Lymph Node Ratio as a Quality and Prognostic Indicator in Stage III Colon Cancer

2011 ◽  
Vol 253 (1) ◽  
pp. 82-87 ◽  
Author(s):  
Steven L Chen ◽  
Scott R. Steele ◽  
John Eberhardt ◽  
Kangmin Zhu ◽  
Anton Bilchik ◽  
...  
2017 ◽  
Vol 19 (2) ◽  
pp. 165-171 ◽  
Author(s):  
H. M. Mohan ◽  
C. Walsh ◽  
R. Kennelly ◽  
C. H. Ng ◽  
P. R. O'Connell ◽  
...  

2014 ◽  
Vol 22 (2) ◽  
pp. 528-534 ◽  
Author(s):  
Kiichi Sugimoto ◽  
Kazuhiro Sakamoto ◽  
Yuichi Tomiki ◽  
Michitoshi Goto ◽  
Kenjiro Kotake ◽  
...  

2014 ◽  
Vol 99 (4) ◽  
pp. 344-353 ◽  
Author(s):  
Charles Sabbagh ◽  
François Mauvais ◽  
Cyril Cosse ◽  
Lionel Rebibo ◽  
Jean-Paul Joly ◽  
...  

Abstract Lymph node ratio (LNR) (positive lymph nodes/sampled lymph nodes) is predictive of survival in colon cancer. The aim of the present study was to validate the LNR as a prognostic factor and to determine the optimum LNR cutoff for distinguishing between “good prognosis” and “poor prognosis” colon cancer patients. From January 2003 to December 2007, patients with TNM stage III colon cancer operated on with at least of 3 years of follow-up and not lost to follow-up were included in this retrospective study. The two primary endpoints were 3-year overall survival (OS) and disease-free survival (DFS) as a function of the LNR groups and the cutoff. One hundred seventy-eight patients were included. There was no correlation between the LNR group and 3-year OS (P = 0.06) and a significant correlation between the LNR group and 3-year DFS (P = 0.03). The optimal LNR cutoff of 10% was significantly correlated with 3-year OS (P = 0.02) and DFS (P = 0.02). The LNR was not an accurate prognostic factor when fewer than 12 lymph nodes were sampled. Clarification and simplification of the LNR classification are prerequisites for use of this system in randomized control trials. An LNR of 10% appears to be the optimal cutoff.


2008 ◽  
Vol 15 (6) ◽  
pp. 1557-1558 ◽  
Author(s):  
Simon H. Telian ◽  
Anton J. Bilchik

Tumor Biology ◽  
2014 ◽  
Vol 35 (11) ◽  
pp. 11685-11690 ◽  
Author(s):  
Kewei Jiang ◽  
Yi Zhu ◽  
Yan Liu ◽  
Yingjiang Ye ◽  
Qiwei Xie ◽  
...  

2019 ◽  
Vol 10 (11) ◽  
pp. 2534-2540 ◽  
Author(s):  
Chang Jiang ◽  
Fang Wang ◽  
Guifang Guo ◽  
Jun Dong ◽  
Shousheng Liu ◽  
...  

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