Prediction of adverse pregnancy outcomes by combinations of first and second trimester biochemistry markers used in the routine prenatal screening of Down syndrome

2010 ◽  
pp. n/a-n/a ◽  
Author(s):  
Tianhua Huang ◽  
Barry Hoffman ◽  
Wendy Meschino ◽  
John Kingdom ◽  
Nanette Okun
Keyword(s):  
Down Syndrome ◽  
Pregnancy Outcomes ◽  
Prenatal Screening ◽  
Adverse Pregnancy Outcomes ◽  
Second Trimester ◽  
Adverse Pregnancy

scholarly journals Association of maternal hepatitis B virus infection with adverse pregnancy outcomes and prenatal screening result of second-trimester: a retrospective cohort study

2020 ◽  
Author(s):  
Quanze He ◽  
You Zhou ◽  
Xiaojuan Wu ◽  
Ying Xue ◽  
Chunhua Zhang ◽  
...  
Keyword(s):  
Cohort Study ◽  
Pregnancy Outcomes ◽  
Retrospective Cohort ◽  
Prenatal Screening ◽  
Adverse Pregnancy Outcomes ◽  
Hbv Infection ◽  
Second Trimester ◽  
Extrauterine Pregnancy ◽  
Biochemical Pregnancy ◽  
Adverse Pregnancy

AbstractObjectiveThe association between maternal HBV infection and adverse pregnancy outcomes remains controversial and the prenatal screening features was not investigated though they strongly indicate adverse pregnancy outcomes. We conducted a retrospective cohort study to determine the association between maternal HBV infection and adverse pregnancy outcomes and the result of prenatal screening.DesignThe information from 65,257 pregnant women who performed non-invasive prenatal screening (NIPS) in second-trimester from July 2015 to Nov 2019 in Suzhou, China were collected. The participants were divided into the group of “control” (n = 63,591) and “exposure” (n = 1,666). Meanwhile, eight types of adverse pregnancy outcomes in history and twelve prenatal screening results in the second-trimester of current pregnancy were investigated by estimating and adjusting their risk ratios (aRR) for women between HBV infected and uninfected using multivariate logic regression.ResultOur results suggested that women infected with HBV have higher risks on the biochemical pregnancy, extrauterine pregnancy and three kinds of screen result for fetal Down’s syndrome (DS) than women with HBV un-infected. Meanwhile, the diagnostic result for the positive result of fetal Down syndrome in NIPS suggested the 98% additional risk in women with HBV infected than uninfected and supported by all adjusted models.ConclusionTaken together, maternal HBV infection is an independent risk factor of biochemical pregnancy, extrauterine pregnancy, and fetal Down’s syndrome. It also indicates the influence of maternal HBV infection way across all gestation.

Comparison of pregnancy outcomes after second trimester amniocentesis between procedures performed by experts and non-experts

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Tanapak Wisetmongkolchai ◽  
Fuanglada Tongprasert ◽  
Kasemsri Srisupundit ◽  
Suchaya Luewan ◽  
Kuntharee Traisrisilp ◽  
...  
Keyword(s):  
Pregnancy Outcomes ◽  
Loss Rate ◽  
Fetal Loss ◽  
Adverse Pregnancy Outcomes ◽  
Expert Group ◽  
Second Trimester ◽  
Single Institution ◽  
Adverse Pregnancy ◽  
In Pregnancy ◽  
Singleton Pregnancies

AbstractObjectivesTo compare the rate of fetal loss in pregnancy after second trimester amniocentesis between procedures performed by experts and non-experts and to assess other pregnancy complications as secondary outcomes.MethodsA retrospective cohort study was performed on singleton pregnancies that underwent mid-trimester amniocenteses in a single institution. The fetal loss rates of procedures performed by experts and non-experts were collected and analyzed. Other adverse pregnancy outcomes were also examined.ResultsIn total, 14,450 amniocenteses were performed during the study period. These included 11,357 (78.6%) procedures in the group expert operators and 3,093 (21.4%) procedures in the group non-expert operators. In the non-expert group, the fetal loss rate was slightly increased but not significantly (p=0.24).In addition, the higher number of spontaneous abortions was associated with blood-stained amniotic fluid sample (p<0.001; RR=9.28). Multiple needle insertions also increased in the non-expert group significantly. However, no difference in pregnancy outcomes was found between in single and multiple needle insertions.ConclusionsThe amniocentesis procedures performed by the non-experts was not increase the fetal loss rate. However, the other adverse pregnancy outcomes, including preterm birth, low birth weight and fetal growth restriction were significantly increased in the non-expert group.

Second trimester biparietal diameter size and the risk of adverse pregnancy outcomes

2011 ◽  
Vol 31 (10) ◽  
pp. 995-998 ◽  
Author(s):  
Vajiheh Marsoosi ◽  
Reihaneh Pirjani ◽  
Ashraf Jamal ◽  
Laleh Eslamian ◽  
Abbas Rahimi-Foroushani
Keyword(s):  
Pregnancy Outcomes ◽  
Adverse Pregnancy Outcomes ◽  
Second Trimester ◽  
Biparietal Diameter ◽  
Adverse Pregnancy

Association between isolated abnormal levels of maternal serum unconjugated estriol in the second trimester and adverse pregnancy outcomes

2015 ◽  
Vol 29 (13) ◽  
pp. 2093-2097 ◽  
Author(s):  
Thaniyaporn Settiyanan ◽  
Chanane Wanapirak ◽  
Supatra Sirichotiyakul ◽  
Fuanglada Tongprasert ◽  
Kasemsri Srisupundit ◽  
...  
Keyword(s):  
Pregnancy Outcomes ◽  
Maternal Serum ◽  
Adverse Pregnancy Outcomes ◽  
Second Trimester ◽  
Adverse Pregnancy ◽  
Unconjugated Estriol

No. 348-Joint SOGC-CCMG Guideline: Update on Prenatal Screening for Fetal Aneuploidy, Fetal Anomalies, and Adverse Pregnancy Outcomes

2017 ◽  
Vol 39 (9) ◽  
pp. 805-817 ◽  
Author(s):  
Francois Audibert ◽  
Isabelle De Bie ◽  
Jo-Ann Johnson ◽  
Nanette Okun ◽  
R. Douglas Wilson ◽  
...  
Keyword(s):  
Pregnancy Outcomes ◽  
Prenatal Screening ◽  
Adverse Pregnancy Outcomes ◽  
Fetal Anomalies ◽  
Fetal Aneuploidy ◽  
Adverse Pregnancy

scholarly journals Abnormal First And Second Trimester Matenal Seum Marker Levels For Aneuploidy Screening And Adverse Pregnancy Outcomes

2021 ◽  
Vol 26 (3) ◽  
pp. 418-425
Author(s):  
Lale Susan Turkgeldi ◽  
Engin Turkgeldi ◽  
Huseyin Kiyak ◽  
NEŞE YÜCEL
Keyword(s):  
Pregnancy Outcomes ◽  
Adverse Pregnancy Outcomes ◽  
Second Trimester ◽  
Aneuploidy Screening ◽  
Adverse Pregnancy

scholarly journals First trimester prenatal screening in multiple pregnancies. Part II: serum proteins PAPP-A and β-hCG as markers of adverse pregnancy outcomes

2020 ◽  
Vol 14 (1) ◽  
pp. 34-43 ◽  
Author(s):  
V. I. Tsibizova ◽  
I. E. Govorov ◽  
T. M. Pervunina ◽  
E. V. Komlichenko ◽  
E. K. Kudryashova ◽  
...  
Keyword(s):  
Pregnancy Outcomes ◽  
Prenatal Screening ◽  
Serum Proteins ◽  
First Trimester ◽  
Adverse Pregnancy Outcomes ◽  
Multiple Pregnancies ◽  
Adverse Pregnancy ◽  
Β Hcg

Serum screening for Down syndrome and adverse pregnancy outcomes: a case-controlled study

2000 ◽  
Vol 20 (2) ◽  
pp. 96-99 ◽  
Author(s):  
Robert Ogle ◽  
Eric Jauniaux ◽  
Gurmit S. Pahal ◽  
Elissa Dell ◽  
Ann Sheldrake ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Pregnancy Outcomes ◽  
Adverse Pregnancy Outcomes ◽  
Controlled Study ◽  
Serum Screening ◽  
Adverse Pregnancy

Combination of lipids and uric acid in mid-second trimester can be used to predict adverse pregnancy outcomes

2012 ◽  
Vol 25 (12) ◽  
pp. 2633-2638 ◽  
Author(s):  
Jianjun Zhou ◽  
Xia Zhao ◽  
Zhiqun Wang ◽  
Yali Hu
Keyword(s):  
Uric Acid ◽  
Pregnancy Outcomes ◽  
Adverse Pregnancy Outcomes ◽  
Second Trimester ◽  
Adverse Pregnancy
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