scholarly journals In vivo placental MRI shape and textural features predict fetal growth restriction and postnatal outcome

2017 ◽  
Vol 47 (2) ◽  
pp. 449-458 ◽  
Author(s):  
Sonia Dahdouh ◽  
Nickie Andescavage ◽  
Sayali Yewale ◽  
Alexa Yarish ◽  
Diane Lanham ◽  
...  
Keyword(s):  
Fetal Growth ◽  
Fetal Growth Restriction ◽  
Growth Restriction ◽  
Textural Features ◽  
Postnatal Outcome

scholarly journals Anisotropy in the Human Placenta in Pregnancies Complicated by Fetal Growth Restriction

2021 ◽  
pp. 263-276
Author(s):  
Paddy J. Slator ◽  
Alison Ho ◽  
Spyros Bakalis ◽  
Laurence Jackson ◽  
Lucy C. Chappell ◽  
...  
Keyword(s):  
Fetal Growth ◽  
Human Placenta ◽  
Fetal Growth Restriction ◽  
Diffusion Mri ◽  
Growth Restriction ◽  
Placental Function ◽  
Unique Structure ◽  
Branching Structures ◽  
Mri Scans

AbstractThe placenta has a unique structure, which enables the transfer of oxygen and nutrients from the mother to the developing fetus. Abnormalities in placental structure are associated with major complications of pregnancy; for instance, changes in the complex branching structures of fetal villous trees are associated with fetal growth restriction. Diffusion MRI has the potential to measure such fine placental microstructural details. Here, we present in-vivo placental diffusion MRI scans from controls and pregnancies complicated by fetal growth restriction. We find that after 30 weeks’ gestation fractional anisotropy is significantly higher in placentas associated with growth restricted pregnancies. This shows the potential of diffusion MRI derived measures of anisotropy for assessing placental function during pregnancy.

scholarly journals Prenatal diagnosis of fetal growth restriction with polyhydramnios, etiology and impact on postnatal outcome

2022 ◽  
Vol 12 (1) ◽  
Author(s):  
Adeline Walter ◽  
Elina Calite ◽  
Christoph Berg ◽  
Ulrich Gembruch ◽  
Andreas Müller ◽  
...  
Keyword(s):  
Fetal Growth ◽  
Fetal Growth Restriction ◽  
Growth Restriction ◽  
Growth Delay ◽  
Chromosomal Anomalies ◽  
High Morbidity ◽  
Ultrasound Findings ◽  
Long Term Follow Up ◽  
Postnatal Outcome ◽  
Malformation Syndromes

AbstractTo assess the spectrum of different etiologies, the intrauterine course, outcome and possible prognostic markers in prenatally detected fetal growth restriction (FGR) combined with polyhydramnios. Retrospective study of 153 cases with FGR combined with Polyhydramnios diagnosed by prenatal ultrasound over a period of 17 years. Charts were reviewed for ultrasound findings, prenatal and postnatal outcome. All cases were categorized into etiological groups and examined for differences. Five etiological groups were identified: chromosomal anomalies (n = 64, 41.8%), complex malformation syndromes (n = 37, 24.1%), isolated malformations (n = 24, 15.7%), musculoskeletal disorders (n = 14, 9.2%) and prenatal non-anomalous fetuses (n = 14, 9.2%). Subgroups showed significant disparities in initial diagnosis of combination of both pathologies, Ratio AFI/ gestational weeks and Doppler ultrasound examinations. Overall mortality rate was 64.7%. Fetuses prenatally assigned to be non-anomalous, showed further complications in 42.9% (n = 6). Fetuses prenatally diagnosed with FGR combined with polyhydramnios are affected by a high morbidity and mortality. Five etiologic groups can be differentiated, showing significant disparities in prenatal and postnatal outcome. Even without recognizable patterns prenatally, long-term-follow up is necessary, as neurodevelopmental or growth delay may occur.

scholarly journals Prenatal Diagnosis of Fetal Growth Restriction With Polyhydramnios: Etiology and Impact on Postnatal Outcome

2021 ◽  
Author(s):  
Adeline Walter ◽  
Elina Calite ◽  
Christoph Berg ◽  
Ulrich Gembruch ◽  
Andreas Müller ◽  
...  
Keyword(s):  
Fetal Growth ◽  
Fetal Growth Restriction ◽  
Growth Restriction ◽  
Growth Delay ◽  
Chromosomal Anomalies ◽  
High Morbidity ◽  
Ultrasound Findings ◽  
Long Term Follow Up ◽  
Postnatal Outcome ◽  
Malformation Syndromes

Abstract Purpose: To assess the spectrum of different etiologies, the intrauterine course, outcome and possible prognostic markers in prenatally detected fetal growth restriction (FGR) combined with polyhydramnios. Methods: Retrospective study of 153 cases with FGR combined with Polyhydramnios diagnosed by prenatal ultrasound over a period of 17 years. Charts were reviewed for ultrasound findings, prenatal and postnatal outcome. All cases were categorized into etiological groups and examined for differences.Results: Five etiological groups were identified: chromosomal anomalies (n= 64, 41.8 %), complex malformation syndromes (n=37, 24.1 %), isolated malformations (n=24, 15.7 %), musculoskeletal disorders (n=14, 9.2 %) and prenatal non-anomalous fetuses (n=14, 9.2 %). Subgroups showed significant disparities in initial diagnosis of combination of both pathologies, Ratio AFI/ gestational weeks and Doppler ultrasound examinations. Overall mortality rate was 64.7 %. Fetuses prenatally assigned to be non-anomalous, showed further complications in 42.9 % (n=6). Conclusion: Fetuses prenatally diagnosed with FGR combined with polyhydramnios are affected by a high morbidity and mortality. Five etiologic groups can be differentiated, showing significant disparities in prenatal and postnatal outcome. Even without recognizable patterns prenatally, long-term-follow up is necessary, as neurodevelopmental or growth delay may occur.

FETAL GROWTH RESTRICTION WITH EARLY AND LATE MANIFESTATION, PROGNOSTIC MARKERS

2020 ◽  
pp. 27-30
Author(s):  
Yakubova D.I.
Keyword(s):  
Risk Factors ◽  
Pregnant Women ◽  
Fetal Growth ◽  
Fetal Growth Restriction ◽  
Prenatal Screening ◽  
Prognostic Markers ◽  
Growth Restriction ◽  
Late Manifestation ◽  
Late Form ◽  
Early Manifestation

Objective of the study: Comprehensive assessment of risk factors, the implementation of which leads to FGR with early and late manifestation. To evaluate the results of the first prenatal screening: PAPP-A, B-hCG, made at 11-13 weeks. Materials and Methods: A retrospective study included 110 pregnant women. There were 48 pregnant women with early manifestation of fetal growth restriction, 62 pregnant women with late manifestation among them. Results of the study: The risk factors for the formation of the FGR are established. Statistically significant differences in the indicators between groups were not established in the analyses of structures of extragenital pathology. According to I prenatal screening, there were no statistical differences in levels (PAPP-A, b-hCG) in the early and late form of FGR.

INTRAUTERINE GROWTH RETARDATION - A REVIEW ARTICLE

2018 ◽  
pp. 184-195
Author(s):  
Minh Son Pham ◽  
Vu Quoc Huy Nguyen ◽  
Dinh Vinh Tran
Keyword(s):  
Fetal Growth ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Fetal Growth Restriction ◽  
Growth Restriction ◽  
Growth Potential ◽  
National Guidelines ◽  
Intrauterine Growth ◽  
No Gold Standard

Small for gestational age (SGA) and fetal growth restriction (FGR) is difficult to define exactly. In this pregnancy condition, the fetus does not reach its biological growth potential as a consequence of impaired placental function, which may be because of a variety of factors. Fetuses with FGR are at risk for perinatal morbidity and mortality, and poor long-term health outcomes, such as impaired neurological and cognitive development, and cardiovascular and endocrine diseases in adulthood. At present no gold standard for the diagnosis of SGA/FGR exists. The first aim of this review is to: summarize areas of consensus and controversy between recently published national guidelines on small for gestational age or fetal growth restriction; highlight any recent evidence that should be incorporated into existing guidelines. Another aim to summary a number of interventions which are being developed or coming through to clinical trial in an attempt to improve fetal growth in placental insufficiency. Key words: fetal growth restriction (FGR), Small for gestational age (SGA)

The secrets of placental mosaicism: clinical observation of the full form of confined placental trisomy 22 and literature review

2020 ◽  
Author(s):  
I.V. Komarova, A.A. Nikiforenko, A.V. Fedunyak
Keyword(s):  
Prenatal Diagnosis ◽  
Literature Review ◽  
Fetal Growth ◽  
Fetal Growth Restriction ◽  
Clinical Observation ◽  
Growth Restriction ◽  
Favorable Outcome ◽  
Full Form ◽  
Placental Mosaicism ◽  
In Pregnancy

Literature reports of placental mosaicism, including trisomy 22, were analyzed. The chance of correlation of placental aneuploidy with fetus aneuploidy, also the probability of complications in pregnancy and fetal growth restriction and postnatal patients growth in the cases of confined placental mosaicism, were demonstrated. The case of prenatal diagnosis of confined placental mosaicism of trisomy 22 with favorable outcome is presented. The necessity of cytogenic assay of amniocytes and fetal lymphocytes in the case of placental heteroploidy diagnosis was emphasized.

Sign in / Sign up

Export Citation Format

Share Document