Quality of life after free-flap reconstruction in patients with oral and pharyngeal cancer

Head & Neck ◽  
2006 ◽  
Vol 28 (3) ◽  
pp. 210-216 ◽  
Author(s):  
Mari Markkanen-Leppänen ◽  
Antti A. Mäkitie ◽  
Marja-Leena Haapanen ◽  
Erkki Suominen ◽  
Sirpa Asko-Seljavaara
Keyword(s):  
Quality Of Life ◽  
Free Flap ◽  
Flap Reconstruction ◽  
Free Flap Reconstruction ◽  
Pharyngeal Cancer ◽  
Oral And Pharyngeal Cancer

scholarly journals Analysis of speech and swallowing and quality of life in patients undergoing subtotal glossectomy with free flap reconstruction followed by radiotherapy

2021 ◽  
Vol 8 (1) ◽  
pp. 37-41
Author(s):  
Angelos Mantelakis ◽  
Konstantinos Vachtsevanos ◽  
Harry V. M. Spiers ◽  
Christina Gavriilidou ◽  
Stamatis Sapountzis
Keyword(s):  
Quality Of Life ◽  
Free Flap ◽  
Flap Reconstruction ◽  
Free Flap Reconstruction

Quality of life after free-flap tongue reconstruction

2008 ◽  
Vol 123 (5) ◽  
pp. 550-554 ◽  
Author(s):  
D M Hartl ◽  
S Dauchy ◽  
C Escande ◽  
E Bretagne ◽  
F Janot ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Head And Neck ◽  
Free Flap ◽  
Performance Status ◽  
Tongue Base ◽  
Flap Reconstruction ◽  
Free Flap Reconstruction ◽  
European Organization ◽  
Performance Status Scale

AbstractObjective:To analyse correlations between quality of life measures, aspiration and extent of surgical resection in patients who have undergone free-flap tongue reconstruction.Patients and methods:Nine consecutive patients (seven men and two women; average age 51 years) who had been diagnosed with T4a carcinoma of the mobile tongue and/or tongue base and treated by glossectomy, free-flap reconstruction, and either radiation therapy or chemoradiation responded to the European Organization for Research and Treatment of Cancer Head and Neck-35 questionnaire, the performance status scale questionnaire and the hospital anxiety–depression scale questionnaire, an average of 43 months after treatment (range 18–83 months). Aspiration was evaluated by fibre-optic laryngoscopy. Correlations between quality of life domain scores, extent of surgery and the presence of aspiration were evaluated using non-parametric statistical analysis.Results:Scores for the swallowing and aspiration domains of the European Organization for Research and Treatment of Cancer Head and Neck-35 questionnaire were significantly correlated with the extent of tongue base resection (Spearman's correlation, p = 0.037 and 0.042, respectively). Despite a strong correlation between the European Organization for Research and Treatment of Cancer Head and Neck-35 questionnaire results and the performance status scale global scores (correlation coefficient = 0.89, p = 0.048), the performance status scale domain scores were not correlated with the extent of tongue resection. Clinically apparent aspiration was not correlated with the extent of tongue resection, nor were the anxiety or depression scores. However, clinically apparent aspiration was significantly related to the swallowing and aspiration domain scores of the European Organization for Research and Treatment of Cancer Head and Neck-35 questionnaire (p = 0.017 in both cases).Conclusions:Our results imply that the volume of tongue base resection is a major factor in swallowing- and aspiration-related quality of life following tongue resection and free-flap reconstruction. Free-flap reconstruction does not seem to palliate the effect of the loss of functional tongue base volume, as regards swallowing-related quality of life.

scholarly journals Anterior Median Skull Base Reconstruction Using a Vascularized Free Flap: Rationale, Patient Selection and Outcome

2019 ◽  
Vol 81 (01) ◽  
pp. 030-036
Author(s):  
Omer J. Ungar ◽  
Avraham Abergel ◽  
Ahmad Safadi ◽  
Arik Zaretzki ◽  
Ravit Yanko-Arzi ◽  
...  
Keyword(s):  
Quality Of Life ◽  
High Risk ◽  
Skull Base ◽  
Free Flap ◽  
Anterior Skull Base ◽  
Flap Reconstruction ◽  
Free Flap Reconstruction ◽  
Skull Base Reconstruction ◽  
Bony Segment

Objectives To present our method of median anterior skull base (ASB) reconstruction using a subcranial approach with a free flap in cases of naso-fronto-orbital (NFO) bony segment failure and in patients at high risk for future failure of the bony frontal segment. Design This study presents as a retrospective case series. Setting Tertiary university-affiliated medical center. Participants Adult and pediatric patients who underwent median ASB resection via the subcranial approach with a free flap reconstruction were participated in this study. Main Outcome Measures Pathologic outcome and postoperative quality of life (QoL) as assessed by a validated Hebrew version of the “Anterior Skull Base Quality-of-Life Questionnaire.” Results The departmental database yielded 13 suitable patients aged between 15 and 70 years. The main indication (n = 7) for ASB surgery was osteoradionecrosis (ORN) of the NFO bony segment which was first detected at an average of 3.6 years (range: 2–32 years) postradiation therapy. High-risk patients for future ORN of the NFO segment (n = 3) were primarily reconstructed using a vascularized free flap. Nine patients had malignant disease, and four of them were alive without evidence of disease during the follow-up period (average, 48 months). Their QoL was comparable to that of patients who had undergone subcranial ASB resection without free flap reconstruction. Conclusions The ASB median free flap method of reconstruction is a safe and reliable in cases of large complex median ASB defects without orbital resection or maxillectomy. This approach is suitable for patients who had undergone previous surgery, radiotherapy and/or those who present with osteoradionecrosis, as well as for patients with high risk of NFO segment ORN.

Surgical factors associated with patient-reported quality of life outcomes after free flap reconstruction of the oral cavity

Oral Oncology ◽  
2021 ◽  
Vol 123 ◽  
pp. 105574
Author(s):  
Joaquin E. Jimenez ◽  
Marci Lee Nilsen ◽  
William E. Gooding ◽  
Jennifer L. Anderson ◽  
Nayel I. Khan ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Oral Cavity ◽  
Free Flap ◽  
Flap Reconstruction ◽  
Life Outcomes ◽  
Free Flap Reconstruction ◽  
Factors Associated ◽  
Quality Of Life Outcomes ◽  
Patient Reported

Swallowing after free-flap reconstruction in patients with oral and pharyngeal cancer

Oral Oncology ◽  
2006 ◽  
Vol 42 (5) ◽  
pp. 501-509 ◽  
Author(s):  
Mari Markkanen-Leppänen ◽  
Elina Isotalo ◽  
Antti A. Mäkitie ◽  
Eija Rorarius ◽  
Sirpa Asko-Seljavaara ◽  
...  
Keyword(s):  
Free Flap ◽  
Flap Reconstruction ◽  
Free Flap Reconstruction ◽  
Pharyngeal Cancer ◽  
Oral And Pharyngeal Cancer

scholarly journals Olfactory and gustatory functions after free flap reconstruction and radiotherapy for oral and pharyngeal cancer: a prospective follow-up study

2018 ◽  
Vol 275 (4) ◽  
pp. 959-966 ◽  
Author(s):  
Markus Lilja ◽  
Mari Markkanen-Leppänen ◽  
Sanna Viitasalo ◽  
Kauko Saarilahti ◽  
Andrew Lindford ◽  
...  
Keyword(s):  
Free Flap ◽  
Flap Reconstruction ◽  
Free Flap Reconstruction ◽  
Pharyngeal Cancer ◽  
Follow Up Study ◽  
Oral And Pharyngeal Cancer
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