Cytoprotective role of astaxanthin against glycated protein/iron chelate-induced toxicity in human umbilical vein endothelial cells

2009 ◽  
Vol 24 (1) ◽  
pp. 54-59 ◽  
Author(s):  
Ikuo Nishigaki ◽  
Peramaiyan Rajendran ◽  
Ramachandran Venugopal ◽  
Gnapathy Ekambaram ◽  
Dhanapal Sakthisekaran ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Umbilical Vein ◽  
Iron Chelate ◽  
Human Umbilical Vein ◽  
Glycated Protein ◽  
Umbilical Vein Endothelial Cells

Protective Effect of Phyllanthus polyphyllus on Human Umbilical Vein Endothelial Cells against Glycated Protein-Iron Chelate Induced Toxicity

2007 ◽  
Vol 7 (6) ◽  
pp. 961-968
Author(s):  
Rajkapoor Balasubram ◽  
Venugopal Ramachandr ◽  
Sakthisekaran Dhanapal ◽  
Zhang Hao Qian ◽  
Ikuo Nishigaki
Keyword(s):  
Endothelial Cells ◽  
Protective Effect ◽  
Umbilical Vein ◽  
Iron Chelate ◽  
Human Umbilical Vein ◽  
Glycated Protein ◽  
Umbilical Vein Endothelial Cells

Protective Effect of Fresh Apple Skin Extract on Human Umbilical Vein Endothelial Cells Against Glycated Protein-iron Chelate Induced Toxicity

2007 ◽  
Vol 2 (2) ◽  
pp. 34-42
Author(s):  
Ikuo Nishigaki ◽  
Balasubramanian Rajkapoor ◽  
Ramachandran Venugopal ◽  
Palaniyandi Senthilnat ◽  
Hao Qian Zhang ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Protective Effect ◽  
Umbilical Vein ◽  
Skin Extract ◽  
Iron Chelate ◽  
Human Umbilical Vein ◽  
Glycated Protein ◽  
Umbilical Vein Endothelial Cells

scholarly journals Effect of Extract of Pomegranate (Punica granatum L.) on Glycated Protein-iron Chelate-induced Toxicity: An In Vitro Study on Human Umbilical-vein Endothelial Cells

2008 ◽  
Vol 54 (4) ◽  
pp. 441-449 ◽  
Author(s):  
Ikuo Nishigaki ◽  
Peramaiyan Rajendran ◽  
Ramachandran Venugopal ◽  
Ganapathy Ekambaram ◽  
Dhanapal Sakthisekaran ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Umbilical Vein ◽  
In Vitro Study ◽  
Punica Granatum ◽  
Iron Chelate ◽  
Human Umbilical Vein ◽  
Glycated Protein ◽  
Umbilical Vein Endothelial Cells ◽  
Punica Granatum L

scholarly journals The role of miR-146a on NF-κB expression level in human umbilical vein endothelial cells under hyperglycemic condition

2016 ◽  
Vol 117 (07) ◽  
pp. 376-380 ◽  
Author(s):  
K. Kamali ◽  
E. Salmani Korjan ◽  
E. Eftekhar ◽  
K. Malekzadeh ◽  
F. Ghadiri Soufi
Keyword(s):  
Endothelial Cells ◽  
Umbilical Vein ◽  
Expression Level ◽  
Human Umbilical Vein ◽  
Umbilical Vein Endothelial Cells

Rapamycin inhibits oxidative/nitrosative stress and enhances angiogenesis in high glucose-treated human umbilical vein endothelial cells: Role of autophagy

2017 ◽  
Vol 93 ◽  
pp. 885-894 ◽  
Author(s):  
Aysa Rezabakhsh ◽  
Mahdi Ahmadi ◽  
Majid Khaksar ◽  
Azadeh Montaseri ◽  
Hassan Malekinejad ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
High Glucose ◽  
Nitrosative Stress ◽  
Umbilical Vein ◽  
Human Umbilical Vein ◽  
Umbilical Vein Endothelial Cells

MODULATION of PROSTACYCLIN PRODUCTION BY HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS WITH ECGF/HEPARIN MEDIUM : ROLE OF CELLULAR DENSITY AT CONFLUENCE

1987 ◽  
Author(s):  
O BOUTHERIN-FALSON ◽  
N BLAES
Keyword(s):  
Endothelial Cells ◽  
Endothelial Cell ◽  
Growth Factor ◽  
Umbilical Vein ◽  
Calf Serum ◽  
Lower Amount ◽  
Endothelial Cell Proliferation ◽  
Human Umbilical Vein ◽  
Umbilical Vein Endothelial Cells

Prostacyclin (PGI2) is a major product of arachidonic acid metabolism in vascular endothelial cells. In addition to the role of exogenous agents, its production could be modulated by culture conditions : proliferative state, medium renewal, subcultivation... The use of endothelial cell growth factor (ECGF) associated with heparin has been shown to improve human endothelial cell proliferation. Here we report that human umbilical vein endothelial cells (HUVEC) grown in that medium produce less prostacyclin than without growth factor.HUVEC were cultured in RPMI-199 1:1 + 20% fetal calf serum, added or not with ECGF (Bovine hypothalamus extract BTI Cambridge, 24 ug/ml) and heparin (from porcine intestinal mucosa, Signa, 90 ug/ml). After 4 days in culture, medium was removed and replaced by Tyrode Hepes buffer and basal production was measured after 20 min. Cells were then submitted to 5 min thrombin to assess PGI2 production in stimulated conditions. PGI2 production was estimated by specific radioimmunoassay for 6 keto PGFjalpha. For each point, cell number in the culture was counted after Trypsin EDTA treatment. In the present study, cells grown in ECGF-heparin medium produce lower amount of PGI2, compared to heparin or control medium. This result was observed in both basal and stimulated conditions. For each medium (ECGF-heparin, heparin, control), correlations between PGI2 production per cell and log cell density were shown to be significantly negative.These observations suggest that ECGF effect on PGI2 production could be a consequence of its growth factor activity, notably by the fact that it leads to an endothelial monolayer made of more numerous cells. Since it is now suggested by a number of clinical observations that PGI2 is rather produced in pathological conditions, culture models showing a weak production of PGI2 appear in that connection doser to the physiological conditions.

The Role of Laminin α4 in Human Umbilical Vein Endothelial Cells and Pathological Mechanism of Preeclampsia

2015 ◽  
Vol 22 (8) ◽  
pp. 969-979 ◽  
Author(s):  
Nan Shan ◽  
Xuemei Zhang ◽  
Xiaoqiu Xiao ◽  
Hua Zhang ◽  
Ying Chen ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Umbilical Vein ◽  
Human Umbilical Vein ◽  
Pathological Mechanism ◽  
Umbilical Vein Endothelial Cells
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