Acute Fatty Liver of Pregnancy From 18 Weeks’ Gestation

Hepatology ◽  
2020 ◽  
Vol 71 (6) ◽  
pp. 2167-2169 ◽  
Author(s):  
Mimi Wong ◽  
Frances Hills ◽  
Katrina Vogler ◽  
Ibrahim Zardawi ◽  
Nirjhar Nandi
Keyword(s):  
Fatty Liver ◽  
Acute Fatty Liver

scholarly journals Diabetes Insipidus Accompanied with Acute Kidney Injury, which was Revealed by Acute Fatty Liver of Pregnancy.

2011 ◽  
Vol 100 (10) ◽  
pp. 3044-3047
Author(s):  
Hiroki Takimoto ◽  
Katsuyuki Nagatoya ◽  
Yoko Yamauchi ◽  
Hirohisa Matsuda ◽  
Tatsuhiko Mori ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Fatty Liver ◽  
Diabetes Insipidus ◽  
Kidney Injury ◽  
Acute Fatty Liver

Acute Fatty Liver

2018 ◽  
pp. 13-15
Author(s):  
Aiyuan Li ◽  
Weike Tao
Keyword(s):  
Fatty Liver ◽  
Acute Fatty Liver

Readiness, Recognition, Response, and Reporting in a Case of Acute Fatty Liver of Pregnancy

2018 ◽  
Vol 22 (6) ◽  
pp. 481-488
Author(s):  
Jane Ciaramella
Keyword(s):  
Fatty Liver ◽  
Recognition Response ◽  
Acute Fatty Liver

scholarly journals ACUTE FATTY LIVER OF PREGNANCY MASQUERADING AS HELLP SYNDROME

2018 ◽  
Vol 5 (20) ◽  
pp. 1592-1595
Author(s):  
Santhosh Narayanan ◽  
Divya Prakash ◽  
Gomathy Subramaniam ◽  
Lakshminarayanan Lakshminarayanan
Keyword(s):  
Fatty Liver ◽  
Hellp Syndrome ◽  
Acute Fatty Liver

scholarly journals Comparison of Maternal and Neonatal Outcomes between Acute Fatty Liver of Pregnancy and Hemolysis, Elevated Liver Enzymes and Low Platelets Syndrome: A Retrospective Cohort Study

2020 ◽  
Author(s):  
Sau Xiong Ang ◽  
Chie-Pein Chen ◽  
Fang-Ju Sun ◽  
Chen-Yu Chen
Keyword(s):  
Cohort Study ◽  
Fatty Liver ◽  
Retrospective Cohort Study ◽  
Hellp Syndrome ◽  
Retrospective Cohort ◽  
Liver Enzymes ◽  
Neonatal Outcomes ◽  
Elevated Liver Enzymes ◽  
Acute Fatty Liver ◽  
Maternal And Neonatal Outcomes

Abstract Background: Acute fatty liver of pregnancy (AFLP) and hemolysis, elevated liver enzymes and low platelets (HELLP) syndrome are two uncommon disorders that mimic each other clinically, but are distinct pathophysiologically. This study aimed to compare maternal and neonatal outcomes between AFLP and HELLP syndrome.Methods: This retrospective cohort study was performed at a tertiary referral center in Taiwan between June 2004 and April 2020. We used the Swansea Criteria to diagnose AFLP, and the Tennessee Classification System to diagnose HELLP syndrome. Maternal characteristics, laboratory data, complications, and neonatal outcomes were analyzed.Results: During the study period, 21 women had AFLP and 80 women had HELLP syndrome. There was a higher rate of preeclampsia (95.0% versus 23.8%) in the HELLP syndrome group compared to the AFLP group. However, the AFLP group had more other maternal complications including jaundice (85.7% versus 13.8%), acute kidney injury (61.9% versus 15.0%), disseminated intravascular coagulopathy (66.7% versus 8.8%), and sepsis (47.6% versus 10.0%) compared to the HELLP syndrome group. Nevertheless, higher rates of small for gestational age neonates (57.1% versus 33.3%), neonatal respiratory distress syndrome (39.2% versus 8.3%) and neonatal sepsis (34.2% versus 12.5%) were noted in the HELLP syndrome group.Conclusions: AFLP is associated with a higher rate of multiple organ dysfunction in mothers, whereas HELLP syndrome is associated with a higher rate of neonatal morbidity.

scholarly journals Sickle cell anaemia in vaso-occlusive crisis and acute fatty liver of pregnancy: a case report

2020 ◽  
Vol 54 (3) ◽  
pp. 201-203
Author(s):  
Michael Ezeanochie ◽  
Oghenefegor Olokor ◽  
Ofure Yamah
Keyword(s):  
Case Report ◽  
Fatty Liver ◽  
Sickle Cell ◽  
Sickle Cell Anaemia ◽  
Elevated Serum ◽  
Simultaneous Occurrence ◽  
Published Data ◽  
Care Providers ◽  
Delay In Diagnosis ◽  
Acute Fatty Liver

Acute fatty liver of pregnancy (AFLP) is an uncommon condition that manifests in the third trimester of pregnancy.Its association with vaso-occlusive crisis from Sickle Cell Anaemia is not common. Published data on the simultaneous occurrence of these two conditions is rare, hence this case report. A 32-year-old gravida 3 para 1+1 lady, with Sickle Cell Anaemia, had a vaso-occlusive crisis in association with AFLP at 32 weeks’ gestation, and the outcome of her management was successful. AFLP is a rare late-gestational event affecting about 1 in 10,000 to 15,000 pregnancies. The exact aetiology is not known. Profound hypoglycaemia and jaundice with elevated serum transaminases are recognized features of AFLP.These features may also be seen in haemoglobinopathies. The simultaneous occurrence of AFLP and Sickle Cell Anaemia may result in overlap of symptoms and delay in diagnosis and treatment. Therefore, maintaining a high index of suspicion is key. The cornerstone for treatment remains prompt delivery and supportive care. AFLP can coexist with Sickle cell crises. It is important that care providers, especially in populations with high burden of Sickle Cell Anaemia, consider this as a differential diagnosis, especially when the jaundice is associated with profound or recurring episodes of hypoglycaemia. Prompt diagnosis and delivery in a multidisciplinary approach is important to avoid adverse maternal and foetal outcomes.Keywords: Vaso-occlusive crises, acute fatty liver of pregnancy, hypoglycaemia, Sickle-cell anaemiaFunding: No funding sources

Prenatal predictors in postpartum recovery for acute fatty liver of pregnancy: experiences at a tertiary referral center

2015 ◽  
Vol 293 (6) ◽  
pp. 1185-1191 ◽  
Author(s):  
Jinlai Meng ◽  
Shan Wang ◽  
Yongzhong Gu ◽  
Hong Lv ◽  
Jinjiao Jiang ◽  
...  
Keyword(s):  
Fatty Liver ◽  
Tertiary Referral ◽  
Tertiary Referral Center ◽  
Referral Center ◽  
Acute Fatty Liver ◽  
Postpartum Recovery

scholarly journals Mild Clinical Presentation of Acute Fatty Liver in the Second Trimester of Pregnancy

2011 ◽  
Vol 2011 ◽  
pp. 1-3 ◽  
Author(s):  
Alaeddine Yassin ◽  
Walid Denguezli ◽  
Anissa Fessi ◽  
Leila Njim ◽  
Raja Falah ◽  
...  
Keyword(s):  
Fatty Liver ◽  
Clinical Presentation ◽  
Second Trimester ◽  
Acute Fatty Liver ◽  
Mild Clinical Presentation

We report a case of 29 years old woman who was diagnosed with acute fatty liver of pregnancy at 23 weeks of gestation with unusual evolution (pregnancy prolonged until 36 weeks of gestation) to draw attention on the possibility of occurrence of this pathology in the second trimester of pregnancy even with a milder clinical presentation and course.

Markedly higher sFlt-1/PlGF ratio in a woman with acute fatty liver of pregnancy compared with HELLP syndrome

2018 ◽  
Vol 45 (1) ◽  
pp. 96-103 ◽  
Author(s):  
Hirotada Suzuki ◽  
Shiho Nagayama ◽  
Chikako Hirashima ◽  
Kayo Takahashi ◽  
Hironori Takahashi ◽  
...  
Keyword(s):  
Fatty Liver ◽  
Hellp Syndrome ◽  
Acute Fatty Liver ◽  
Plgf Ratio

The Hibernating Bear—A Good Analogy to Explain Why Acute Fatty Liver of Pregnancy Manifests in Late Pregnancy

2018 ◽  
Vol 113 (2) ◽  
pp. 307-308 ◽  
Author(s):  
Uday Zachariah ◽  
Ashish Goel ◽  
K A Balasubramanian ◽  
C E Eapen
Keyword(s):  
Fatty Liver ◽  
Late Pregnancy ◽  
Acute Fatty Liver ◽  
Good Analogy
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