scholarly journals Barium Dichloride as a Powerful and Inexpensive Catalyst for the Pechmann Condensation without Using Solvent

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Saeed Khodabakhshi
Keyword(s):  
Green Chemistry ◽  
Organic Solvents ◽  
Condensation Reaction ◽  
Reaction Times ◽  
Solvent Free ◽  
Coumarin Derivatives ◽  
Inexpensive Method ◽  
Keto Esters ◽  
Pechmann Condensation ◽  
Solvent Free Conditions

Various coumarin derivatives have been efficiently synthesized via barium dichloride-catalyzed Pechmann condensation reaction of various phenols and β-keto esters under solvent-free conditions. This novel and inexpensive method has advantages such as short reaction times, excellent product yields, and avoidance of organic solvents in agreement with green chemistry principles.

scholarly journals Easy Access to Coumarin Derivatives Using Alumina Sulfuric Acid as an Efficient and Reusable Catalyst under Solvent-Free Conditions

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Ali Amoozadeh ◽  
Majid Ahmadzadeh ◽  
Eskandar Kolvari
Keyword(s):  
Sulfuric Acid ◽  
Condensation Reaction ◽  
Solvent Free ◽  
Easy Access ◽  
Reusable Catalyst ◽  
Coumarin Derivatives ◽  
Free Condition ◽  
Pechmann Condensation ◽  
Solvent Free Condition ◽  
Solvent Free Conditions

A new and efficient condition for the use of alumina sulfuric acid (ASA) as a heterogeneous catalyst in the Pechmann condensation reaction in solvent-free condition for the formation of coumarins has been reported.

scholarly journals One Pot, Solvent-Free Synthesis of Substituted 3,4-Dihydropyrimidin-2(1H)-Ones/Thiones under Microwave Irradiation (CEM) Using Reusable Nickel Nanoparticles

2015 ◽  
Vol 50 ◽  
pp. 17-25 ◽  
Author(s):  
Mayur K. Vekariya ◽  
Rajesh H. Vekariya ◽  
Nirav N. Barot ◽  
Tauhid A. Shaikh ◽  
Harjinder Kaur ◽  
...  
Keyword(s):  
Microwave Irradiation ◽  
Nickel Nanoparticles ◽  
Condensation Reaction ◽  
Solvent Free ◽  
High Yield ◽  
One Pot ◽  
Mass Spectral ◽  
Keto Esters ◽  
Aryl Aldehydes ◽  
Solvent Free Conditions

A library of 3,4-dihydropyrimidin-2(1H)-ones/thiones derivatives were synthesized via Biginelli condensation reaction of β-keto esters, aryl aldehydes and urea/thiourea under solvent-free conditions utilizing nickel nanoparticles under microwave irradiation (CEM Discover). The structures of the all compounds were elucidated with the aid of elemental analysis, IR, 1H-NMR and Mass spectral data. Nickel nanoparticles can be recovered and reused five times without loss of their efficiency. Short reaction time, high yield of products and simple workup procedure, solvent-free conditions and reusability of the catalyst are the superior features of this protocol.

An Efficient Solvent-Free Synthesis of Bis(2-Tetrahydrobenzofuranyl)Alkanes Catalyzed by H2SO4•SiO2

2014 ◽  
Vol 1033-1034 ◽  
pp. 49-52
Author(s):  
Fan Zhang ◽  
Lu Lu Xiao ◽  
Lei Jin ◽  
Wen Bin Wang ◽  
Nian Yu Huang
Keyword(s):  
Good Yield ◽  
Functional Group ◽  
Condensation Reaction ◽  
Reaction Times ◽  
Solvent Free ◽  
Environmentally Benign ◽  
Simple Operation ◽  
Solvent Free Conditions ◽  
Benign Nature ◽  
Solvent Free Synthesis

A series of bis (2-tetrahydrobenzofuranyl) alkanes in good yield under solvent-free conditions from differently aromatic substituted aldehydes and 3-methyl-6,7-dihydrobenzofuran-4(5H)-one in the presence of H2SO4•SiO2 as catalyst at 90oC. Their structures were characterized by NMR, IR and ESI-MS. The proposed mechanism for the H2SO4•SiO2-catalyzed condensation reaction have been discussed in the work. This versatile approach has the advantages of broad functional group compatibility, short reaction times, simple operation and environmentally benign nature.

scholarly journals Chromium (III) Nitrate Nonahydrate: An Environmentally Benign and Efficient Heterogeneous Catalyst for Facile One-Pot Biginelli Synthesis of 3,4-Dihydropyrimidin-2-(1H)-One/Thione Derivatives Under Solvent-Free Conditions

2016 ◽  
Vol 24 (1) ◽  
pp. 29-42
Author(s):  
Mojtaba Lashkari ◽  
Reza Heydari ◽  
Farzaneh Mohamadpour
Keyword(s):  
Reaction Times ◽  
Aromatic Aldehydes ◽  
Solvent Free ◽  
Environmentally Benign ◽  
One Pot ◽  
Keto Esters ◽  
H Nmr ◽  
Solvent Free Conditions ◽  
Nitrate Nonahydrate ◽  
The One

Abstract The use of chromium(III) nitrate nonahydrate (Cr(NO3)3·9H2O) as an efficient, mild and economical catalyst for the one-pot three-component Biginelli synthesis of 3,4-dihydropyrimidin-2-(1H)-one/thione derivatives in the reaction between β-keto esters (methyl or ethyl acetoacetate), aromatic aldehydes (benzaldehye derivatives) and urea or thiourea under thermal and solvent-free conditions with good yields and short reaction times is reported. The most benefits of this synthetic method include the use of an efficient, eco-friendly, inexpensive and non-toxic catalyst, as well as the solvent-free conditions. All products were characterized by 1H NMR spectroscopy and melting point determination.

scholarly journals H2SO4-Silica Catalyzed One-Pot and Efficient Synthesis of Dihydropyrimidinones Under Solvent-Free Conditions

2011 ◽  
Vol 8 (s1) ◽  
pp. S462-S466 ◽  
Author(s):  
Seied Ali Pourmousavi ◽  
Maryam Hasani
Keyword(s):  
Condensation Reaction ◽  
Biginelli Reaction ◽  
Reaction Times ◽  
Solvent Free ◽  
New Method ◽  
Efficient Synthesis ◽  
Reaction Conditions ◽  
One Pot ◽  
Solvent Free Conditions ◽  
High Yields

H2SO4-Silica efficiently catalyzes the three-component condensation reaction of aldehydes, 1,3-dicarbonyl compounds and urea/thiourea under solvent free conditions to afford the corresponding dihydropyrimidinones and thio-derivatives in high yields. Compared to the classical Biginelli reaction conditions, this new method consistently has the advantage of giving good yields and requiring short reaction times.

scholarly journals CES as an Efficient Natural Catalyst for Synthesis of Schiff Bases under Solvent-Free Conditions: An Innovative Green Approach

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Suresh Patil ◽  
S. D. Jadhav ◽  
S. K. Shinde
Keyword(s):  
Aromatic Amines ◽  
Condensation Reaction ◽  
Reaction Times ◽  
Aromatic Aldehydes ◽  
Solvent Free ◽  
Schiff Base Ligands ◽  
Green Approach ◽  
Good Product ◽  
Economic Method ◽  
Solvent Free Conditions

A mild and efficient method has been reported for the preparation of Schiff base ligands through the condensation reaction of various aromatic aldehydes with substituted aromatic amines in the presence of CES (calcined eggshell) as a heterogeneous catalyst under solvent-free conditions. The advantages of this ecofriendly, economic method are simplicity of the reaction procedure, moderate to good product yields, and very short reaction times.

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