The availability and usage frequency of real time ultrasound by physiotherapists in South Australia: an observational study

2008 ◽  
Vol 13 (4) ◽  
pp. 231-240 ◽  
Author(s):  
A. Jedrzejczak ◽  
L.S. Chipchase
Keyword(s):  
Observational Study ◽  
Real Time ◽  
South Australia ◽  
Usage Frequency

scholarly journals Persistence of SARS-CoV-2 Viral RNA in Nasopharyngeal Swabs after Death: An Observational Study

2021 ◽  
Vol 9 (4) ◽  
pp. 800
Author(s):  
Francesca Servadei ◽  
Silvestro Mauriello ◽  
Manuel Scimeca ◽  
Bartolo Caggiano ◽  
Marco Ciotti ◽  
...  
Keyword(s):  
Viral Load ◽  
Observational Study ◽  
Real Time ◽  
Real Time Pcr ◽  
Pcr Detection ◽  
Viral Rna ◽  
Clinical Documentation ◽  
Post Mortem ◽  
Medical Assistance ◽  
Time Points

The aim of this study was to investigate the persistence of SARS-CoV-2 in post-mortem swabs of subjects who died from SARS-CoV-2 infection. The presence of the virus was evaluated post-mortem from airways of 27 SARS-CoV-2 positive patients at three different time points (T1 2 h; T2 12 h; T3 24 h) by real-time PCR. Detection of antibodies to SARS-CoV-2 was performed by Maglumi 2019-nCoV IgM/IgG chemiluminescence assay. SARS-CoV-2 viral RNA was still detectable in 70.3% of cases within 2 h after death and in 66,6% of cases up to 24 h after death. Our data showed an increase of the viral load in 78,6% of positive individuals 24 h post-mortem (T3) in comparison to that evaluated 2 h after death (T1). Noteworthy, we detected a positive T3 post-mortem swab (24 h after death) from 4 subjects who were negative at T1 (2 h after death). The results of our study may have an important value in the management of deceased subjects not only with a suspected or confirmed diagnosis of SARS-CoV-2, but also for unspecified causes and in the absence of clinical documentation or medical assistance.

scholarly journals Influence of Illness Duration on the Sensitivity and Specificity of Influenza Antigen Testing： A Prospective Observational Study Using Real-time PCR

2021 ◽  
Vol 95 (1) ◽  
pp. 9-16
Author(s):  
Yusaku AKASH ◽  
Hiromichi SUZUKI ◽  
Yuto TAKEUCH ◽  
Atsuo UEDA ◽  
Yumi HIROSE ◽  
...  
Keyword(s):  
Observational Study ◽  
Real Time ◽  
Sensitivity And Specificity ◽  
Real Time Pcr ◽  
Prospective Observational Study ◽  
Illness Duration ◽  
Antigen Testing

Active cytomegalovirus infection diagnosed by real-time PCR in patients with inflammatory bowel disease: a prospective, controlled observational study

2016 ◽  
Vol 51 (9) ◽  
pp. 1075-1080 ◽  
Author(s):  
Mari Thörn ◽  
Fredrik Rorsman ◽  
Anders Rönnblom ◽  
Per Sangfelt ◽  
Alkwin Wanders ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Observational Study ◽  
Real Time ◽  
Bowel Disease ◽  
Real Time Pcr ◽  
Cytomegalovirus Infection ◽  
Inflammatory Bowel

Real-time continuous glucose monitoring as a tool to prevent severe hypoglycaemia in selected pregnant women with Type 1 diabetes - an observational study

2014 ◽  
Vol 31 (3) ◽  
pp. 352-356 ◽  
Author(s):  
A. L. Secher ◽  
E. Stage ◽  
L. Ringholm ◽  
C. Barfred ◽  
P. Damm ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Observational Study ◽  
Pregnant Women ◽  
Real Time ◽  
Continuous Glucose Monitoring ◽  
Severe Hypoglycaemia ◽  
Glucose Monitoring

scholarly journals An Ambulatory Blood Pressure Monitor Mobile Health System for Early Warning for Stroke Risk: Longitudinal Observational Study (Preprint)

2019 ◽  
Author(s):  
Guangyu Wang ◽  
Silu Zhou ◽  
Shahbaz Rezaei ◽  
Xin Liu ◽  
Anpeng Huang
Keyword(s):  
Blood Pressure ◽  
Observational Study ◽  
Real Time ◽  
Early Warning ◽  
Stroke Risk ◽  
Risk Level ◽  
Blood Pressure Monitor ◽  
Pressure Monitor ◽  
Blood Pressure Data ◽  
Longitudinal Observational Studies

BACKGROUND Stroke, as a leading cause of death around the globe, has become a heavy burden on our society. Studies show that stroke can be predicted and prevented if a person’s blood pressure (BP) status is appropriately monitored via an ambulatory blood pressure monitor (ABPM) system. However, currently there exists no efficient and user-friendly ABPM system to provide early warning for stroke risk in real-time. Moreover, most existing ABPM devices measure BP during the deflation of the cuff, which fails to reflect blood pressure accurately. OBJECTIVE In this study, we sought to develop a new ABPM mobile health (mHealth) system that was capable of monitoring blood pressure during inflation and could detect early stroke-risk signals in real-time. METHODS We designed an ABPM mHealth system that is based on mobile network infrastructure and mobile apps. The proposed system contains two major parts: a new ABPM device in which an inflation-type BP measurement algorithm is embedded, and an abnormal blood pressure data analysis algorithm for stroke-risk prediction services at our health data service center. For evaluation, the ABPM device was first tested using simulated signals and compared with the gold standard of a mercury sphygmomanometer. Then, the performance of our proposed mHealth system was evaluated in an observational study. RESULTS The results are presented in two main parts: the device test and the longitudinal observational studies of the presented system. The average measurement error of the new ABPM device with the inflation-type algorithm was less than 0.55 mmHg compared to a reference device using simulated signals. Moreover, the results of correlation coefficients and agreement analyses show that there is a strong linear correlation between our device and the standard mercury sphygmomanometer. In the case of the system observational study, we collected a data set with 88 features, including real-time data, user information, and user records. Our abnormal blood pressure data analysis algorithm achieved the best performance, with an area under the curve of 0.904 for the low risk level, 0.756 for the caution risk level, and 0.912 for the high-risk level. Our system enables a patient to be aware of their risk in real-time, which improves medication adherence with risk self-management. CONCLUSIONS To our knowledge, this device is the first ABPM device that measures blood pressure during the inflation process and has obtained a government medical license. Device tests and longitudinal observational studies were conducted in Peking University hospitals, and they showed the device’s high accuracy for BP measurements, its efficiency in detecting early signs of stroke, and its efficiency at providing an early warning for stroke risk.

scholarly journals An Ambulatory Blood Pressure Monitor Mobile Health System for Early Warning for Stroke Risk: Longitudinal Observational Study

10.2196/14926 ◽  
2019 ◽  
Vol 7 (10) ◽  
pp. e14926 ◽  
Author(s):  
Guangyu Wang ◽  
Silu Zhou ◽  
Shahbaz Rezaei ◽  
Xin Liu ◽  
Anpeng Huang
Keyword(s):  
Blood Pressure ◽  
Observational Study ◽  
Real Time ◽  
Early Warning ◽  
Stroke Risk ◽  
Risk Level ◽  
Blood Pressure Monitor ◽  
Pressure Monitor ◽  
Blood Pressure Data ◽  
Longitudinal Observational Studies

Background Stroke, as a leading cause of death around the globe, has become a heavy burden on our society. Studies show that stroke can be predicted and prevented if a person’s blood pressure (BP) status is appropriately monitored via an ambulatory blood pressure monitor (ABPM) system. However, currently there exists no efficient and user-friendly ABPM system to provide early warning for stroke risk in real-time. Moreover, most existing ABPM devices measure BP during the deflation of the cuff, which fails to reflect blood pressure accurately. Objective In this study, we sought to develop a new ABPM mobile health (mHealth) system that was capable of monitoring blood pressure during inflation and could detect early stroke-risk signals in real-time. Methods We designed an ABPM mHealth system that is based on mobile network infrastructure and mobile apps. The proposed system contains two major parts: a new ABPM device in which an inflation-type BP measurement algorithm is embedded, and an abnormal blood pressure data analysis algorithm for stroke-risk prediction services at our health data service center. For evaluation, the ABPM device was first tested using simulated signals and compared with the gold standard of a mercury sphygmomanometer. Then, the performance of our proposed mHealth system was evaluated in an observational study. Results The results are presented in two main parts: the device test and the longitudinal observational studies of the presented system. The average measurement error of the new ABPM device with the inflation-type algorithm was less than 0.55 mmHg compared to a reference device using simulated signals. Moreover, the results of correlation coefficients and agreement analyses show that there is a strong linear correlation between our device and the standard mercury sphygmomanometer. In the case of the system observational study, we collected a data set with 88 features, including real-time data, user information, and user records. Our abnormal blood pressure data analysis algorithm achieved the best performance, with an area under the curve of 0.904 for the low risk level, 0.756 for the caution risk level, and 0.912 for the high-risk level. Our system enables a patient to be aware of their risk in real-time, which improves medication adherence with risk self-management. Conclusions To our knowledge, this device is the first ABPM device that measures blood pressure during the inflation process and has obtained a government medical license. Device tests and longitudinal observational studies were conducted in Peking University hospitals, and they showed the device’s high accuracy for BP measurements, its efficiency in detecting early signs of stroke, and its efficiency at providing an early warning for stroke risk.

scholarly journals The COVID-19 Critical Care Consortium observational study: Design and rationale of a prospective, international, multicenter, observational study

2020 ◽  
Author(s):  
Gianluigi Li Bassi ◽  
Jacky Y. Suen ◽  
Adrian G. Barnett ◽  
Amanda Corley ◽  
Jonathan E. Millar ◽  
...  
Keyword(s):  
Critical Care ◽  
Observational Study ◽  
Real Time ◽  
Critically Ill ◽  
Large Scale ◽  
Demographic Data ◽  
Hospital Death ◽  
Case Report Form ◽  
Icu Admission ◽  
International Multicenter

ABSTRACTImportanceThere is a paucity of data that can be used to guide the management of critically ill patients with coronavirus disease 2019 (COVID-19). Global collaboration offers the best chance of obtaining these data, at scale and in time. In the absence of effective therapies, insights derived from real-time observational data will be a crucial means of improving outcomes.ObjectiveIn response to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, a research and data-sharing collaborative has been assembled to harness the cumulative experience of intensive care units (ICUs) worldwide. The resulting observational study provides a platform to rapidly disseminate detailed data and insights.DesignThe COVID-19 Critical Care Consortium observational study is an international, multicenter, prospective, observational study of patients with confirmed or suspected SARSCoV-2 infection admitted to ICUs.SettingThis is an evolving, open-ended study that commenced on January 1st, 2020 and currently includes more than 350 sites in over 48 countries. The study enrolls patients at the time of ICU admission and follows them to the time of death, hospital discharge, or 28 days post-ICU admission, whichever occurs last.ParticipantsAll subjects, without age limit, requiring admission to an ICU for SARS-CoV-2 infection, confirmed by real-time polymerase chain reaction (PCR) and/or next-generation sequencing or with high clinical suspicion of the infection. Patients admitted to an ICU for any other reason are excluded.Main outcomes and measuresKey data, collected via an electronic case report form devised in collaboration with the ISARIC/SPRINT-SARI networks, include: patient demographic data and risk factors, clinical features, severity of illness and respiratory failure, need for non-invasive and/or mechanical ventilation and/or extracorporeal membrane COVID–19 CCC observational study protocol oxygenation (ECMO), and associated complications, as well as data on adjunctive therapies. Final outcomes of in-hospital death, discharge or continuing admissions at 28 days.DiscussionThis large-scale, observational study of COVID-19 in the critically ill will provide rapid international characterization. Open-ended accrual will increase the power to answer hypothesis-led questions over time. Several sub-studies have already been initiated, examining hemostasis, neurological, cardiac, and long-term outcomes.

Determination of range enrichment for improved hen welfare on commercial fixed-range free-range layer farms

2019 ◽  
Vol 59 (7) ◽  
pp. 1336 ◽  
Author(s):  
Carolyn de Koning ◽  
Soressa M. Kitessa ◽  
Reza Barekatain ◽  
Kelly Drake
Keyword(s):  
Observational Study ◽  
South Australia ◽  
Weather Conditions ◽  
Control Treatment ◽  
Control Range ◽  
Free Range ◽  
Video Recordings ◽  
Tree Coverage ◽  
Range Free

An observational study on range enrichment was conducted on three commercial fixed-range, free-range layer farms comprising four flocks in South Australia (flock sizes ranged from 3000 to 11700 hens). Two strategies were compared; a ‘standard’ Control treatment, typical of the type of range used in the commercial industry and a highly ‘enriched’ treatment. Both treatments were implemented on the same range with no subdivisional fences. The highly enriched side of the range incorporated shade shelters, alongside a continuum of additional enrichment structures (e.g. dust baths, peck objects and hay bales). Range treatments were investigated to determine the effects on motivating hens to use the range more effectively, and their potential to lead to a decrease in abnormal behaviours, such as injurious feather pecking and cannibalism. Additionally, two farms with high levels of tree coverage were also observed. Farms were visited monthly for 6 months. At each visit several measures were recorded live: the numbers of hens out on the range, location of hens on the range and plumage score of birds outdoors and indoors. Enrichment structure utilisation on the range was measured via video recordings and continuous counts of the number of hen visits to enrichment structures within 1 h. It was found that more hens used the ‘enriched’ side of the range, in comparison with the ‘standard’ Control range treatment (P ≤ 0.01). Overhead cover provided by constructed shelters and dust bathing pits were instrumental in enticing birds out onto the range (306 ± 27 s.e.m. and 366 ± 24 s.e.m., average number hen visits). Hay bales were also highly utilised (116 ± 14 s.e.m., average number hen visits), even though the hen numbers attracted to the hay bales were not as high as shelters and dust baths. It was also observed on one property that natural cover provided by trees attracted the greatest number of hens (1652 ± 358 s.e.m., average number of hen visits). Prevailing weather conditions and the age of the flock strongly influenced the number of hens utilising the range outdoors. Furthermore, hens outside on the range had better plumage scores with lower feather loss and decreased areas of bare skin compared with birds scored in the shed.

Reduction in Hemoglobin A1c with Real-Time Continuous Glucose Monitoring: Results from a 12-Week Observational Study

2007 ◽  
Vol 9 (3) ◽  
pp. 203-210 ◽  
Author(s):  
Timothy S. Bailey ◽  
Howard C. Zisser ◽  
Satish K. Garg
Keyword(s):  
Observational Study ◽  
Real Time ◽  
Continuous Glucose Monitoring ◽  
Hemoglobin A1c ◽  
Glucose Monitoring
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