The secotioid form of Lentinus tigrinus : genetics and development of a fungal morphological innovation

1994 ◽  
Vol 81 (4) ◽  
pp. 466-478 ◽  
Author(s):  
David S. Hibbett ◽  
Akihiko Tsuneda ◽  
Shigeyuki Murakami
2020 ◽  
Vol 22 (11) ◽  
pp. 1079-1088
Author(s):  
Hamid R. Pourianfar ◽  
Safoora Mohammadnejad ◽  
Shadi Shahtahmasebi ◽  
Alireza Madjid Ansari ◽  
Saaid Zibaei ◽  
...  

Evolution ◽  
2020 ◽  
Vol 74 (7) ◽  
pp. 1514-1524
Author(s):  
Chad M. Eliason ◽  
Lorian Straker ◽  
Sunghwan Jung ◽  
Shannon J. Hackett

2019 ◽  
Vol 2019 ◽  
pp. 1-15 ◽  
Author(s):  
Yingnyu Gao ◽  
Ying Wáng ◽  
Ying Wāng ◽  
Yingying Wu ◽  
Hongyu Chen ◽  
...  

Fungal immunomodulatory proteins (FIPs) are a class of small proteins that have been extensively studied for their immunomodulatory activities. In this study, two novel FIPs from Lentinus tigrinus were identified and named Fip-lti1 and Fip-lti2. The bioactive characteristics of Fip-lti1 and Fip-lti2 were compared to a well-known FIP (LZ-8 from Ganoderma lucidum) to investigate the effect of Fip-lti1 and Fip-lti2 expression on concanavalin A- (Con A-) induced liver oxidative injury. Both Fip-lti1 and Fip-lti2 protected the livers from Con A-induced necrosis, as evidenced by decreased serum aminotransferase levels (AST, ALT) and relieved liver histology. Levels of proinflammatory cytokines (TNF-α, IL-1β, and IL-6) and oxidative stress (SOD, MDA) were shown to be reduced by expressing Fip-lti1 and Fip-lti2. In addition, the hepatoprotective effect of Fip-lti1, Fip-lti2, and LZ-8 correlated with ameliorating the imbalance of Th1/Th2 (IFN-γ/IL-4). The observed liver protection of Fip-lti1 and Fip-lti2 was mechanistically explored. Treatments with Fip-lti1 and Fip-lti2 regulated GATA3/T-bet expression, activated the decreased Nrf-2/HO-1 pathway, and countered the upregulated NLRP3/ASC/NF-κBp65 signaling in Con A-stimulated liver injury. Nrf2 activation was shown to be involved in the mechanisms underlying the protection of Fip-lti by RNA interference. In conclusion, we identified two new fungal proteins (Fip-lti1 and Fip-lti2) that can protect the liver from Con A-induced liver oxidative injury through the Nrf2/NF-κB/NLRP3/IL-1β pathway.


2019 ◽  
Vol 6 (5) ◽  
pp. 182087 ◽  
Author(s):  
Jennifer A. Clack ◽  
Marcello Ruta ◽  
Andrew R. Milner ◽  
John E. A. Marshall ◽  
Timothy R. Smithson ◽  
...  

The enigmatic tetrapod Acherontiscus caledoniae from the Pendleian stage of the Early Carboniferous shows heterodontous and durophagous teeth, representing the earliest known examples of significant adaptations in tetrapod dental morphology. Tetrapods of the Late Devonian and Early Carboniferous (Mississippian), now known in some depth, are generally conservative in their dentition and body morphologies. Their teeth are simple and uniform, being cone-like and sometimes recurved at the tip. Modifications such as keels occur for the first time in Early Carboniferous Tournaisian tetrapods. Acherontiscus , dated as from the Pendleian stage, is notable for being very small with a skull length of about 15 mm, having an elongate vertebral column and being limbless. Cladistic analysis places it close to the Early Carboniferous adelospondyls, aïstopods and colosteids and supports the hypothesis of ‘lepospondyl’ polyphyly. Heterodonty is associated with a varied diet in tetrapods, while durophagy suggests a diet that includes hard tissue such as chitin or shells. The mid-Carboniferous saw a significant increase in morphological innovation among tetrapods, with an expanded diversity of body forms, skull shapes and dentitions appearing for the first time.


2020 ◽  
Vol 30 (13) ◽  
pp. 2645-2648
Author(s):  
Chris D. Whitewoods ◽  
Joseph Cammarata ◽  
Zoe Nemec Venza ◽  
Stephanie Sang ◽  
Ashley D. Crook ◽  
...  

1965 ◽  
Vol 52 (6Part1) ◽  
pp. 599-605 ◽  
Author(s):  
L. J. Littlefield ◽  
R. D. Wilcoxson ◽  
T. W. Sudia
Keyword(s):  

2007 ◽  
Vol 7 (1) ◽  
pp. 60 ◽  
Author(s):  
Marta Ferraroni ◽  
Nina M Myasoedova ◽  
Vadim Schmatchenko ◽  
Alexey A Leontievsky ◽  
Ludmila A Golovleva ◽  
...  

1987 ◽  
Vol 65 (5) ◽  
pp. 1053-1060 ◽  
Author(s):  
Philip D. Gingerich

Mammals have an unusually good Cenozoic fossil record providing evidence of their evolutionary diversification. We view this record in hindsight, which biases our perception in many ways. Overall worldwide diversity appears to increase exponentially through time, while intensive sampling in local areas indicates that modern levels of diversity were achieved early in the Cenozoic. The evident significance of Pleistocene extinctions depends critically on how extinction rates are quantified. Our taxonomic hierarchy probably reflects the number of major faunal turnovers a group has survived rather than declining intensity of successive turnovers. Morphological innovation and taxonomic diversification appear following intervals of climatic cooling, suggesting that major features of evolution are extrinsically controlled. Favorable stratigraphic settings yield detailed records of gradual anagenesis and cladogenesis in mammals, with intermediates present as evidence of transition. The apparent dichotomy between high evolutionary rates measured by neontologists over short intervals of time and low evolutionary rates measured by paleontologists over long intervals of time disappears when rates are measured on intermediate scales of time. Microevolution and macroevolution are manifestations of common underlying processes expressed on different time scales.


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