scholarly journals Immunogenicity After Two Doses of Inactivated Virus Vaccine in Healthcare Workers with and without Previous COVID‐19 Infection: Prospective Observational Study

Author(s):  
Tuğba Yanık Yalçın ◽  
Deniz İlhan Topçu ◽  
Özlem Doğan ◽  
Saliha Aydın ◽  
Nuran Sarı ◽  
...  
2013 ◽  
Vol 34 (7) ◽  
pp. 759-761 ◽  
Author(s):  
Michael Strasser ◽  
Elmar Aigner ◽  
Ilse Schmid ◽  
Andreas Stadlmayr ◽  
David Niederseer ◽  
...  

BMJ Open ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. e047716
Author(s):  
Clarissa Y M Carvalho ◽  
Jan Schumacher ◽  
Paul Robert Greig ◽  
Danny J N Wong ◽  
Kariem El-Boghdadly

ObjectiveTo describe success rates of respiratory protective equipment (RPE) fit testing and factors associated with achieving suitable fit.DesignProspective observational study of RPE fit testing according to health and safety, and occupational health requirements.SettingA large tertiary referral UK healthcare facility.Population1443 healthcare workers undergoing quantitative fit testing.Main outcome measuresQuantitative fit test success (pass/fail) and the count of tests each participant required before successful fit.ResultsHealthcare workers were fit tested a median (IQR) 2 (1–3) times before successful fit was obtained. Males were tested a median 1 (1–2) times, while females were tested a median 2 (1–2) times before a successful fit was found. This difference was statistically significant (p<0.001). Modelling each fit test as its own independent trial (n=2359) using multivariable logistic regression, male healthcare workers were significantly more likely to find a well-fitting respirator and achieve a successful fit on first attempt in comparison to females, after adjusting for other factors (adjusted OR=2.07, 95% CI): 1.66 to 2.60, p<0.001). Staff who described their ethnicity as White were also more likely to achieve a successful fit compared with staff who described their ethnicity as Asian (OR=0.47, 95% CI: 0.38 to 0.58, p<0.001), Black (OR=0.54, 95% CI: 0.41 to 0.71, p<0.001), mixed (OR=0.50 95% CI: 0.31 to 0.80, p=0.004) or other (OR=0.53, 95% CI: 0.29 to 0.99, p=0.043).ConclusionsMale and White ethnicity healthcare workers are more likely to achieve RPE fit test success. This has broad operational implications to healthcare services with a large female and Black, Asian and minority ethnic group population. Fit testing is imperative in ensuring RPE effectiveness in protecting healthcare workers during the COVID-19 pandemic and beyond.


Author(s):  
Anna Maria Cattelan ◽  
Lolita Sasset ◽  
Eugenia Di Meco ◽  
Silvia Cocchio ◽  
Francesco Barbaro ◽  
...  

Background: Since the beginning of SARS-CoV-2 outbreak, a large number of infections have been reported among healthcare workers (HCWs). The aim of this study was to investigate the occurrence of SARS-CoV-2 infection among HCWs involved in the first management of infected patients and to describe the measures adopted to prevent the transmission in the hospital. Methods: This prospective observational study was conducted between February 21 and April 16, 2020, in the Padua University Hospital (north-east Italy). The infection control policy adopted consisted of the following: the creation of the “Advanced Triage” area for the evaluation of SARS-CoV-2 cases, and the implementation of an integrated infection control surveillance system directed to all the healthcare personnel involved in the Advance Triage area. HCWs were regularly tested with nasopharyngeal swabs for SARS-CoV-2; body temperature and suggestive symptoms were evaluated at each duty. Demographic and clinical data of both patients and HCWs were collected and analyzed; HCWs’ personal protective equipment (PPE) consumption was also recorded. The efficiency of the control strategy among HCWs was evaluated identifying symptomatic infection (primary endpoint) and asymptomatic infection (secondary endpoint) with confirmed detection of SARS-CoV-2. Results: 7595 patients were evaluated in the Advanced Triage area: 5.2% resulted positive and 72.4% was symptomatic. The HCW team was composed of 60 members. A total of 361 nasopharyngeal swabs were performed on HCWs. All the swabs resulted negative and none of the HCWs reached the primary or the secondary endpoint. Conclusions: An integrated hospital infection control strategy, consisting of dedicated areas for infected patients, strict measures for PPE use and mass surveillance, is successful to prevent infection among HCWs.


2009 ◽  
Author(s):  
Ihori Kobayashi ◽  
Brian Hall ◽  
Courtney Hout ◽  
Vanessa Springston ◽  
Patrick Palmieri

2009 ◽  
Vol 36 (S 02) ◽  
Author(s):  
B Hotter ◽  
S Pittl ◽  
M Ebinger ◽  
G Oepen ◽  
K Jegzentis ◽  
...  

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