In vivo localization of a bispecific antibody which targets human t lymphocytes to lyse human colon cancer cells

1989 ◽  
Vol 43 (3) ◽  
pp. 501-507 ◽  
Author(s):  
Ian G. Barr ◽  
Sylvia Miescher ◽  
Vladimir Von Fliedner ◽  
Franz Buchegger ◽  
Catherine Barras ◽  
...  
2019 ◽  
Vol 8 (12) ◽  
pp. 5662-5672 ◽  
Author(s):  
Sonoko Chikamatsu ◽  
Ken Saijo ◽  
Hiroo Imai ◽  
Koichi Narita ◽  
Yoshifumi Kawamura ◽  
...  

1994 ◽  
Vol 14 (1) ◽  
pp. 207-213 ◽  
Author(s):  
E Chu ◽  
D M Voeller ◽  
K L Jones ◽  
T Takechi ◽  
G F Maley ◽  
...  

Translation of thymidylate synthase (TS) mRNA is controlled by its own protein product, TS, in an autoregulatory manner. Direct binding of TS protein to two different cis-acting elements on the TS mRNA is associated with this translational regulation. In this study, an immunoprecipitation-reverse transcription-PCR technique was used to identify a TS ribonucleoprotein (RNP) complex in cultured human colon cancer cells. Using antibodies specific for TS protein, we show that TS is complexed in vivo with its own TS RNA. Furthermore, evidence demonstrating a direct interaction between the mRNA of the nuclear oncogene c-myc and TS protein is presented.


2013 ◽  
Vol 11 (9) ◽  
pp. 973-985 ◽  
Author(s):  
Yan Bao ◽  
Kuniaki Mukai ◽  
Takako Hishiki ◽  
Akiko Kubo ◽  
Mitsuyo Ohmura ◽  
...  

2010 ◽  
Vol 58 (24) ◽  
pp. 12999-13005 ◽  
Author(s):  
Hsu-Feng Lu ◽  
Yuan-Liang Chen ◽  
Jai-Sing Yang ◽  
Yi-Yuan Yang ◽  
Jia-You Liu ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document