scholarly journals Vessel-encoded dynamic magnetic resonance angiography using arterial spin labeling

2010 ◽  
Vol 64 (3) ◽  
pp. 698-706 ◽  
Author(s):  
Thomas W. Okell ◽  
Michael A. Chappell ◽  
Mark W. Woolrich ◽  
Matthias Günther ◽  
David A. Feinberg ◽  
...  

2010 ◽  
Vol 64 (2) ◽  
pp. 430-438 ◽  
Author(s):  
Thomas W. Okell ◽  
Michael A. Chappell ◽  
Mark W. Woolrich ◽  
Matthias Günther ◽  
David A. Feinberg ◽  
...  


2017 ◽  
Author(s):  
Renzo Phellan ◽  
Thomas Lindner ◽  
Alexandre X. Falcão ◽  
Nils D. Forkert


Stroke ◽  
2016 ◽  
Vol 47 (suppl_1) ◽  
Author(s):  
Haruto Uchino ◽  
Masaki Ito ◽  
Ken Kazumata ◽  
Kiyohiro Houkin

Introduction: Recently, four-dimensional magnetic resonance angiography without contrast enhancement using arterial spin labeling (ASL-4D MRA) has become available to visualize the intracranial arteries. However, few reports are available about the efficacy of ASL-4D MRA in moyamoya disease (MMD). Hypothesis: We hypothesized that postoperative hemodynamic changes in MMD patients could be evaluated using ASL-4D MRA. Methods: This study included 26 hemispheres of 21 patients who underwent combined direct and indirect revascularization for MMD. ASL-4D MRA was serially performed before and after surgery. We assessed the time phases where signals of the arteries were detected on ASL-4D MRA in order to analyze perioperative changes in cerebral hemodynamics. Results: The signals of the anastomosed arteries on ASL-4D MRA were detected and disappeared at significantly earlier time phase after surgery than before. This change in acute period was moderated in chronic period after surgery. Postoperative hyperperfusion was observed in 12 of 26 hemispheres within 7 days after surgery. The signals of the arteries were detected significantly earlier in hemispheres with hyperperfusion than those without. In cases with hyperperfusion, ASL-4D MRA demonstrated high intensity of peripheral middle cerebral artery (MCA) around anastomosed region in early time phase (Figure). This “early hyperintensity of MCA” was observed in all cases with hyperperfusion and corresponded to the timing of the occurrence of hyperperfusion. Furthermore, this hyperperfusion-specific sign could not be detected by routine TOF MRA. Conclusions: Noninvasive ASL-4D MRA successfully evaluated perioperative dynamic changes of cerebral blood flow and the effect of surgical revascularization in MMD. This next generation modality could also visualize cerebral hemodynamics in cases with postoperative hyperperfusion and would be quite useful for appropriate postoperative management.



2018 ◽  
Vol 10 (1) ◽  
pp. 66-71 ◽  
Author(s):  
Tatsuya Ueno ◽  
Tatsuya Sasaki ◽  
Masatoshi Iwamura ◽  
Tomoya Kon ◽  
Jin-ichi Nunomura ◽  
...  

An 83-year-old Japanese man was admitted with dysarthria and right hemiparesis. He had had a large intracranial aneurysm on the left internal carotid artery 5 years before admission and had been followed up under conservative treatment. On admission, diffusion-weighted imaging revealed a hyperintense signal on the left anterior choroidal artery territory. Time-of-flight magnetic resonance angiography demonstrated poor visibility of the middle and anterior cerebral arteries and the inferior giant aneurysm, suggesting distal emboli from aneurysm thrombosis or a reduction of blood outflow due to aneurysm thrombosis. Arterial spin labeling (ASL) signal increased in the giant aneurysm, suggesting blood stagnation within the aneurysmal sac, and decreased in the left hemisphere. We diagnosed cerebral infarction due to aneurysm thrombosis, and started antithrombotic therapy. On day 2, he suddenly died of subarachnoid hemorrhage due to rupturing of the giant aneurysm. When thrombosis occurs in a giant aneurysm, increasing ASL signal within the aneurysm and decreasing ASL signal with poor visibility on magnetic resonance angiography in the same arterial territory may indicate the danger of impending rupture of the giant aneurysm.





2019 ◽  
Vol 32 (3) ◽  
pp. 173-178
Author(s):  
Tsuyoshi Oshita ◽  
Hidetake Yabuuchi ◽  
Masanobu Osame

Purpose To optimize the post-label delay in single-phase arterial spin labeling (SP-ASL) using multi-phase ASL in 4-dimensional magnetic resonance angiography (4D-MRA). Methods Ten healthy volunteers (six men, four women; age range, 24–37 years; mean, 29.1) were enrolled. 4D-MRA and SP-ASL were performed on a 3T magnetic resonance imaging (MRI) scanner. Signal intensities in four cerebral arterial territories (anterior cerebral artery, middle cerebral artery, posterior cerebral artery, and whole area) were measured using both 4D-MRA and SP-ASL, and peak time of maximum intensity through each technique was recorded. Regression analysis was used to determine the correlation between the peak times using 4D-MRA and those using SP-ASL, and the regression function obtained was used to estimate the peak time for SP-ASL (optimum post-label delay) from that obtained for 4D-MRA. Results The peak time in anterior cerebral artery territory for SP-ASL was expressed as 1.19 + 0.30 × (peak time of 4D-MRA) s, ( p = 0.017, r2 = 0.14). The peak time in middle cerebral artery territory for SP-ASL was 0.96 + 0.58 × (peak time of 4D-MRA) s, ( p < 0.001, r2 = 0.32). The peak time in posterior cerebral artery territory for SP-ASL was expressed as 0.92 + 0.58 × (peak time of 4D-MRA) s, ( p < 0.001, r2 = 0.33). The peak time in whole brain for SP-ASL was expressed as 1.04 + 0.46 × (peak time of 4D-MRA) s, ( p < 0.001, r2 = 0.25). Conclusion The peak time values at 4D-MRA showed potential for use in predicting the optimum post-label delay of SP-ASL.



Sign in / Sign up

Export Citation Format

Share Document