Platelet-activating factor secreted by DDAVP-treated monocytes mediates von willebrand factor release from endothelial cells

1993 ◽  
Vol 154 (3) ◽  
pp. 496-505 ◽  
Author(s):  
S. Hashemi ◽  
D. S. Palmer ◽  
M. T. Aye ◽  
P. R. Ganz
Keyword(s):  
Endothelial Cells ◽  
Von Willebrand Factor ◽  
Platelet Activating Factor ◽  
Von Willebrand ◽  
Willebrand Factor ◽  
Factor Release

scholarly journals Tspan18 is a novel regulator of the Ca2+ channel Orai1 and von Willebrand factor release in endothelial cells

Haematologica ◽  
2018 ◽  
Vol 104 (9) ◽  
pp. 1892-1905 ◽  
Author(s):  
Peter J. Noy ◽  
Rebecca L. Gavin ◽  
Dario Colombo ◽  
Elizabeth J. Haining ◽  
Jasmeet S. Reyat ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Von Willebrand Factor ◽  
Von Willebrand ◽  
Willebrand Factor ◽  
Factor Release

Cyclosporine And Cremaphor Modulate Von Willebrand Factor Release From Cultured Human Endothelial Cells

1993 ◽  
Vol 56 (5) ◽  
pp. 1218-1222 ◽  
Author(s):  
Peter Collins ◽  
Martin Wilkie ◽  
Khalid Razak ◽  
Stewart Abbot ◽  
Suzanne Harley ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Von Willebrand Factor ◽  
Human Endothelial Cells ◽  
Von Willebrand ◽  
Willebrand Factor ◽  
Factor Release

Von Willebrand Factor Release and P-Selectin Expression Is Stimulated by Thrombin and Trypsin but not IL-1 in Cultured Human Endothelial Cells

1993 ◽  
Vol 70 (02) ◽  
pp. 346-350 ◽  
Author(s):  
Peter W Collins ◽  
Marion G Macey ◽  
Mary R Cahill ◽  
Adrian C Newland
Keyword(s):  
Flow Cytometry ◽  
Endothelial Cells ◽  
Cell Membrane ◽  
Von Willebrand Factor ◽  
Surface Expression ◽  
Monocyte Adhesion ◽  
Human Endothelial Cells ◽  
Von Willebrand ◽  
Willebrand Factor ◽  
Factor Release

SummaryThe stimulated release of von Willebrand factor (vWF) from endothelial cells by secretagogues such as thrombin is associated with the translocation of Weibel-Palade bodies to the cell membrane and the surface expression of P-selectin (also known as GMP 140, PADGEM and CD 62). P-selectin, which is stored in Weibel-Palade bodies, is a neutrophil and monocyte adhesion molecule important in the initiation of inflammation.We have developed a simple assay for the detection of P-selectin on endothelial cells using indirect immunofluorescence and flow cytometry and have confirmed that this is temporally related to vWF release. The assay has been used to demonstrate that IL-1 does not cause Weibel-Palade body degranulation but that trypsin does. This has implications for the use of passaged endothelial cells in the study of vWF release and the assay has numerous possible applications in study of mechanisms of stimulated vWF release.

606: FERRITIN PROMOTES VON WILLEBRAND FACTOR RELEASE FROM ENDOTHELIAL CELLS VIA PKC SIGNALING

2016 ◽  
Vol 44 (12) ◽  
pp. 228-228
Author(s):  
Dalia Bashir ◽  
Trung Nguyen ◽  
Qi Da ◽  
Miguel Cruz ◽  
Carl Allen ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Von Willebrand Factor ◽  
Pkc Signaling ◽  
Von Willebrand ◽  
Willebrand Factor ◽  
Factor Release
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