scholarly journals Body Weight and Body Mass Index Influence Bone Mineral Density in Late Adolescence in a Two‐Year Follow‐Up Study. The Tromsø Study: Fit Futures

JBMR Plus ◽  
2019 ◽  
Vol 3 (9) ◽  
Author(s):  
Ole Andreas Nilsen ◽  
Luai Awad Ahmed ◽  
Anne Winther ◽  
Tore Christoffersen ◽  
Gyrd Thrane ◽  
...  
2014 ◽  
Vol 3 (4) ◽  
pp. 276
Author(s):  
Biplob Chowdhury ◽  
Brajanath Kundu

Risk factors for the prediction of osteoporosis are an important and cost effective method since osteoporosis is a silent disease. The purpose of the study was to evaluate the associations between weight, body mass index (BMI), the Osteoporosis Self-Assessment Tool (OST), and bone mineral density (BMD) in postmenopausal women in India. In this cross sectional study, 90 postmenopausal women aged 45–85 years who had given consent participated and the study was conducted between April, 2012 and May, 2013. BMD was measured by ultrasound bone densitometry at calcaneal site. Linear regression multivariate models were used to examine the associations with weight, BMI, OST, and BMD. Body weight, BMI, and OST had almost similar overall performance in their ability to classify women with BMD T-score ≤−2.5. Regression results showed that the linear combination of three independent variables BMI, OST and body weight. BMI predicted 65.7% of the variance in BMD, <em>R</em><sup>2</sup> = .657, <em>R</em><em><sup>2</sup></em><sup> </sup>adjusted = .609, (F=21.295, p&lt;.000). The strongest predictor of low BMD was BMI. BMI showed significant association with BMD with a correlation of .846. Low weight and BMI predict osteoporosis and are associated with increased risks in postmenopausal women. The negative impact of low body weight on bone health should be more widely recognized.


2014 ◽  
Vol 3 (4) ◽  
pp. 276
Author(s):  
Biplob Chowdhury ◽  
Brajanath Kundu

Risk factors for the prediction of osteoporosis are an important and cost effective method since osteoporosis is a silent disease. The purpose of the study was to evaluate the associations between weight, body mass index (BMI), the Osteoporosis Self-Assessment Tool (OST), and bone mineral density (BMD) in postmenopausal women in India. In this cross sectional study, 90 postmenopausal women aged 45–85 years who had given consent participated and the study was conducted between April, 2012 and May, 2013. BMD was measured by ultrasound bone densitometry at calcaneal site. Linear regression multivariate models were used to examine the associations with weight, BMI, OST, and BMD. Body weight, BMI, and OST had almost similar overall performance in their ability to classify women with BMD T-score ≤−2.5. Regression results showed that the linear combination of three independent variables BMI, OST and body weight. BMI predicted 65.7% of the variance in BMD, <em>R</em><sup>2</sup> = .657, <em>R</em><em><sup>2</sup></em><sup> </sup>adjusted = .609, (F=21.295, p&lt;.000). The strongest predictor of low BMD was BMI. BMI showed significant association with BMD with a correlation of .846. Low weight and BMI predict osteoporosis and are associated with increased risks in postmenopausal women. The negative impact of low body weight on bone health should be more widely recognized.


2015 ◽  
Vol 27 (4) ◽  
pp. 259 ◽  
Author(s):  
Sylejman Rexhepi ◽  
Elton Bahtiri ◽  
Mjellma Rexhepi ◽  
Vjollca SahatciuMeka ◽  
Blerta Rexhepi

Author(s):  
Yin-Ting Wu ◽  
Bang-Gee Hsu ◽  
Chih-Hsien Wang ◽  
Yu-Li Lin ◽  
Yu-Hsien Lai ◽  
...  

Recent evidence has indicated that fibroblast growth factor 21 (FGF21) regulates longitudinal bone growth, with increased FGF21 levels leading to bone loss. The present study evaluated the relationship between bone mineral density (BMD) and serum FGF21 levels in patients undergoing hemodialysis (HD). We analyzed blood samples from 95 patients undergoing HD and measured BMD using dual-energy X-ray absorptiometry of the lumbar vertebrae (L2–L4). Serum FGF21 concentrations were determined using a commercially available enzyme-linked immunosorbent assay kit. Thirteen (11.6%) patients were found to have osteoporosis, 27 (28.4%) osteopenia, and 57 patients had normal BMD. Advanced age and decreased body mass index, height, body weight, waist circumference, and triglyceride level were associated with lower lumbar T-scores, as were increased alkaline phosphatase, urea reduction rate, fractional clearance index for urea, and FGF21 levels. Low log-FGF21, increased body mass index, increased pre-HD body weight, and increased logarithmically transformed triglycerides (log-TG) were found to be significantly and independently associated with lumbar BMD by multivariate forward stepwise linear regression analysis with adjustment for significant confounders. We conclude that high serum FGF21 level is negatively associated with BMD in patients undergoing HD.


2020 ◽  
Vol 14 (3) ◽  
pp. S71
Author(s):  
L. Cherukuri ◽  
A. Kinninger ◽  
D. Birudaraju ◽  
S. Lakshmanan ◽  
D. Li ◽  
...  

Author(s):  
Avani Goyal ◽  
Veena Ganju Malla

Background: Osteoporosis is a common health problem that affects postmenopausal females, leading to increased susceptibility to fractures. Body mass index (BMI) has been shown to be an important predictor of bone mineral density (BMD) with increased body weight correlating with positive influence on bone metabolism. Low BMI predisposes postmenopausal females to rapid bone loss and low bone mass, crucial in the pathogenesis of osteoporosis. However, a specific BMI value chart to accurately predict osteoporosis remains to be fully established. The present study aimed to investigate the relationship of BMI and BMD in postmenopausal Indian females.Methods: 90 healthy postmenopausal females with 1-5 years of menopause were enrolled in the study. Subjects were categorized according to their BMI into normal, overweight and obese. BMD was assessed using dual energy X-ray absorptiometry (DEXA) scan at L1-L4 vertebrae and femoral neck and expressed as T-scores. Quantitative variables were compared using ANOVA/Kruskal Wallis Test.Results: Bone mineral density was significantly higher in the obese group as compared to normal BMI group at both lumbar spine (p=0.001) and femoral neck (p=0.001). BMD at lumbar spine was lower than that at femoral neck across all the three groups of BMI.Conclusions: BMI and body weight are important factors affecting BMD. Postmenopausal females with low BMI are more likely to have osteopenia and osteoporosis and are thus at an increased risk of pathological fractures. Routine BMD monitoring in postmenopausal females with low BMI may be necessary to initiate early clinical interventions for osteoporosis.


2005 ◽  
Vol 351 (1-2) ◽  
pp. 161-168 ◽  
Author(s):  
Ni Zhong ◽  
Xian-Ping Wu ◽  
Zhang-Rong Xu ◽  
Ai-Hong Wang ◽  
Xiang-Hang Luo ◽  
...  

2020 ◽  
Author(s):  
Pejicic Snjezana Popovic ◽  
Nina Pejicic ◽  
Aleksandra Grbic

Author(s):  
Lavanya Cherukuri ◽  
April Kinninger ◽  
Divya Birudaraju ◽  
Suvasini Lakshmanan ◽  
Dong Li ◽  
...  

2008 ◽  
Vol 19 (6) ◽  
pp. 839-847 ◽  
Author(s):  
A. C. Heijckmann ◽  
M. Drent ◽  
B. Dumitrescu ◽  
J. De Vries ◽  
A. C. Nieuwenhuijzen Kruseman ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document