scholarly journals Nodal stage of stage III colon cancer: The impact of metastatic lymph node ratio

2009 ◽  
Vol 100 (3) ◽  
pp. 240-243 ◽  
Author(s):  
In Ja Park ◽  
Gyu-Seog Choi ◽  
Soo Han Jun

2009 ◽  
Vol 24 (11) ◽  
pp. 1297-1302 ◽  
Author(s):  
Chih-Chien Chin ◽  
Jeng-Yi Wang ◽  
Chien-Yuh Yeh ◽  
Yi-Hung Kuo ◽  
Wen-Shih Huang ◽  
...  






2017 ◽  
Vol 19 (2) ◽  
pp. 165-171 ◽  
Author(s):  
H. M. Mohan ◽  
C. Walsh ◽  
R. Kennelly ◽  
C. H. Ng ◽  
P. R. O'Connell ◽  
...  


2011 ◽  
Vol 253 (1) ◽  
pp. 82-87 ◽  
Author(s):  
Steven L Chen ◽  
Scott R. Steele ◽  
John Eberhardt ◽  
Kangmin Zhu ◽  
Anton Bilchik ◽  
...  


2013 ◽  
Vol 31 (4_suppl) ◽  
pp. 101-101
Author(s):  
Yaping Xu ◽  
Xiaojiang Sun ◽  
Yuanda Zheng

101 Background: Though postoperative radiation for esophageal cancer is offered in selected cases, there is conflicting evidence as to whether it improves overall survival (OS). We performed a retrospective investigation to analyze the prognosis impact of adjuvant radiation in a large cohort of patients. Methods: From 2002 to 2008, 545 patients underwent radical esophagectomy (R0) with or without postoperative radiation were eligible for retrospectively analysis. Patients were grouped to surgery only (n=346) and surgery plus postoperative radiation therapy (PORT) (n=199). Radiation dose was 50 Gy in 25 fractions. Kaplan-Meier and Cox regression analysis were used to compare OS. Results: The use of PORT was associated with significantly improved OS ( p =0.006). The median OS was 31 months in the group receiving PORT and 21 months in the group undergoing surgery alone. The addition of PORT improved OS at 3 years from 38.3 to 45.8% compared with surgery alone. For American Joint Committee on Cancer (AJCC) stage III esophageal cancer (T1-2N2M0, T3N1-2M0, T4N1-3M0), there was significant improvement on OS ( p < 0.001) in PORT group, for not only metastatic lymph-node ratio <0.25 ( p = 0.047), but also metastatic lymph-node ratio >0.25 ( p = 0.013). However, for stages IIB disease (T1-2N1M0) there was no significant differences. Conclusions: This large population-based analysis supports the use of PORT for pathologic lymph nodes positive stage III esophageal cancer. Our results suggest that a subset of such patients may benefit from aggressive local therapy.



2019 ◽  
Vol 10 (11) ◽  
pp. 2534-2540 ◽  
Author(s):  
Chang Jiang ◽  
Fang Wang ◽  
Guifang Guo ◽  
Jun Dong ◽  
Shousheng Liu ◽  
...  


2019 ◽  
Vol 34 (4) ◽  
pp. 667-673
Author(s):  
Han Deok Kwak ◽  
Jae Kyun Ju ◽  
Soo Young Lee ◽  
Chang Hyun Kim ◽  
Young Jin Kim ◽  
...  


2014 ◽  
Vol 22 (2) ◽  
pp. 528-534 ◽  
Author(s):  
Kiichi Sugimoto ◽  
Kazuhiro Sakamoto ◽  
Yuichi Tomiki ◽  
Michitoshi Goto ◽  
Kenjiro Kotake ◽  
...  


Oncotarget ◽  
2017 ◽  
Vol 8 (41) ◽  
pp. 70841-70846 ◽  
Author(s):  
Yinbo Chen ◽  
Cong Li ◽  
Yian Du ◽  
Qi Xu ◽  
Jieer Ying ◽  
...  


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