scholarly journals Ketamine attenuates cytochrome p450 aromatase gene expression and estradiol-17β levels in zebrafish early life stages

2013 ◽  
Vol 34 (5) ◽  
pp. 480-488 ◽  
Author(s):  
William J. Trickler ◽  
Xiaoqing Guo ◽  
Elvis Cuevas ◽  
Syed F. Ali ◽  
Merle G. Paule ◽  
...  
2015 ◽  
Vol 22 (21) ◽  
pp. 16319-16328 ◽  
Author(s):  
Jennifer Bräunig ◽  
Sabrina Schiwy ◽  
Oliver Broedel ◽  
Yvonne Müller ◽  
Marcus Frohme ◽  
...  

2014 ◽  
Vol 117 (1) ◽  
pp. 66-72 ◽  
Author(s):  
B.N.V. Lakshminarayana ◽  
V. Praveen Chakravarthi ◽  
K.V. Brahmaiah ◽  
V.H. Rao

2021 ◽  
Vol 38 (2) ◽  
pp. 247-252
Author(s):  
Guler Unal ◽  
Emily Marquez ◽  
Mara H. O'brien ◽  
Pericles Stavropoulos ◽  
Ian P. Callard

In this study, we aimed to clone brain-derived Cyp19b and ovary-derived Cyp19a the P450 aromatase gene isoforms and to indicate the expression levels of these genes in the hypothalamus and ovary tissues from reproductively arrested ovarian development (RA) and non-arrested ovarian development (RN) Alburnus tarichi from Lake Van, Turkey. The expression levels of Cyp19b and Cyp19a genes were predominant in the hypothalamus and ovary, respectively. The level of Cyp19b mRNA was significantly lower in the hypothalamus and ovary from RA fish than in the hypothalamus and ovary from RN fish (P<0.05). The expression level of Cyp19a was significantly lower in the ovary of RA fish (P<0.05) than RN fish while no difference was found in the hypothalamus of both RA and RN fish (P<0.05). According to these findings, we suggest that the RA fish represent a segment of the population and these fish may be more sensitive to endocrine disruption compound/s than others.


2011 ◽  
Vol 26 (2) ◽  
pp. 195-206 ◽  
Author(s):  
Sonia M. Johns ◽  
Nancy D. Denslow ◽  
Michael D. Kane ◽  
Karen H. Watanabe ◽  
Edward F. Orlando ◽  
...  

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