scholarly journals No association between head injury with loss of consciousness and Alzheimer disease pathology—Findings from the University of Manchester Longitudinal Study of Cognition in Normal Healthy Old Age

2019 ◽  
Vol 34 (8) ◽  
pp. 1262-1266
Author(s):  
Andrew C. Robinson ◽  
Yvonne S. Davidson ◽  
Michael A. Horan ◽  
Maggie Cairns ◽  
Neil Pendleton ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Head Injury ◽  
Alzheimer Disease ◽  
Old Age ◽  
Loss Of Consciousness ◽  
The University ◽  
University Of Manchester ◽  
Alzheimer Disease Pathology

The University of Manchester longitudinal study of cognition in normal healthy old age, 1983 through 2003

2019 ◽  
pp. 220-268
Author(s):  
P.M.A. Rabbitt ◽  
L. McInnes ◽  
P. Diggle ◽  
F. Holland ◽  
N. Bent ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Old Age ◽  
The University ◽  
University Of Manchester

scholarly journals Pathological Correlates of Cognitive Impairment in The University of Manchester Longitudinal Study of Cognition in Normal Healthy Old Age

2018 ◽  
Vol 64 (2) ◽  
pp. 483-496 ◽  
Author(s):  
Andrew C. Robinson ◽  
Yvonne S. Davidson ◽  
Michael A. Horan ◽  
Neil Pendleton ◽  
David M.A. Mann
Keyword(s):  
Cognitive Impairment ◽  
Longitudinal Study ◽  
Old Age ◽  
The University ◽  
University Of Manchester

scholarly journals A Comparative Study of Pathological Outcomes in The University of Manchester Longitudinal Study of Cognition in Normal Healthy Old Age and Brains for Dementia Research Cohorts

2020 ◽  
Vol 73 (2) ◽  
pp. 619-632 ◽  
Author(s):  
Andrew C. Robinson ◽  
Stephen Chew-Graham ◽  
Yvonne S. Davidson ◽  
Michael A. Horan ◽  
Federico Roncaroli ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Comparative Study ◽  
Old Age ◽  
Dementia Research ◽  
The University ◽  
University Of Manchester

The University of Manchester Longitudinal Study of Cognition in Normal Healthy Old Age, 1983 through 2003

2004 ◽  
Vol 11 (2-3) ◽  
pp. 245-279 ◽  
Author(s):  
P.M.A. Rabbitt ◽  
L. McInnes ◽  
P. Diggle ◽  
F. Holland ◽  
N. Bent ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Old Age ◽  
The University ◽  
University Of Manchester

scholarly journals Sydney Cross Harland, 19 July 1891 - 8 November 1982

1984 ◽  
Vol 30 ◽  
pp. 297-316
Keyword(s):  
High School ◽  
Old Age ◽  
West Indies ◽  
The West ◽  
King's College ◽  
Village School ◽  
The University ◽  
University Of Manchester ◽  
The Village ◽  
Textile Institute

Sydney Cross Harland was born in Snainton, near Scarborough, Yorkshire, on 19 July 1891. He went to school, first in the village school and then at Scarborough High School. From there he was awarded a scholarship, and went to King’s College, London, and read geology. He graduated with honours in 1912. He grew up a short, stocky man. He was brisk and active in his movements, in spite of a limp which he had through out his life. He went overseas and worked in the West Indies, Brazil and Peru. Here turned to England to become Reader in Genetics and then Professor of Botany in the University of Manchester. In 1919, while working in the West Indies, he was awarded a D.Sc. in botany by King’s College, London. He was elected F. R. S. in 1943 and F.R.S.E. in 1951, and he was made an Honorary Fellow of the Textile Institute for his work on the technological characters of raw cotton. When he retired he lived for some time in Blackheath and then on a property he had acquired in Peru. In old age he returned to a house he had owned since 1932 in Snainton, and there he died on 8 November 1982, at the age of 91.

scholarly journals SOPTI Meeting Abstracts 2021

2021 ◽  
Vol 14 (2) ◽  
pp. 1-3
Author(s):  
Alberto Recchioni
Keyword(s):  
Old Age ◽  
Contact Lenses ◽  
Good Practice ◽  
National Conference ◽  
South Eastern ◽  
The University ◽  
University Of Manchester ◽  
Eastern Norway

After more than a year of blockade due to the Covid-19 pandemic, it was finally possible to return to the events in the presence. The 26th National Conference of the Italian Optometric Association (SOPTI) was held in Bologna on October 10–11, 2021. The theme of the conference was “Good practice in Optometry and Contact Lenses”, with the accent on two topics: the optometric management of the patient in old age and the progression of myopia. Four keynote speakers were invited during the conference: Prof. Rigmor C. Baraas from the University of South-Eastern Norway in Kongsberg, Prof. David B. Elliot from the University of Bradford, Dr. Fabrizio Zeri from the University of Milano Bicocca and the IACLE President, Prof. Phil Morgan, from the University of Manchester. The abstracts from accepted posters and free papers are presented here.

scholarly journals Scores Obtained from a Simple Cognitive Test of Visuospatial Episodic Memory Performed Decades before Death Are Associated with the Ultimate Presence of Alzheimer Disease Pathology

2018 ◽  
Vol 45 (1-2) ◽  
pp. 79-90 ◽  
Author(s):  
Andrew C. Robinson ◽  
Roseanne McNamee ◽  
Yvonne S. Davidson ◽  
Michael A. Horan ◽  
Julie S. Snowden ◽  
...  
Keyword(s):  
Alzheimer Disease ◽  
Test Scores ◽  
Apoe Genotype ◽  
Population Based ◽  
Cognitive Test ◽  
Cognitive State ◽  
Early Interventions ◽  
Braak Stage ◽  
The University ◽  
University Of Manchester

Background: Community- or population-based longitudinal studies of cognitive ability with a brain donation end point offer an opportunity to examine relationships between pathology and cognitive state prior to death. Discriminating the earliest signs of dementing disorders, such as Alzheimer disease (AD), is necessary to undertake early interventions and treatments. Methods: The neuropathological profile of brains donated from The University of Manchester Longitudinal Study of Cognition in Normal Healthy Old Age, including CERAD (Consortium to Establish a Registry for Alzheimer’s Disease) and Braak stage, was assessed by immunohistochemistry. Cognitive test scores collected 20 years prior to death were correlated with the extent of AD pathology present at death. Results: Baseline scores from the Memory Circle test had the ability to distinguish between individuals who developed substantial AD pathology and those with no, or low, AD pathology. Predicted test scores at the age of 65 years also discriminated between these pathology groups. The addition of APOE genotype further improved the discriminatory ability of the model. Conclusions: The results raise the possibility of identifying individuals at future risk of the neuropathological changes associated with AD over 20 years before death using a simple cognitive test. This work may facilitate early interventions, therapeutics and treatments for AD by identifying at-risk and minimally affected (in pathological terms) individuals.

scholarly journals Professor George Archibald Grant Mitchell (1906–1993): his work with penicillin during World War II

2021 ◽  
pp. 096777202110121
Author(s):  
Peter D Mohr ◽  
Stephanie Seville
Keyword(s):  
Nervous System ◽  
World War Ii ◽  
Autonomic Nervous System ◽  
Middle East ◽  
World War ◽  
Army Medical ◽  
Autonomic Nervous ◽  
Penicillin Therapy ◽  
The University ◽  
University Of Manchester

George Archibald Grant Mitchell, OBE, TD, MB, ChB, ChM, MSc, DSc, FRCS (1906–1993) was a professor of anatomy at the University of Manchester from 1946 to 1973. He is mainly remembered for his research in neuroanatomy, especially of the autonomic nervous system. He studied medicine at the Aberdeen University, and after qualifying in 1929 he held posts in surgery and anatomy and worked as a surgeon in the Highlands. In 1939, he joined the Royal Army Medical Corps. He was based in Egypt and the Middle East, where he carried out trials of sulphonamides and penicillin on wounded soldiers; in 1943, he returned to England as Adviser in Penicillin Therapy for 21 Army Group, preparing for the invasion of Europe.

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