.023). Conclusions: Respiratory acidosis and increased ferritin were common in this group. Respiratory acidosis was the most frequent abnormality with significant pCO2 and HCO3 variation in the recovery phase. VBG should be considered in AN evaluation, once it seems to be important in assessing the severity of the disease and its subsequent follow-up.


1974 ◽  
Vol 124 (579) ◽  
pp. 166-172 ◽  
Author(s):  
Sadrudin Bhanji ◽  
James Thompson

Anorexia nervosa is a disorder characterized by loss of appetite, amenorrhoea, and weight loss in the absence of any primary psychiatric or physical illness (Dally and Sargant, 1966). Features which have recently been stated to be of value in distinguishing it from anorexia due to other causes are: denial of illness, bradycardia and lanugo hair (Wright et al., 1969). The weight losses in this condition are usually at least 20 per cent of ideal body weight, depending on the quality and promptness of treatment.


2020 ◽  
Vol 9 (5) ◽  
pp. 1535 ◽  
Author(s):  
Thorsten Koerner ◽  
Verena Haas ◽  
Julia Heese ◽  
Matislava Karacic ◽  
Elmar Ngo ◽  
...  

Background: In mildly to moderately malnourished adolescent patients with anorexia nervosa (AN), accelerated refeeding protocols using higher initial calory supply coupled with phosphate supplements were not associated with a higher incidence of refeeding syndrome (RS). It is unclear whether this is also a feasible approach for extremely malnourished, adult AN patients. Methods: Outcomes of a clinical refeeding protocol involving a targeted initial intake of ≥2000 kcal/day, routine supplementation of phosphate and thiamine as well as close medical monitoring, were evaluated. A retrospective chart review including AN patients with a body mass index (BMI) <13 kg/m² was conducted, to describe changes in weight, BMI, and laboratory parameters (phosphate, creatine kinase, hematocrit, sodium, liver enzymes, and blood count) over four weeks. Results: In 103 female patients (age, mean ± standard deviation (SD) = 23.8 ± 5.3 years), BMI between admission and follow-up increased from 11.5 ± 0.9 to 13.1 ± 1.1 kg/m² and total weight gain within the first four weeks was 4.2 ± 2.0 kg (mean, SD). Laboratory parameter monitoring indicated no case of RS, but continuous normalization of blood parameters. Conclusions: Combined with close medical monitoring and electrolyte supplementation, accelerated refeeding may also be applied to achieve medical stabilization in extremely underweight adults with AN without increasing the risk of RS.


1978 ◽  
Vol 12 (3) ◽  
pp. 145-149 ◽  
Author(s):  
P. J. V. Beumont ◽  
Suzanne F. Abraham ◽  
W. J. Argall ◽  
G. C. W. George ◽  
Daphne E. Glaun

In a retrospective study of case notes a number of experiential and psychological factors were discerned of possible importance to the psychogenesis of anorexia nervosa. These factors included issues of dependence and independence, sexual challenge, concern about obesity, and a variety of other, less specific stresses. Attempts to confirm the findings by means of a prospective study were impeded by difficulties in defining the onset of the illness. While in some patients the occurrence of anorexic type behaviour led immediately to weight loss, in others there was a significant delay between the onset of behavioural change and consequent emaciation.


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