A sensitive ultra‐fast liquid chromatography with tandem mass spectrometry method for simultaneous determination of ten constituents of Deng‐Zhan‐Xi‐Xin injection in rat plasma and its application to a comparative pharmacokinetic study in sham and middle cerebral artery occlusion rats

2020 ◽  
Vol 43 (22) ◽  
pp. 4162-4177
Author(s):  
Xin Guo ◽  
Shan Lin ◽  
Wei Liang ◽  
Xiuxiu Dou ◽  
Xinyu Wang ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Rat Plasma ◽  
Artery Occlusion ◽  
Tandem Mass ◽  
Spectrometry Method ◽  
Comparative Pharmacokinetic ◽  
Fast Liquid Chromatography ◽  
Cerebral Artery Occlusion ◽  
Xi Xin

Simultaneous determination of benzoylmesaconine and piperine in rat plasma after oral administration of Naru-3 by an ultra fast liquid chromatography-tandem mass spectrometry method and its application in a comparative pharmacokinetic study

2014 ◽  
Vol 6 (10) ◽  
pp. 3420-3428 ◽  
Author(s):  
Yidi Yin ◽  
Jingjing Liu ◽  
Huarong Xu ◽  
Chunxiao Lv ◽  
Yiyang Du ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Oral Administration ◽  
Rat Plasma ◽  
Tandem Mass ◽  
Spectrometry Method ◽  
Comparative Pharmacokinetic ◽  
Chromatography Tandem Mass Spectrometry ◽  
Liquid Chromatography Tandem Mass ◽  
Fast Liquid Chromatography

A rapid, sensitive and reliable UFLC-MS/MS method has been developed for the simultaneous quantitation of benzoylmesaconine and piperine in rat plasma after oral administration of Naru-3.

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