Prevalence of occult level 2b nodal metastases in cN0 squamous cell carcinoma of the oral cavity: A systematic review and meta-analysis

Oral Oncology ◽  
2021 ◽  
Vol 122 ◽  
pp. 105540
Author(s):  
Fabio Ferreli ◽  
Bianca Maria Festa ◽  
Andrea Costantino ◽  
Luca Malvezzi ◽  
Giovanni Colombo ◽  
...  
Keyword(s):  
Systematic Review ◽  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Meta Analysis ◽  
Nodal Metastases

O175. Metastases to level IIb in squamous cell carcinoma of the oral cavity: A systematic review and meta-analysis

2009 ◽  
Vol 3 (1) ◽  
pp. 114
Author(s):  
J. Lea ◽  
G. Bachar ◽  
A. Sawka ◽  
D.C. Lakra ◽  
R.W. Gilbert ◽  
...  
Keyword(s):  
Systematic Review ◽  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Meta Analysis

scholarly journals Cervical level IIb metastases in squamous cell carcinoma of the oral cavity: a systematic review and meta-analysis

2017 ◽  
Vol Volume 10 ◽  
pp. 4475-4483 ◽  
Author(s):  
Yurong Kou ◽  
Tengfei Zhao ◽  
Shaohui Huang ◽  
Jie Liu ◽  
Weiyi Duan ◽  
...  
Keyword(s):  
Systematic Review ◽  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Meta Analysis ◽  
Cervical Level

Metastases to level IIb in squamous cell carcinoma of the oral cavity: A systematic review and meta-analysis

Head & Neck ◽  
2009 ◽  
pp. NA-NA ◽  
Author(s):  
Jane Lea ◽  
Gideon Bachar ◽  
Anna M. Sawka ◽  
Deepak C. Lakra ◽  
Ralph W. Gilbert ◽  
...  
Keyword(s):  
Systematic Review ◽  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Meta Analysis

Outcomes of primary radiotherapy with or without chemotherapy for advanced oral cavity squamous cell carcinoma: A systematic review

Head & Neck ◽  
2021 ◽  
Author(s):  
Petra V. Membreno ◽  
Jordan B. Luttrell ◽  
Madhu P. Mamidala ◽  
David L. Schwartz ◽  
D. Neil Hayes ◽  
...  
Keyword(s):  
Systematic Review ◽  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Primary Radiotherapy

scholarly journals Tumor-Infiltrating Lymphocytes in the Tumor Microenvironment of Laryngeal Squamous Cell Carcinoma: Systematic Review and Meta-Analysis

Biomedicines ◽  
2021 ◽  
Vol 9 (5) ◽  
pp. 486
Author(s):  
Juan P. Rodrigo ◽  
Mario Sánchez-Canteli ◽  
Fernando López ◽  
Gregory T. Wolf ◽  
Juan C. Hernández-Prera ◽  
...  
Keyword(s):  
Systematic Review ◽  
Squamous Cell Carcinoma ◽  
Tumor Microenvironment ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Prognostic Value ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Meta Analysis ◽  
Tumor Infiltrating Lymphocytes ◽  
Infiltrating Lymphocytes

The presence of tumor-infiltrating lymphocytes (TIL) in the tumor microenvironment has been demonstrated to be of prognostic value in various cancers. In this systematic review and meta-analysis, we investigated the prognostic value of TIL in laryngeal squamous cell carcinoma (LSCC). We performed a systematic search in PubMed for publications that investigated the prognostic value of TIL in LSCC. A meta-analysis was performed including all studies assessing the association between TIL counts in hematoxylin-eosin (HE)-stained sections, for CD8+ and/or CD3+/CD4+ TIL and overall survival (OS) or disease-free survival (DFS). The pooled meta-analysis showed a favorable prognostic role for stromal TIL in HE sections for OS (HR 0.57, 95% CI 0.36–0.91, p = 0.02), and for DFS (HR 0.56, 95% CI 0.34–0.94, p = 0.03). High CD8+ TIL were associated with a prolonged OS (HR 0.62, 95% CI 0.4–0.97, p = 0.04) and DFS (HR 0.73, 95% CI 0.34–0.94, p = 0.002). High CD3+/CD4+ TIL demonstrated improved OS (HR 0.32, 95% CI 0.16–0.9, p = 0.03) and DFS (HR 0.23, 95% CI 0.10–0.53, p = 0.0005). This meta-analysis confirmed the favorable prognostic significance of TIL in LSCC. High stromal TIL evaluated in HE sections and intra-tumoral and stromal CD3+, CD4+ and/or CD8+ TIL might predict a better clinical outcome.

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