Carruthers, W.: Some modern methods of organic synthesis. Hrsg.: General Editors: Benkovic, S. J.; Elmore, D. T.; Lewis, J.; Schofield, K.; Thomas, J. M.; Thrush, B. A., 3. Aufl. 526 S., 12 Tab., Format 15,2 × 22,8 cm Cambridge: Cambridge University Press

1988 ◽  
Vol 330 (1) ◽  
pp. 160-160
Author(s):  
E. Fanghänel
1971 ◽  
Vol 17 ◽  
pp. 303-326 ◽  

Edward Armand Guggenheim was born on 11 August 1901 in Manchester; he was the elder brother of a family of three. His father, Armand Guggenheim, was of Swiss nationality but became a naturalized British subject at the age of forty-six in 1906. He was the senior partner in E. Spinner & Co., importers of Indian cotton and exporters of cotton cloth, especially khaki, and during the years 1917-1923 was also the Swiss Consul in Manchester. Edward after attending Terra Nova School, Birkdale, Southport, proceeded at the age of fourteen with a Junior Scholarship to Charterhouse. At first he was on the classical side but he switched to the science side where he came under the influence of two outstanding mathematics teachers, C. O. Tuckey and Alfred Lodge who was the brother of the more famous Oliver Lodge. His high intellectual qualities developed rapidly at Charterhouse, where he gained a Senior Scholarship in 1917 and was top of the sixth form in mathematical sciences for the period 1918-1920. His strong character and desire for authority were recognized by his election to the Head of House during his last year at School. Edward’s father died at the early age of 63, but his mother lived much longer and was an admirable hostess to Edward’s friends. After declining an Exhibition in the previous year, Edward won a Scholarship from Charterhouse to Cambridge University at Gonville and Caius College in 1920. One year later he obtained a first-class mathematical tripos in Part 1 and in 1923 a first-class in the natural science tripos, Part 2, in chemistry. One imagines that his theoretical papers were outstanding, since his practical ability at that time appears not to have been exceptionally high, particularly in preparative organic chemistry. After completion of an organic synthesis, which should have given a crystalline product, he was holding a test-tube containing a small volume of a viscous tarry material. It is reported that he contrived to collide with a perambulating demonstrator and, with studied carelessness, allowed the only record of his work to slip through his fingers with consequent breakage of the test-tube.


During a short stay at Plymouth, in 1889, I was engaged in studying certain points in the anatomy of Cirripedia; finding, however, that a knowledge of the embryology was necessary in order to arrive at a complete understanding of the adult structure, I became wishful to investigate the life-history of some one member of the group. This I had an opportunity of doing at Naples, where I was appointed to occupy the Cambridge University Table at the Zoological Station for a period of six months, subsequently increased to nine. I here succeeded in obtaining a practically complete series of stages of Balanus perforatus , Bruguiere, as well as many stages in other members of the group. Though a number of able observers have occupied themselves with the embryology of Cirripedes, yet, owing to lack of opportunity, and to the difficulty of obtaining complete series of developmental stages, as well' as to the inherent difficulties in the subject, much remained to be done in this line. Willemoes-Suhm alone, with the advantages afforded by his position during the Challenger Expedition, has hitherto obtained a complete series of stages of any one form, but he failed to trace the history of the earlier stages, and in the later, limited himself to the appearance of fresh and spirit specimens, as seen without cutting sections. In fact the method of sections has been little applied to the development of Cirripedes, and not at all to the earlier stages. There is, therefore, little apology needed for an account embracing the results obtained by the employment of some of the more modern methods of embryological study.


2020 ◽  
Vol 17 (3) ◽  
pp. 297-308
Author(s):  
Nidhi Singh ◽  
Jaya Pandey

: Henry reaction is an important reaction employing carbonyls which furnishes β-nitro alcohol, nitroalkene, α-nitro ketones, β-amino alcohol as products and byproducts that may be transfigured as building blocks for other synthetic reactions. This paper focuses on various synthetic routes for Henry reaction, a versatile reaction of high significance in organic synthesis. The paper discusses the chemistry and plausible products of the reaction, along with the various available synthetic routes for the same, ranging from classical conventional methods to modern methods of green chemistry trends. Use of various catalysts as rate enhancer as well as use of various catalysts as enantioselective frontman for stereoselective reactions, have been described in this work.


Synthesis ◽  
2006 ◽  
Vol 2006 (24) ◽  
pp. 4269-4269
Author(s):  
Thomas Lazar

2016 ◽  
Vol 45 (8) ◽  
pp. 2212-2238 ◽  
Author(s):  
Barry M. Trost ◽  
James T. Masters

Methods for the selective coupling of alkynes to 1,3-enynes are discussed, as are applications of these processes in organic synthesis.


RSC Advances ◽  
2021 ◽  
Vol 11 (45) ◽  
pp. 28223-28270
Author(s):  
Emmanuel Cigan ◽  
Bettina Eggbauer ◽  
Joerg H. Schrittwieser ◽  
Wolfgang Kroutil

This review article discusses developments in the chemo-enzymatic synthesis of alkaloids since 2013, showcasing how modern methods of organic synthesis and biocatalysis are combined to establish novel routes towards these important natural products.


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