Adrenal–kidney–gonad complex measurements may not predict gonad-specific changes in gene expression patterns during temperature-dependent sex determination in the red-eared slider turtle (Trachemys scripta elegans)

2007 ◽  
Vol 307A (8) ◽  
pp. 463-470 ◽  
Author(s):  
Mary Ramsey ◽  
David Crews
Keyword(s):  
Gene Expression ◽  
Sex Determination ◽  
Expression Patterns ◽  
Trachemys Scripta ◽  
Gene Expression Patterns ◽  
Temperature Dependent ◽  
Trachemys Scripta Elegans ◽  
Slider Turtle

scholarly journals Transvection regulates the sex-biased expression of a fly X-linked gene

Science ◽  
2021 ◽  
Vol 371 (6527) ◽  
pp. 396-400 ◽  
Author(s):  
Charalampos Chrysovalantis Galouzis ◽  
Benjamin Prud’homme
Keyword(s):  
Gene Expression ◽  
Sexual Dimorphism ◽  
Sex Determination ◽  
Expression Pattern ◽  
X Chromosome ◽  
Expression Patterns ◽  
Gene Expression Patterns ◽  
Regulatory Interaction ◽  
Linked Gene ◽  
Homologous Chromosomes

Sexual dimorphism in animals results from sex-biased gene expression patterns. These patterns are controlled by genetic sex determination hierarchies that establish the sex of an individual. Here we show that the male-biased wing expression pattern of the Drosophila biarmipes gene yellow, located on the X chromosome, is independent of the fly sex determination hierarchy. Instead, we find that a regulatory interaction between yellow alleles on homologous chromosomes (a process known as transvection) silences the activity of a yellow enhancer functioning in the wing. Therefore, this enhancer can be active in males (XY) but not in females (XX). This transvection-dependent enhancer silencing requires the yellow intron and the chromatin architecture protein Mod(mdg4). Our results suggest that transvection can contribute more generally to the sex-biased expression of X-linked genes.

Temperature-dependent sex determination is mediated by pSTAT3 repression of Kdm6b

Science ◽  
2020 ◽  
Vol 368 (6488) ◽  
pp. 303-306 ◽  
Author(s):  
Ceri Weber ◽  
Yingjie Zhou ◽  
Jong Gwan Lee ◽  
Loren L. Looger ◽  
Guoying Qian ◽  
...  
Keyword(s):  
Causal Link ◽  
Trachemys Scripta ◽  
Temperature Sensitive ◽  
Signal Transducer ◽  
Temperature Dependent ◽  
Trachemys Scripta Elegans ◽  
Slider Turtle ◽  
Stat3 Phosphorylation ◽  
Epigenetic Regulator ◽  
Transcription 3

In many reptiles, including the red-eared slider turtle Trachemys scripta elegans (T. scripta), sex is determined by ambient temperature during embryogenesis. We previously showed that the epigenetic regulator Kdm6b is elevated at the male-producing temperature and essential to activate the male pathway. In this work, we established a causal link between temperature and transcriptional regulation of Kdm6b. We show that signal transducer and activator of transcription 3 (STAT3) is phosphorylated at the warmer, female-producing temperature, binds the Kdm6b locus, and represses Kdm6b transcription, blocking the male pathway. Influx of Ca2+, a mediator of STAT3 phosphorylation, is elevated at the female temperature and acts as a temperature-sensitive regulator of STAT3 activation.

Zfy gene expression patterns are not compatible with a primary role in mouse sex determination

Nature ◽  
1989 ◽  
Vol 342 (6252) ◽  
pp. 940-942 ◽  
Author(s):  
Peter Koopman ◽  
John Gubbay ◽  
Jérôme Collignon ◽  
Robin Lovell-Badge
Keyword(s):  
Gene Expression ◽  
Sex Determination ◽  
Expression Patterns ◽  
Gene Expression Patterns ◽  
Primary Role

Gene expression patterns in blood predict future severe endpoints in community acquired pneumonia

Pneumologie ◽  
2018 ◽  
Vol 72 (S 01) ◽  
pp. S8-S9
Author(s):  
M Bauer ◽  
H Kirsten ◽  
E Grunow ◽  
P Ahnert ◽  
M Kiehntopf ◽  
...  
Keyword(s):  
Gene Expression ◽  
Expression Patterns ◽  
Community Acquired Pneumonia ◽  
Gene Expression Patterns
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