Evaporative light scattering and thermospray mass spectrometry: Two alternative methods for detection and quantitative liquid chromatographic determination of ginkgolides and bilobalide inGinkgo biloba leaf extracts and phytopharmaceuticals

1995 ◽  
Vol 6 (3) ◽  
pp. 141-148 ◽  
Author(s):  
Fabrizio F. Camponovo ◽  
Jean-Luc Wolfender ◽  
Marc P. Maillard ◽  
Olivier Potterat ◽  
Kurt Hostettmann
Keyword(s):  
Mass Spectrometry ◽  
Light Scattering ◽  
Chromatographic Determination ◽  
Alternative Methods ◽  
Leaf Extracts ◽  
Evaporative Light Scattering ◽  
Liquid Chromatographic Determination ◽  
Liquid Chromatographic ◽  
Thermospray Mass Spectrometry

Liquid Chromatographic Determination of Moxidectin Residues in Cattle Tissues and Confirmation in Cattle Fat by Liquid Chromatography/Mass Spectrometry

1993 ◽  
Vol 76 (6) ◽  
pp. 1230-1235 ◽  
Author(s):  
Alisa Khunachak ◽  
Adrian R Dacunha ◽  
Steven J Stout
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Limit Of Detection ◽  
Parent Compound ◽  
Chromatographic Determination ◽  
Liquid Chromatography Mass Spectrometry ◽  
Liver And Kidney ◽  
Liquid Chromatographic Determination ◽  
Liquid Chromatographic

Abstract Moxidectin, a potent new endo- and ectoparasitic agent, is determined in cattle tissues by liquid chromatography (LC) with fluorescence detection. Moxidectin residues in cattle fat are confirmed with thermospray LC/mass spectrometry (MS). Moxidectin is extracted from the tissue with acetonitrile; the extract is partitioned with hexane, concentrated, and reacted with acetic anhydride, 1-methylimidazole, and dimethylformamide to produce a fluorescent product. The validated sensitivity of the LC/fluorescence method was 10 ppb, with a limit of detection typically between 1 and 2 ppb. Average recoveries from cattle fat, muscle, liver, and kidney were 99,95,89, and 92%, respectively. LC/MS confirmatory method determined the underivatized parent compound following the acetonitrilehexane partitioning step, with an average recovery of 108% at the 250 ppb level in cattle fat.

Gas-Liquid Chromatographic Determination of Kepone in Field-Collected Avian Tissues and Eggs

1978 ◽  
Vol 61 (1) ◽  
pp. 08-14 ◽  
Author(s):  
Charles J Stafford ◽  
William L Reichel ◽  
Douglas M Swineford ◽  
Richard M Prouty ◽  
Martha L Gay
Keyword(s):  
Mass Spectrometry ◽  
Chromatographic Determination ◽  
Bald Eagle ◽  
Gas Liquid Chromatography ◽  
Tissue Samples ◽  
Florisil Column ◽  
Average Recovery ◽  
Liquid Chromatographic Determination ◽  
Liquid Chromatographic

Abstract A procedure is described for determining Kepone (decachlorooctahydro-l,3,4-metheno-2H-cyclobuta [cd]pentalene-2-one) residues in avian egg, liver, and tissue. Samples were extracted with benzene-isopropanol, and the extract was cleaned up with fuming H2SO4-concentrated H2SO4. Kepone was separated from organochlorine pesticides and polychlorinated biphenyls on a Florisil column and analyzed by electron capture gas-liquid chromatography GLC). The average recovery from spiked tissues was 86%. The analyses performed on 14 bald eagle carcasses and livers, 3 bald eagle eggs, and 14 osprey eggs show measurable levels which indicate that Kepone accumulates in the tissues of fish-eating birds. Residues were confirmed by GLC-mass spectrometry.

Gas-Liquid Chromatographic Determination of Ethylenediaminetetraacetic Acid in Pickled Vegetables

1974 ◽  
Vol 57 (6) ◽  
pp. 1383-1385
Author(s):  
David T Williams
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Ethylenediaminetetraacetic Acid ◽  
Chromatographic Determination ◽  
Gas Liquid Chromatography ◽  
Liquid Chromatography Mass Spectrometry ◽  
Liquid Chromatographic Determination ◽  
Liquid Chromatographic ◽  
Pickled Vegetables

Abstract A method has been developed for the determination of ethylenediaminetetraacetic acid in pickled vegetables after conversion to its tetramethyl ester. The ester is identified by gas-liquid chromatography and confirmed by gas-liquid chromatography-mass spectrometry. Recoveries from pickled beet samples spiked at 20-250 ppm were 87-74%.

Sign in / Sign up

Export Citation Format

Share Document