Structural elucidation ofN-oxidized clemastine metabolites by liquid chromatography/tandem mass spectrometry and the use ofCunninghamella elegansto facilitate drug metabolite identification

Annica Tevell Åberg; Helena Löfgren; Ulf Bondesson; Mikael Hedeland

doi:10.1002/rcm.4535

Structural elucidation ofN-oxidized clemastine metabolites by liquid chromatography/tandem mass spectrometry and the use ofCunninghamella elegansto facilitate drug metabolite identification

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.4535 ◽

2010 ◽

Vol 24 (10) ◽

pp. 1447-1456 ◽

Cited By ~ 11

Author(s):

Annica Tevell Åberg ◽

Helena Löfgren ◽

Ulf Bondesson ◽

Mikael Hedeland

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Metabolite Identification ◽

Structural Elucidation ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Drug Metabolite ◽

Liquid Chromatography Tandem Mass

Download Full-text

Metabolite identification of a new antitumor agent icotinib in rats using liquid chromatography/tandem mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.3599 ◽

2008 ◽

Vol 22 (14) ◽

pp. 2176-2184 ◽

Cited By ~ 8

Author(s):

Zhongmin Guan ◽

Xiaoyan Chen ◽

Yinxiang Wang ◽

Dafang Zhong

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Metabolite Identification ◽

Antitumor Agent ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

Download Full-text

Metabolite identification of liguzinediol in dogs by ultra-flow liquid chromatography/tandem mass spectrometry

Journal of Chromatography B ◽

10.1016/j.jchromb.2014.06.029 ◽

2014 ◽

Vol 967 ◽

pp. 63-68 ◽

Cited By ~ 4

Author(s):

Chen-xiao Shan ◽

Wei Li ◽

Hong-mei Wen ◽

Xin-zhi Wang ◽

Xiao-wen Zhu ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Metabolite Identification ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

Download Full-text

Liquid chromatography tandem mass spectrometry method for the quantitation of mycophenolate mofetil in human plasma: Application to a bioequivalence study and metabolite identification

Journal of Separation Science ◽

10.1002/jssc.201500779 ◽

2015 ◽

Vol 38 (20) ◽

pp. 3533-3544 ◽

Cited By ~ 2

Author(s):

Pankaj Partani ◽

Saurabh Manaswita Verma ◽

Tausif Monif

Keyword(s):

Mass Spectrometry ◽

Mycophenolate Mofetil ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Metabolite Identification ◽

Bioequivalence Study ◽

Tandem Mass ◽

Spectrometry Method ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

Download Full-text

In vitro and in vivo metabolite identification of a novel benzimidazole compound ZLN005 by liquid chromatography/tandem mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.8060 ◽

2018 ◽

Vol 32 (6) ◽

pp. 480-488 ◽

Cited By ~ 2

Author(s):

Wenchao Sun ◽

Khoa Dinh Nguyen ◽

William L. Fitch ◽

Samuel D. Banister ◽

Hongxiang Tang ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Metabolite Identification ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

Download Full-text

Structural elucidation of the metabolites of lapachol in rats by liquid chromatography–tandem mass spectrometry

Journal of Chromatography B ◽

10.1016/j.jchromb.2013.11.024 ◽

2014 ◽

Vol 944 ◽

pp. 128-135 ◽

Cited By ~ 7

Author(s):

Lu Bai ◽

Ying Han ◽

Jinfeng Yao ◽

Xiaorong Li ◽

Yuhang Li ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Structural Elucidation ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

Download Full-text

Pharmacokinetics and metabolite identification of a novel VEGFR-2 and Src dual inhibitor 6-chloro-2-methoxy-N-(2-methoxybenzyl) acridin-9-amine in rats by liquid chromatography tandem mass spectrometry

Talanta ◽

10.1016/j.talanta.2011.11.061 ◽

2012 ◽

Vol 89 ◽

pp. 70-76 ◽

Cited By ~ 14

Author(s):

Yibao Jin ◽

Xudong Luan ◽

Hongxia Liu ◽

Chunmei Gao ◽

Shangfu Li ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Metabolite Identification ◽

Tandem Mass ◽

Dual Inhibitor ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

Download Full-text

Analysis of trans-2,6-difluoro-4′-(N,N-dimethylamino)stilbene (DFS) in biological samples by liquid chromatography-tandem mass spectrometry: metabolite identification and pharmacokinetics

Analytical and Bioanalytical Chemistry ◽

10.1007/s00216-015-8893-x ◽

2015 ◽

Vol 407 (24) ◽

pp. 7319-7332 ◽

Cited By ~ 14

Author(s):

Samuel Chao Ming Yeo ◽

Vitaliy M. Sviripa ◽

Meng Huang ◽

Liliia Kril ◽

David S. Watt ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Biological Samples ◽

Metabolite Identification ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

Download Full-text

Structural elucidation of in vivo and in vitro metabolites of anisodine by liquid chromatography–tandem mass spectrometry

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2007.01.038 ◽

2007 ◽

Vol 44 (3) ◽

pp. 773-778 ◽

Cited By ~ 11

Author(s):

Huaixia Chen ◽

Yong Chen ◽

Peng Du ◽

Fengmei Han

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Structural Elucidation ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

Download Full-text

Metabolite identification of a new tyrosine kinase inhibitor, HM781-36B, and a pharmacokinetic study by liquid chromatography/tandem mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.6559 ◽

2013 ◽

Vol 27 (11) ◽

pp. 1183-1195 ◽

Cited By ~ 5

Author(s):

Eunyoung Kim ◽

Hankyong Kim ◽

Kweehyun Suh ◽

Sechang Kwon ◽

Gwansun Lee ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Tyrosine Kinase Inhibitor ◽

Pharmacokinetic Study ◽

Kinase Inhibitor ◽

Metabolite Identification ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

Download Full-text

Identification and structural elucidation of an unknown impurity in carbamazepine active pharmaceutical ingredient by liquid chromatography–tandem mass spectrometry and semi-preparative chromatographic isolation

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2011.05.030 ◽

2011 ◽

Vol 56 (2) ◽

pp. 423-428 ◽

Cited By ~ 8

Author(s):

Saji Thomas ◽

Chandra S. Mathela ◽

Ashutosh Agarwal ◽

Saroj Kumar Paul

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Active Pharmaceutical Ingredient ◽

Structural Elucidation ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass ◽

Chromatographic Isolation

Download Full-text