scholarly journals Predicting first fall in newly diagnosed Parkinson's disease: Insights from a fall-naïve cohort

2016 ◽  
Vol 31 (12) ◽  
pp. 1829-1836 ◽  
Author(s):  
Sue Lord ◽  
Brook Galna ◽  
Alison J. Yarnall ◽  
Shirley Coleman ◽  
David Burn ◽  
...  
2021 ◽  
pp. 1-12
Author(s):  
Julie Chandler ◽  
Radhika Nair ◽  
Kevin Biglan ◽  
Erin A. Ferries ◽  
Leanne Munsie ◽  
...  

Background: Characterizing patients with Parkinson’s disease (PD) and cognitive impairment is important toward understanding their natural history. Objective: Understand clinical, treatment, and cost characteristics of patients with PD pre- and post-cognitive impairment (memory loss/mild cognitive impairment/dementia or dementia treatment) recognition. Methods: 2,711 patients with PD newly diagnosed with cognitive impairment (index) were identified using administrative claims data. They were matched (1:1) on age and gender to patients with PD and no cognitive impairment (controls). These two cohorts were compared on patient characteristics, healthcare resource utilization, and total median costs for 3 years pre- and post-index using Chi-square tests, t-tests, and Wilcoxon rank-sum tests. Logistic regression was used to identify factors predicting cognitive impairment. Results: Comorbidity indices for patients with cognitive impairment increased during the 6-year study period, especially after the index. Enrollment in Medicare Advantage Prescription Drug plans vs. commercial (OR = 1.60), dual Medicare/Medicaid eligibility (OR = 1.36), cerebrovascular disease (OR = 1.24), and PD medication use (OR = 1.46) were associated with a new cognitive impairment diagnosis (all p <  0.05). A greater proportion of patients with cognitive impairment had hospitalizations and emergency department visits and higher median total healthcare costs than controls for each year pre- and post-index. Conclusion: In patients with PD newly diagnosed with cognitive impairment, comorbidity burden, hospitalizations, emergency department visits, and total costs peaked 1-year pre- and post-identification. These data coupled with recommendations for annual screening for cognitive impairment in PD support the early diagnosis and management of cognitive impairment in order to optimize care for patients and their caregivers.


2014 ◽  
Vol 5 (5) ◽  
pp. 357-358
Author(s):  
H. Kuusisto ◽  
P. Hujanen ◽  
T. Mattila ◽  
T. Luukkaala ◽  
T. Keränen

2021 ◽  
Author(s):  
Khalid Orayj ◽  
Tahani Almeleebia ◽  
Easwaran Vigneshwaran ◽  
Sultan Alshahrani ◽  
Sirajudeen. S. Alavudeen ◽  
...  

2012 ◽  
Vol 84 (1) ◽  
pp. 23-28 ◽  
Author(s):  
Mona K Beyer ◽  
Kolbjorn S Bronnick ◽  
Kristy S Hwang ◽  
Niels Bergsland ◽  
Ole Bjorn Tysnes ◽  
...  

2018 ◽  
Vol 99 (10) ◽  
pp. e62
Author(s):  
Miriam Rafferty ◽  
Jillian MacDonald ◽  
Laura Sloan ◽  
Alexandria Z. Byskosh ◽  
Santiago Toledo ◽  
...  

2019 ◽  
Vol 9 (10) ◽  
pp. 107 ◽  
Author(s):  
Andrew Soundy ◽  
Johnny Collett ◽  
Sophie Lawrie ◽  
Shelly Coe ◽  
Helen Roberts ◽  
...  

Aim: The dual aim of this research was to consider the impact of providing the First Steps program on the stories of people with Parkinson’s Disease (PD) and to investigate the psychosocial and emotional mechanisms which may explain this impact. Methods: A qualitative study using a subtle realist paradigm and hermeneutic phenomenological methodology was undertaken. A single semi-structured interview was used to consider the impact and experiences of people with PD who completed either the intervention (2-day peer-led behavior intervention using storytelling 6–8 weeks apart) or received telephone support calls as part of the active control group. Descriptive statistics and a narrative analysis were undertaken on the results. Results: Forty-two participants were invited to participate, forty of whom completed the interview. This included 18 from the intervention group and 22 from the active control group. The intervention group identified the value of the program as worth-while, demonstrating improved exercise behavior and coping mechanisms following the intervention. Three major stories (the affirmed, the validated and the transformed story) identified the impact of the intervention. Three internal mechanisms (perceived control, hope and action, and the individual’s mind set) alongside three social mechanisms (social comparison, social control and the first opportunity to share with peers) appeared to explain this impact. Conclusion: This study provides exciting and novel evidence of the impact of a peer-led psycho-educational intervention for people newly diagnosed with PD. Further research is needed to consider the impact of stories-based approaches on participants and consider a critical evaluation of the mechanisms which may explain changes in stories and self-reported behaviour.


2012 ◽  
Vol 18 ◽  
pp. S32
Author(s):  
J. Pagonabarraga ◽  
S. Martinez-Horta ◽  
R. Fernández-Bobadilla ◽  
C. Villa ◽  
R. Ribosa ◽  
...  

2008 ◽  
Vol 255 (5) ◽  
pp. 716-722 ◽  
Author(s):  
B. Post ◽  
J. D. Speelman ◽  
R. J. Haan ◽  

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