Synthesis of coumarin derivatives in a microfluidic flow system employing the Pechmann condensation: A case study

Author(s):  
Ling‐Kang Liu ◽  
Jhao‐Hong Deng ◽  
Yang‐Ming Guo
2016 ◽  
Vol 20 (7) ◽  
pp. 798-828 ◽  
Author(s):  
Abhay S. Zambare ◽  
Firoz A. Kalam Khan ◽  
Sureshchandra P. Zambare ◽  
Shantanu D. Shinde ◽  
Jaiprakash N. Sangshetti

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Saeed Khodabakhshi

Various coumarin derivatives have been efficiently synthesized via barium dichloride-catalyzed Pechmann condensation reaction of various phenols and β-keto esters under solvent-free conditions. This novel and inexpensive method has advantages such as short reaction times, excellent product yields, and avoidance of organic solvents in agreement with green chemistry principles.


2018 ◽  
Vol 204 ◽  
pp. 02009 ◽  
Author(s):  
Dani Yuniawan ◽  
P.P Aang Fajar ◽  
Samsudin Hariyanto ◽  
Romi Setiawan

Currently Mergan 4-way intersection is one of intersection that have most traffic dense in Malang City, East Java - Indonesia. This research implement simulation method in order to give several solution option to manage the traffic queue in Mergan 4-way intersection. Simulation method is conducted with several phase, from problem identification up to verification and validation also scenario simulation. Arena Simulation software v.14 is chosen as the tool to modeling the traffic queue line. The research outcome give several solution through Traffic Light 2 simulation scenario. With this simulation scenario, the traffic flow system simulation can be run with fewer queues of vehicles.


2018 ◽  
Vol 167 ◽  
pp. 01005
Author(s):  
Xiao-Yu Xie ◽  
Sheng-Xi Fan

In the view of Chinese traditional twenty-four solar terms, the circulation of various substances in the material flow system of base production and life is systematically analyzed, and on the basis of the existing system problem point, as well as by combining with the concept of the twenty-four solar terms and the system design method, the author reconstructs each subsystem of the base material flow system, moreover, the author eventually connects the subsystems and reconstructs a material flow system conforming to the traditional Chinese solar terms and conforming to the requirements of ecological sustainability.


2016 ◽  
Vol 132 ◽  
pp. 98-107 ◽  
Author(s):  
Pi-Cheng Chen ◽  
Ming-Cheng Chiu ◽  
Hwong-wen Ma
Keyword(s):  

2021 ◽  
Vol 7 (1) ◽  
pp. 62-68
Author(s):  
Juliana Jumal ◽  
Norhanis Sakinah

Coumarin and its derivatives represent one of the most active curriculums of compound possessing a broad spectrum of biological activity along with other applications such as insecticide and fragrance. There are various methodologies developed for the synthesis of coumarins. Classical routes to coumarins include Pechmann condensation, Knoevenagel condensation, Perkin reaction, and Wittig condensation reactions. Researchers have carried out adjustments and improvements to increase the efficacy and overcome the limitations from the classical route. In this review outline, coumarin derivatives were characterized by using FTIR and Hydrogen NMR spectroscopy. This review paper focuses on various synthesis and characterization techniques to analyze coumarin derivatives and their potential application in various fields.


2018 ◽  
Vol 27 (2) ◽  
pp. 717-730 ◽  
Author(s):  
Masahiko Ono ◽  
Isao Machida ◽  
Reo Ikawa ◽  
Takafumi Kamitani ◽  
Koichi Oyama ◽  
...  

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