Sericin-carboxymethyl cellulose porous matrices as cellular wound dressing material

2013 ◽  
Vol 102 (6) ◽  
pp. 1928-1940 ◽  
Author(s):  
Sunita Nayak ◽  
S. C. Kundu

2014 ◽  
Vol 66 ◽  
pp. 245-253 ◽  
Author(s):  
Lihong Fan ◽  
Xiaoyu Zhou ◽  
Penghui Wu ◽  
Weiguo Xie ◽  
Hua Zheng ◽  
...  


2020 ◽  
Vol 147 ◽  
pp. 1239-1247 ◽  
Author(s):  
Soodeh Sadeghi ◽  
Jhamak Nourmohammadi ◽  
Azadeh Ghaee ◽  
Neda Soleimani


2018 ◽  
Vol 106 ◽  
pp. 1218-1234 ◽  
Author(s):  
Nádia S.V. Capanema ◽  
Alexandra A.P. Mansur ◽  
Anderson C. de Jesus ◽  
Sandhra M. Carvalho ◽  
Luiz C. de Oliveira ◽  
...  


RSC Advances ◽  
2015 ◽  
Vol 5 (125) ◽  
pp. 103036-103046 ◽  
Author(s):  
Ali Hebeish ◽  
S. Sharaf

Graft copolymerization of DADMAC with a MBA crosslinking agent was achieved on water soluble carboxymethyl cellulose with an APS initiator. A CuO nanocomposite hydrogel was formed in situ on cotton. The synthesis of Ag/CMC-DADMAC hydrogel nanocomposites was also studied.



2019 ◽  
Vol 28 (Sup10) ◽  
pp. S4-S9 ◽  
Author(s):  
Reiva Farah Dwiyana ◽  
Yuri Yogya ◽  
Srie Prihianti Gondokaryono ◽  
Inne Arline Diana ◽  
Oki Suwarsa ◽  
...  

Objective: To evaluate the efficacy of a biocellulose, a carboxymethyl cellulose and a normal saline wound dressing in the wound care management of epidermolysis bullosa (EB) skin wounds. Methods: This was a single-blind, randomised controlled trial involving wounds from patients with EB. Wounds were divided into three groups: group I with biocellulose wound dressing, group II with carboxymethyl cellulose wound dressing and group III with normal saline wound dressing as a control. All dressing changes and wound parameters were recorded. Observations were conducted every three days until complete wound closure or up to one month. Results: The outcomes of treatment of 36 wounds from four patients were evaluated in this study. Mean healing time in group I was seven days, eight days in group II and 14 days in group III. There were significant differences in healing times between group I and group III (p=0.0001) and between group II and III (p=0.001). The results showed a significant reduction in the percentage of wounds area on day three for each group: 51.7% in group I, 51.9% in group II, and 26% for group III. All wounds in groups I and II had healed at day 12 (100%) and at day 24 (100%) in group III. There were significant differences in the reduction of percentage wound area between group I and group III at day three (p=0.044) and day six (p=0.000), and between group II and III at day six (p=0.003). Conclusion: The study demonstrates that both the biocellulose and the carboxymethyl cellulose wound dressings significantly reduced percentage wound areas and complete healing times compared with the normal saline wound dressing in EB skin wounds, demonstrating they are both equally good for wound care management in EB patients.



2019 ◽  
Vol 20 (10) ◽  
pp. 2048-2056 ◽  
Author(s):  
Yoonjin Kim ◽  
Song Jun Doh ◽  
Gyu Dong Lee ◽  
Chaehwa Kim ◽  
Jung Nam Im


2021 ◽  
Author(s):  
Wenjun Jiang ◽  
Zuoyao Huang ◽  
Weixiang Min ◽  
Hao Zhang

Abstract In the current study a drug delivering bilayer porous/nanofibrous wound dressing was developed using a combination of electrospinning and freeze-drying methods. The wound dressings were prepared by lyophilization of 1:1 weight ratios of calcium alginate and carboxymethyl cellulose (CMC) solutions. Drug delivering nanofibrous sheets were fabricated by electrospinning of polyvinyl alcohol (PVA) solution incorporated with 1%,3%,5%, and 10% of Propionyl-L-carnitine. The dressings were studied regarding their microstructure, swelling capacity, mechanical strength, surface wettability, water vapor permeability, drug release profile, in vitro degradation, cell viability assay, hemocompatibility, porosity measurement, microbial penetration assay, and protein adsorption assay. Based on in vitro studies, PVA sheets loaded with 5% Propionyl-L-carnitine was chosen for the preparation of wound dressings. The healing potential of the produced constructs was studied in rat model of diabetic wound. Our results showed that the drug delivering dressings demonstrated significantly higher wound closure and better histological regeneration compared to drug free constructs and sterile gauze. Our results suggest potential applicability of Propionyl-L-carnitine delivering Calcium Alginate/CMC/PVA dressing for the treatment of diabetic wounds in clinic.



2020 ◽  
Vol 1009 ◽  
pp. 3-8
Author(s):  
Narumol Kreua-Ongarjnukool ◽  
Saowapa Thumsing Niyomthai ◽  
Kodchaporn Sarodom ◽  
Thitithip Lothong ◽  
Nopparuj Soomherun

Antibacterial wound dressing has an important key in an infection in traumatic and surgical wounds. However, the antibacterial wound dressing is high cost and few domestic medical productions. The aim of this study is to prepare a wound dressing hydrogel from hybrid gelatin/carboxymethyl cellulose (Gel/CMC) hydrogel crosslinked with citric acid at different Gel: CMC ratios of 1:1, 1:2, 1:3, and 1:4 by solvent casting. The gel fractions and swelling of 6.0%w/v CuSO4 loading hybrid Gel/CMC hydrogel (Cu-Gel/CMC hydrogel) were a maximum of about 44% to 53% and 85% to 245%, respectively. The results showed that the 1:1 Gel: CMC of hydrogel produce was the most suitable condition due to its good gel fractions and swelling behavior. The cumulative Cu2+ release was a maximum of about 45% in 7 days. The hybrid Cu-Gel/CMC hydrogel showed the zone of inhibition of Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) about 16 mm and 19 mm, sequentially. The research provided that the hybrid Cu-Gel/CMC hydrogel has the potential to use in medical applications.



2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Tina Maver ◽  
Lidija Gradišnik ◽  
Dragica Maja Smrke ◽  
Karin Stana Kleinschek ◽  
Uroš Maver


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