Metabolite identification of a new tyrosine kinase inhibitor, HM781-36B, and a pharmacokinetic study by liquid chromatography/tandem mass spectrometry

Eunyoung Kim; Hankyong Kim; Kweehyun Suh; Sechang Kwon; Gwansun Lee; Na Hyun Park; Jongki Hong

doi:10.1002/rcm.6559

Metabolite identification of a new tyrosine kinase inhibitor, HM781-36B, and a pharmacokinetic study by liquid chromatography/tandem mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.6559 ◽

2013 ◽

Vol 27 (11) ◽

pp. 1183-1195 ◽

Cited By ~ 5

Author(s):

Eunyoung Kim ◽

Hankyong Kim ◽

Kweehyun Suh ◽

Sechang Kwon ◽

Gwansun Lee ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Tyrosine Kinase Inhibitor ◽

Pharmacokinetic Study ◽

Kinase Inhibitor ◽

Metabolite Identification ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

Quantification of the tyrosine kinase inhibitor erlotinib in human scalp hair by liquid chromatography-tandem mass spectrometry: Pitfalls for clinical application

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2019.04.031 ◽

2019 ◽

Vol 172 ◽

pp. 175-182 ◽

Cited By ~ 2

Author(s):

C. Louwrens Braal ◽

G.D. Marijn Veerman ◽

Robert Peric ◽

Joachim G.J.V. Aerts ◽

Ron H.J. Mathijssen ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Kinase Inhibitor ◽

Scalp Hair ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

A quick approach for medetomidine enantiomer determination in dog plasma by chiral liquid chromatography–tandem mass spectrometry and application to a pharmacokinetic study

Drug Testing and Analysis ◽

10.1002/dta.3015 ◽

2021 ◽

Author(s):

Anisa Bardhi ◽

Anna Zaghini ◽

Olivier Levionnois ◽

Andrea Barbarossa

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Pharmacokinetic Study ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Dog Plasma ◽

Liquid Chromatography Tandem Mass

Simultaneous determination of 3‐ n ‐butylphthalide and its metabolite 10‐hydroxy‐butylphthalide in rat plasma by using liquid chromatography tandem mass spectrometry and application to a pharmacokinetic study

Biomedical Chromatography ◽

10.1002/bmc.5184 ◽

2021 ◽

Author(s):

Li‐Shu Lin ◽

Li‐Ling Lin ◽

Tao Lin ◽

Yan‐An Wu

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Simultaneous Determination ◽

Pharmacokinetic Study ◽

Rat Plasma ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

Development and validation of a liquid chromatography–tandem mass spectrometry assay for the simultaneous quantitation of prednisolone and dipyridamole in human plasma and its application in a pharmacokinetic study

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2009.02.017 ◽

2009 ◽

Vol 49 (5) ◽

pp. 1241-1249 ◽

Cited By ~ 9

Author(s):

Mei Chen ◽

Camille Granvil ◽

Qin C. Ji ◽

Zhi-Yi Zhang ◽

Mahesh V. Padval ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Human Plasma ◽

Pharmacokinetic Study ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass ◽

Development And Validation ◽

Mass Spectrometry Assay

Quantitation of unbound sunitinib and its metaboliteN-desethyl sunitinib (SU12662) in human plasma by equilibrium dialysis and liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study

Biomedical Chromatography ◽

10.1002/bmc.2697 ◽

2012 ◽

Vol 26 (11) ◽

pp. 1315-1324 ◽

Cited By ~ 13

Author(s):

Rana Rais ◽

Ming Zhao ◽

Ping He ◽

Linping Xu ◽

John F. Deeken ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Human Plasma ◽

Pharmacokinetic Study ◽

Equilibrium Dialysis ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass ◽

Mass Spectrometry Application

Simultaneous determination of nalbuphine and its prodrug sebacoly dinalbuphine ester in human plasma by ultra-performance liquid chromatography-tandem mass spectrometry and its application to pharmacokinetic study in humans

Biomedical Chromatography ◽

10.1002/bmc.2867 ◽

2013 ◽

Vol 27 (7) ◽

pp. 831-837 ◽

Cited By ~ 9

Author(s):

Pei-Wei Huang ◽

Hung-Ta Liu ◽

Cheng-Huei Hsiong ◽

Li-Heng Pao ◽

Chih-Cherng Lu ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Simultaneous Determination ◽

Pharmacokinetic Study ◽

Ultra Performance Liquid Chromatography ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

Simultaneous Analysis of Quercetin and Naringenin in Rat Plasma by Liquid Chromatography–Tandem Mass Spectrometry: Application to a Pharmacokinetic Study After Oral Administration

Journal of Chromatographic Science ◽

10.1093/chromsci/bmw079 ◽

2016 ◽

Vol 54 (8) ◽

pp. 1359-1364 ◽

Cited By ~ 3

Author(s):

Boran Ni ◽

Sali Cao ◽

Lijun Feng ◽

Xingbin Yin ◽

Wenping Wang ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Oral Administration ◽

Pharmacokinetic Study ◽

Rat Plasma ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass ◽

Mass Spectrometry Application

High-performance liquid chromatography–tandem mass spectrometry for the determination of pidotimod in human plasma and its application to a pharmacokinetic study

Journal of Chromatography B ◽

10.1016/j.jchromb.2009.06.038 ◽

2009 ◽

Vol 877 (24) ◽

pp. 2566-2570 ◽

Cited By ~ 5

Author(s):

Yi Zhang ◽

Zhili Xiong ◽

Feng Qin ◽

Shan Lu ◽

Wei Liu ◽

...

Keyword(s):

Mass Spectrometry ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Pharmacokinetic Study ◽

High Performance ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

Liquid chromatography–tandem mass spectrometry method for the estimation of adefovir in human plasma: Application to a pharmacokinetic study

Journal of Pharmaceutical Analysis ◽

10.1016/j.jpha.2014.08.002 ◽

2015 ◽

Vol 5 (3) ◽

pp. 190-199 ◽

Cited By ~ 3

Author(s):

Dipanjan Goswami ◽

Sanjay Gurule ◽

Arabinda Saha ◽

Poonam Vats ◽

Arshad Khuroo ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Human Plasma ◽

Pharmacokinetic Study ◽

Tandem Mass ◽

Spectrometry Method ◽

Mass Spectrometry Method ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

Liquid chromatography–tandem mass spectrometry method for determining tolvaptan and its nine metabolites in rat serum: application to a pharmacokinetic study

Archives of Pharmacal Research ◽

10.1007/s12272-014-0352-2 ◽

2014 ◽

Vol 37 (12) ◽

pp. 1578-1587 ◽

Cited By ~ 9

Author(s):

Masayuki Furukawa ◽

Kenichi Miyata ◽

Chie Kawasome ◽

Yoshiko Himeda ◽

Kenji Takeuchi ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Pharmacokinetic Study ◽

Tandem Mass ◽

Spectrometry Method ◽

Rat Serum ◽

Mass Spectrometry Method ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass