Timely Degradation of Wip1 Phosphatase by APC/C Activator Protein Cdh1 is Necessary for Normal Mitotic Progression

Ho-Chang Jeong; Na-Yeon Gil; Ho-Soo Lee; Seung-Ju Cho; Kyungtae Kim; Kwang-Hoon Chun; Hyeseong Cho; Hyuk-Jin Cha

doi:10.1002/jcb.25114

Timely Degradation of Wip1 Phosphatase by APC/C Activator Protein Cdh1 is Necessary for Normal Mitotic Progression

Journal of Cellular Biochemistry ◽

10.1002/jcb.25114 ◽

2015 ◽

Vol 116 (8) ◽

pp. 1602-1612 ◽

Cited By ~ 10

Author(s):

Ho-Chang Jeong ◽

Na-Yeon Gil ◽

Ho-Soo Lee ◽

Seung-Ju Cho ◽

Kyungtae Kim ◽

...

Keyword(s):

Mitotic Progression ◽

Activator Protein ◽

Wip1 Phosphatase

Cytokine synergy, collagenases and cartilage collagen breakdown

Biochemical Society Symposium ◽

10.1042/bss0700125 ◽

2003 ◽

Vol 70 ◽

pp. 125-133 ◽

Cited By ~ 7

Author(s):

Tim E. Cawston ◽

Jenny M. Milner ◽

Jon B. Catterall ◽

Andrew D. Rowan

Keyword(s):

Matrix Metalloproteinases ◽

Inflammatory Cytokines ◽

Activator Protein 1 ◽

Activator Protein ◽

And Cartilage ◽

Pro Inflammatory Cytokines

We have investigated proteinases that degrade cartilage collagen. We show that pro-inflammatory cytokines act synergistically with oncastatin M to promote cartilage collagen resorption by the up-regulation and activation of matrix metalloproteinases (MMPs). The precise mechanisms are not known, but involve the up-regulation of c-fos, which binds to MMP promoters at a proximal activator protein-1 (AP-1) site. This markedly up-regulates transcription and leads to higher levels of active MMP proteins.

Activator protein-1 is necessary for angiotensin-II stimulation of human adrenocorticotropin receptor gene transcription

European Journal of Biochemistry ◽

10.1046/j.1432-1033.2001.02055.x ◽

2001 ◽

Vol 268 (6) ◽

pp. 1802-1810

Author(s):

Danielle Naville ◽

Estelle Bordet ◽

Marie-Claude Berthelon ◽

Philippe Durand ◽

Martine Begeot

Keyword(s):

Angiotensin Ii ◽

Gene Transcription ◽

Receptor Gene ◽

Activator Protein 1 ◽

Activator Protein ◽

Stimulation Of

Die epigenetische Regulation von Transcription factor activator protein-2 epsilon (TFAP2E) führt via Dickkopf homolog 4 zur Chemoresistenz von 5-Fluoruracil beim kolorektalen Karzinom

Zeitschrift für Gastroenterologie ◽

10.1055/s-0030-1263599 ◽

2010 ◽

Vol 48 (08) ◽

Author(s):

M Tänzer ◽

B Balluff ◽

R Tetzner ◽

E Burgermeister ◽

A Reinacher Schick ◽

...

Keyword(s):

Transcription Factor ◽

Activator Protein ◽

Activator Protein 2

Faculty Opinions recommendation of Inactivation of the Wip1 phosphatase inhibits mammary tumorigenesis through p38 MAPK-mediated activation of the p16(Ink4a)-p19(Arf) pathway.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1017697.207703 ◽

2004 ◽

Author(s):

Francesc Posas

Keyword(s):

P38 Mapk ◽

Mammary Tumorigenesis ◽

Wip1 Phosphatase ◽

P16 Ink4a

Faculty Opinions recommendation of Timing and checkpoints in the regulation of mitotic progression.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1020067.241477 ◽

2004 ◽

Author(s):

Bruce McEwen

Keyword(s):

Mitotic Progression

Faculty Opinions recommendation of Structural basis for cAMP-mediated allosteric control of the catabolite activator protein.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1159419.619779 ◽

2009 ◽

Author(s):

Peter Artymiuk

Keyword(s):

Structural Basis ◽

Allosteric Control ◽

Catabolite Activator Protein ◽

Activator Protein

Faculty Opinions recommendation of Gonadotropin-releasing hormone pulse sensitivity of follicle-stimulating hormone-beta gene is mediated by differential expression of positive regulatory activator protein 1 factors and corepressors SKIL and TGIF1.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.12586956.13825054 ◽

2011 ◽

Author(s):

Mone Zaidi ◽

Tony Yuen

Keyword(s):

Differential Expression ◽

Follicle Stimulating Hormone ◽

Gonadotropin Releasing Hormone ◽

Activator Protein 1 ◽

Releasing Hormone ◽

Activator Protein ◽

Beta Gene ◽

Stimulating Hormone

Faculty Opinions recommendation of Nintedanib modulates surfactant protein-D expression in A549 human lung epithelial cells via the c-Jun N-terminal kinase-activator protein-1 pathway.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.727167063.793527367 ◽

2017 ◽

Author(s):

Martin Aringer

Keyword(s):

Epithelial Cells ◽

Human Lung ◽

Surfactant Protein ◽

Lung Epithelial Cells ◽

Surfactant Protein D ◽

Activator Protein 1 ◽

Activator Protein ◽

Lung Epithelial ◽

Human Lung Epithelial Cells

Faculty Opinions recommendation of Mitotic progression following DNA damage enables pattern recognition within micronuclei.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.727856929.793535204 ◽

2017 ◽

Author(s):

Junjie Chen

Keyword(s):

Pattern Recognition ◽

Dna Damage ◽

Mitotic Progression

Faculty Opinions recommendation of WIP1 phosphatase suppresses the DNA damage response during G2/prophase arrest in mouse oocytes.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.733195347.793548972 ◽

2018 ◽

Author(s):

Keith Jones ◽

Jessica Sanders

Keyword(s):

Dna Damage ◽

Dna Damage Response ◽

Mouse Oocytes ◽

Wip1 Phosphatase ◽

Damage Response