Outcomes of primary radiotherapy with or without chemotherapy for advanced oral cavity squamous cell carcinoma: A systematic review

Head & Neck ◽  
2021 ◽  
Author(s):  
Petra V. Membreno ◽  
Jordan B. Luttrell ◽  
Madhu P. Mamidala ◽  
David L. Schwartz ◽  
D. Neil Hayes ◽  
...  
2009 ◽  
Vol 3 (1) ◽  
pp. 114
Author(s):  
J. Lea ◽  
G. Bachar ◽  
A. Sawka ◽  
D.C. Lakra ◽  
R.W. Gilbert ◽  
...  

2020 ◽  
Vol 140 (10) ◽  
pp. 869-875
Author(s):  
Alexandra Bungum ◽  
Jakob Schmidt Jensen ◽  
Kathrine Kronberg Jakobsen ◽  
Anders Christensen ◽  
Christian Grønhøj ◽  
...  

2017 ◽  
Vol Volume 10 ◽  
pp. 4475-4483 ◽  
Author(s):  
Yurong Kou ◽  
Tengfei Zhao ◽  
Shaohui Huang ◽  
Jie Liu ◽  
Weiyi Duan ◽  
...  

2019 ◽  
Vol 8 (4) ◽  
Author(s):  
Thyago Leite Campos de Campos de Araújo ◽  
Júlio Leite de Araújo Júnior ◽  
Emanuelle de Abreu Moreira Vieira

Introdução: No território brasileiro, a localização anatômica com maior incidência de lesões cancerígenas é em cabeça e pescoço. Sendo caracterizadas como mais agressivas, as lesões localizadas na boca e orofaringe. Afetando, principalmente a capacidade de deglutir e mastigar, no bem estar emocional, na dor e na comunicação. Estes efeitos decorrem da própria doença ou tipo e agressividade do tratamento, gradualmente mais deformantes quando mais tardio o diagnóstico. Objetivo: O presente estudo tem por objetivo relatar um caso de carcinoma in sito em cavidade bucal e orofaringe bem como apresentar uma breve revisão de literatura sobre neoplasias malignas de boca e orofaringe de maior frequência bem como caracterizá-lo clinicamente e alertar sobre os benefícios do diagnóstico precoce. Relato de caso: Paciente, 64 anos, feminina, melanoderma, apresentando lesão eritroplásica em soalho lingual, bordo lateral de língua com extensão para palato mole. Tabagista há 46 anos apresentando ao exame de macroscopia fragmento de tecido mole de formato e superfícies irregulares, consistência elástica, coloração branco acastanhada, medindo em conjunto 1,2 x1,0x 0,5 cm. O exame histopatológico revelou Carcinoma “in situ”. Diante do diagnóstico, a paciente foi encaminhada para o tratamento especializado no hospital de referência na região do Cariri. Conclusão: Conclui-se que o exame clínico minucioso da cavidade oral dos pacientes com fatores de risco 2 e/ou que possuam lesões suspeitas é de fundamental importância para profissionais como o Cirurgião-Dentista e Médico.Descritores: Câncer; Boca; Orofaringe; Odontologia.ReferênciasGupta B, Bhattacharyya A, Singh A, Sah K, Gupta V. Basaloid squamous cell carcinoma - A rare and aggressive variant of squamous cell carcinoma: A case report and review of literature. Natl J Maxillofac Surg. 2018;9(1):64-8.Heera R, Ayswarya T, Padmakumar SK, Ismayil P. Basaloid squamous cell carcinoma of oral cavity: Report of two cases. J Oral Maxillofac Pathol. 2016;20(3):545Tomblinson CM, Nagel TH, Hu LS, Zarka MA, Hoxworth JM. Median lingual lymph nodes: prevalence on imaging and potential implications for oral cavity cancer staging. J Comput Assist Tomogr. 2017;41(4):528-34.Varela-Centelles P, López-Cedrun JL, Fernández-Sanromán J, Seone-Romero JM, Santos de Melo N, Álvarez-Nóvoa P  et al. Key points and time intervals for early diagnosis in symptomatic oral cancer: A systematic review. Int J Oral Maxillofac Surg. 2017;46(1):1-10.Jia J, Jia MQ, Zou HX. Lingual lymph nodes in patients with squamous cell carcinoma of the tongue and the floor of the mouth. Head Neck. 2018;40(11):2383-88.Swiecicki PL, Malloy KM, Worden FP. Advanced oropharyngeal squamous cell carcinoma: Pathogenesis, treatment, and novel therapeutic approaches. World J Clin Oncol. 2016;7(1):15-26.Balica NC, Poenaru M, Doroş CI, Baderca F, Preda MA, Iovan VC et al.The management of the oropharyngeal anterior wall cancer. Rom J Morphol Embryol. 2018;59(1):113-19.Dahlstrom KR, Bell D, Hanby D, Li G, Wang LE, Wei Q et al. Socioeconomic characteristics of patients with oropharyngeal carcinoma according to tumor HPV status, patient smoking status, and sexual behavior. Oral Oncol. 2015;51(9):832-38.Bonomo P, Merlotti A, Olmetto E, Bianchi A, Desideri I, Bacigalupo A et al. What is the prognostic impact of FDG PET in locally advanced head and neck squamous cellcarcinoma treated with concomitant chemo-radiotherapy? A systematic review and meta-analysis. Eur J Nucl Med Mol Imaging. 2018;45(12):2122-38.Picard A, Arowas L, Piroth L, Heard I, Ferry T, ORL-HIV-HPV studt group. Head and neck squamous cell carcinoma in people living with HIV in France. Med Mal Infect. 2018;48(8):503-8.


2021 ◽  
Vol 6 (1) ◽  
pp. 54
Author(s):  
Nelly Nainggolan ◽  
Wahyu Hidayat

ABSTRACTIntroduction: As many as 90%-95% cases of oral cancer are oral squamous cell carcinoma. In South and Southeast Asia, the prevalence of oral cancer is high. Oral cancer is ranked sixth for the most frequent malignancies in Asia with nearly 274,300 new cases occurring every year. Head and Neck Squamous Cell Carcinoma is one of the main public health concerns with 1-2% incident of all cancers worldwide and is also the sixth most common malignant tumor. Human Papillomavirus (HPV) is a DNA virus which is also known as the cause of head and neck cancer. Among all malignancies, oral cancer is one of the conditions where salivary examination can be used to detect oral cancer because it contacts directly with the lesions. The relationship between human papilloma virus (HPV) and oral squamous cell carcinoma has been extensively studied and shows that HPV-16 & 18 can be detected in saliva, serum or plasma samples and patient biopsies. Purpose: This systematic review aims to reveal the presence of human papilloma virus in cancerous and pre-cancerous lesions of the oral cavity by examining saliva, serum or plasma. Methods: Systematic Review was carried out using the PRISMA method. Articles with clinical trial types sourced from electronic searches were obtained through the PubMed, Research Gate and Google Scholar portals using keywords: Human Papilloma Virus, Oral Cancer, and Saliva. Conclusion: Based on the results, it is concluded that HPV is detected in oral cavity cancers, oropharyngeal, oral squamous cell carcinoma and Oral Potentially Malignant Disorders.Keywords : Human Papilloma Virus, Oral cancer, Saliva


Oral Oncology ◽  
2021 ◽  
Vol 122 ◽  
pp. 105540
Author(s):  
Fabio Ferreli ◽  
Bianca Maria Festa ◽  
Andrea Costantino ◽  
Luca Malvezzi ◽  
Giovanni Colombo ◽  
...  

Head & Neck ◽  
2009 ◽  
pp. NA-NA ◽  
Author(s):  
Jane Lea ◽  
Gideon Bachar ◽  
Anna M. Sawka ◽  
Deepak C. Lakra ◽  
Ralph W. Gilbert ◽  
...  

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