scholarly journals Evaluation of the serum levels of Mannose binding lectin‐2, tenascin‐C, and total antioxidant capacity in patients with coronary artery disease

2021 ◽  
Author(s):  
Hamed Mehri ◽  
Naser Aslanabadi ◽  
Alireza Nourazarian ◽  
Behrouz Shademan ◽  
Fatemeh khaki‐khatibi
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
Serum Levels ◽  
Mannose Binding Lectin ◽  
Mannose Binding ◽  
Total Antioxidant ◽  
Artery Disease ◽  
Binding Lectin

scholarly journals Serum Levels of Mannose-Binding Lectin and the Risk of Future Coronary Artery Disease in Apparently Healthy Men and Women

2006 ◽  
Vol 26 (10) ◽  
pp. 2345-2350 ◽  
Author(s):  
Tymen T. Keller ◽  
Sander I. van Leuven ◽  
Marijn C. Meuwese ◽  
Nicholas J. Wareham ◽  
Robert Luben ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Serum Levels ◽  
Mannose Binding Lectin ◽  
Men And Women ◽  
Healthy Men ◽  
Mannose Binding ◽  
Artery Disease ◽  
Binding Lectin ◽  
Apparently Healthy

scholarly journals Prospective, case-controlled study evaluating serum concentration of sirtuin-1 and mannose-binding lectin in patients with and without periodontal and coronary artery disease

2020 ◽  
Vol 11 ◽  
pp. 204062232091962
Author(s):  
Pérola Michelle Vasconcelos Caribé ◽  
Cristina Cunha Villar ◽  
Guiseppe Alexandre Romito ◽  
Júlio Yoshio Takada ◽  
Ana Paula Pacanaro ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Serum Concentration ◽  
Mannose Binding Lectin ◽  
Sirtuin 1 ◽  
Controlled Study ◽  
Enzyme Linked Immunosorbent Assay ◽  
Mannose Binding ◽  
Artery Disease ◽  
Binding Lectin

Background: Atherosclerosis and periodontal disease (PD) are inflammatory diseases that have been shown in studies to have a direct association. Mannose-binding lectin (MBL) is an immune system protein that binds to periodontal pathogens favoring phagocytosis. Conversely, increased serum sirtuin-1 (SIRT1) concentration reduces the inflammatory process. Methods: This was a prospective, case-controlled study that analyzed serum concentration of biomarkers in patients with or without coronary artery disease (CAD) and PD. A total of 78 patients were evaluated: 20 healthy individuals, 18 patients with CAD, 20 patients with PD, and 20 patients with both PD and CAD. Clinical and laboratory characteristics were analyzed before and after nonsurgical treatment of PD and also at two equivalent times in patients without PD. Serum MBL and SIRT1 concentration were analyzed by enzyme-linked immunosorbent assay. Results: A negative correlation was observed between changes in serum concentration of MBL and SIRT1 ( r = −0.30; p = 0.006). Comparison between pre- and post-treatment of PD showed a reduction in MBL levels (886.27 ± 906.72 versus 689.94 ± 808.36; p = 0.002) and an increase in SIRT1 values (0.80 ± 1.01 versus 1.49 ± 1.55; p = 0.005) in patients with PD and without CAD. The same result was observed in patients with PD and CAD for MBL and SIRT1, respectively, of 1312.43 ± 898.21 versus 1032.90 ± 602.52 ( p = 0.010) and 1.32 ± 1.0 versus 1.82 ± 1.75 ( p = 0.044). Conclusion: PD treatment reduced MBL serum concentration and increased SIRT1 serum concentration in patients with and without CAD.

scholarly journals Relationship between total antioxidant capacity and the severity of coronary artery disease

2012 ◽  
Vol 3 (1) ◽  
Author(s):  
Yusuf Selcoki ◽  
Murat Aydın ◽  
Yunus Nazlı ◽  
Kadir Serkan Yalçın ◽  
Metin Canbal ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
Total Antioxidant ◽  
Artery Disease

Mannose binding lectin 2 haplotypes do not affect the progression of coronary atherosclerosis in men with proven coronary artery disease treated with pravastatin

2011 ◽  
Vol 215 (1) ◽  
pp. 125-129 ◽  
Author(s):  
Arash Alipour ◽  
Manuel Castro Cabezas ◽  
Jan Willem F. Elte ◽  
Joan-Carles Vallvé ◽  
Josep Ribalta ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Coronary Atherosclerosis ◽  
Mannose Binding Lectin ◽  
Mannose Binding ◽  
Artery Disease ◽  
Binding Lectin

scholarly journals Association of obstructive sleep apnea with homocystein, nitric oxide and total antioxidant capacity levels in patients with or without coronary artery disease

2014 ◽  
Vol 62 (3) ◽  
pp. 207-214
Author(s):  
Ebru Ortaç Ersoy ◽  
Hikmet Fırat ◽  
Sevgi Akaydın ◽  
Yeşim Özkan ◽  
Mine Durusu ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Coronary Artery Disease ◽  
Obstructive Sleep Apnea ◽  
Coronary Artery ◽  
Sleep Apnea ◽  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
Obstructive Sleep ◽  
Total Antioxidant ◽  
Artery Disease

Antioxidant status and risk of coronary artery disease

2019 ◽  
Vol 49 (4) ◽  
pp. 700-712 ◽  
Author(s):  
Shokoofeh Talebi ◽  
Zamzam Paknahad ◽  
Mohammad Hashemi ◽  
Akbar Hasanzadeh
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Content Type ◽  
Total Antioxidant ◽  
Artery Disease ◽  
Artery Obstruction

Purpose Coronary artery disease (CAD) is developed by an insufficient supply of oxygen-rich blood to the myocardium. Recent studies have shown that increased oxidative stress has implicated in the pathogenesis of coronary atherosclerosis. Anxiety and CAD have a mutual relationship, as the effect of long-lasting anxiety on atherosclerosis and CAD is well known. The purpose of this study is to investigate the relationship between dietary / serum total antioxidant capacity and CAD. Design/methodology/approach A total of 160 male patients were enrolled in this cross-sectional study. Diagnosis and analysis of angiograms were performed visually by a cardiologist. The subjects were categorized into CAD− (coronary artery obstruction <75 per cent) and CAD+ (coronary artery obstruction ≥ 75 per cent) groups. Anthropometric indices, blood pressure, blood sugar and lipid profile and physical activity (PA) were assessed. Information about anxiety was obtained by Spielberger questionnaire. Dietary total antioxidant capacity (TAC) was obtained by using a semi-quantitative food frequency questionnaire and an oxygen radical absorbance capacity of selected foods. Findings Mean of dietary TAC was significantly lower in CAD+ than CAD− group (P < 0.001). However, there was not any significant differences about serum TAC (P = 0.28). The mean of body mass index (BMI) (P = 0.04) and triglyceride (TG) level (P = 0.03) and the frequency of smoking (P = 0.03) were significantly higher in the CAD+ than the CAD− group. There was no significant relationship between CAD with apparent (P = 0.33) and hidden anxiety level (P = 0.16). Confounding factors such as smoking and medications were adjusted. Research limitations/implications This study had certain limitations. Being a single center cross-sectional design does not permit analysis of causal relationships; the sample size was geographically limited. The authors could not exclude the medication of patients, which could affect the total antioxidant capacity levels. Measurement error in self-reported dietary consumption may results misclassification of exposure. Practical implications A diet high in total antioxidant capacity is inversely associated with CAD. Serum TAC does not vary between men with and without CAD when confounders including age, BMI, TG, smoking, SBP, DBP, energy intake, PA, HDL-C, LDL-C, T-C, FBS, family history of CAD, education and anxiety are taken into consideration. Social implications High consumption of vegetables and fruits may play a major role in the prevention of CAD. Originality/value The study was approved by the ethics committee of Isfahan University of Medical Sciences (No:394888).

scholarly journals Association ofChlamydia pneumoniaeWith Coronary Artery Disease and Its Progression Is Dependent on the Modifying Effect of Mannose-Binding Lectin

Circulation ◽  
2002 ◽  
Vol 106 (9) ◽  
pp. 1071-1076 ◽  
Author(s):  
Szabolcs Rugonfalvi-Kiss ◽  
Valéria Endrész ◽  
Hans O. Madsen ◽  
Katalin Burián ◽  
Jenô Duba ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Mannose Binding Lectin ◽  
Mannose Binding ◽  
Modifying Effect ◽  
Artery Disease ◽  
Binding Lectin
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