scholarly journals Species differences in sinusoidal and canalicular efflux transport of mycophenolic acid 7‐ O‐ glucuronide in sandwich‐cultured hepatocytes

2014 ◽  
Vol 2 (2) ◽  
Author(s):  
Kazuhiro Tetsuka ◽  
Nicolas Gerst ◽  
Kouichi Tamura ◽  
Jeffrey N. Masters
Keyword(s):  
Mycophenolic Acid ◽  
Species Differences ◽  
Cultured Hepatocytes ◽  
Efflux Transport

Glucuronidation and Subsequent Biliary Excretion of Mycophenolic Acid in Rat Sandwich-cultured Hepatocytes

2014 ◽  
Vol 29 (2) ◽  
pp. 129-134 ◽  
Author(s):  
Kazuhiro Tetsuka ◽  
Nicolas Gerst ◽  
Kouichi Tamura ◽  
Jeffrey N. Masters
Keyword(s):  
Mycophenolic Acid ◽  
Biliary Excretion ◽  
Cultured Hepatocytes

Species differences in metabolism of ketotifen in rat, rabbit and man: Demonstration of similar pathways and in cultured hepatocytes

Life Sciences ◽  
1987 ◽  
Vol 40 (9) ◽  
pp. 883-890 ◽  
Author(s):  
J.F. Le Bigot ◽  
J.M. Begue ◽  
J.R. Kiechel ◽  
A. Guillouzo
Keyword(s):  
Species Differences ◽  
Cultured Hepatocytes

MRP4 is responsible for the efflux transport of mycophenolic acid β-d glucuronide (MPAG) from hepatocytes to blood

Xenobiotica ◽  
2020 ◽  
Vol 51 (1) ◽  
pp. 105-114
Author(s):  
Joseph Berthier ◽  
Mehdi Benmameri ◽  
François-Ludovic Sauvage ◽  
Gabin Fabre ◽  
Benjamin Chantemargue ◽  
...  
Keyword(s):  
Mycophenolic Acid ◽  
Efflux Transport

Species differences in the response of cultured hepatocytes to phthalate esters

1986 ◽  
Vol 24 (6-7) ◽  
pp. 799-800 ◽  
Author(s):  
D.J. Benford ◽  
S. Patel ◽  
H.J. Reavy ◽  
A. Mitchell ◽  
N.J. Sarginson
Keyword(s):  
Species Differences ◽  
Phthalate Esters ◽  
Cultured Hepatocytes

AN INVESTIGATION OF HUMAN AND RAT LIVER MICROSOMAL MYCOPHENOLIC ACID GLUCURONIDATION: EVIDENCE FOR A PRINCIPAL ROLE OF UGT1A ENZYMES AND SPECIES DIFFERENCES IN UGT1A SPECIFICITY

2005 ◽  
Vol 33 (10) ◽  
pp. 1513-1520 ◽  
Author(s):  
Kristini K. Miles ◽  
Stephan T. Stern ◽  
Philip C. Smith ◽  
Fay K. Kessler ◽  
Shazia Ali ◽  
...  
Keyword(s):  
Rat Liver ◽  
Mycophenolic Acid ◽  
Species Differences ◽  
Principal Role

Scanning Electron Microscopy of Fish Scales as an Adjunctive Aid in Speciation

1972 ◽  
Vol 30 ◽  
pp. 394-395
Author(s):  
Edward D. DeLamater ◽  
Walter R. Courtenay ◽  
Cecil Whitaker
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Lateral Line ◽  
Species Differences ◽  
Fish Scale ◽  
Fish Scales ◽  
Anterior Border ◽  
The University ◽  
Multiple Holes ◽  
Scanning Electron

Comparative scanning electron microscopy studies of fish scales of different orders, families, genera and species within genera have demonstrated differences which warrant elaboration. These differences in detail appear to be sufficient to act as “fingerprints”, at least, for family differences. To date, the lateral line scales have been primarily studied. These demonstrate differences in the lateral line canals; the pattern of ridging with or without secondary protuberances along the edges; the pattern of spines or their absence on the anterior border of the scales; the presence or absence of single or multiple holes on the ventral and dorsal sides of the lateral line canal covers. The distances between the ridges in the pattern appear likewise to be important.A statement of fish scale structure and a comparison of family and species differences will be presented.The authors wish to thank Dr. Donald Marzalek and Mr. Wallace Charm of the Marine and Atmospheric Laboratory of the University of Miami and Dr. Sheldon Moll and Dr. Richard Turnage of AMR for their exhaustive help in these preliminary studies.

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