scholarly journals Desorption atmospheric pressure photoionization and direct analysis in real time coupled with travelling wave ion mobility mass spectrometry

2014 ◽  
Vol 28 (21) ◽  
pp. 2325-2336 ◽  
Author(s):  
Riikka-Marjaana Räsänen ◽  
Prabha Dwivedi ◽  
Facundo M. Fernández ◽  
Tiina J. Kauppila
Keyword(s):  
Mass Spectrometry ◽  
Real Time ◽  
Ion Mobility ◽  
Atmospheric Pressure ◽  
Direct Analysis ◽  
Travelling Wave ◽  
Ion Mobility Mass Spectrometry ◽  
Atmospheric Pressure Photoionization

scholarly journals Automated 16-Plex Plasma Proteomics with Real-Time Search and Ion Mobility Mass Spectrometry Enables Large-Scale Profiling in Naked Mole-Rats and Mice

2021 ◽  
Vol 20 (2) ◽  
pp. 1280-1295
Author(s):  
Aleksandr Gaun ◽  
Kaitlyn N. Lewis Hardell ◽  
Niclas Olsson ◽  
Jonathon J. O’Brien ◽  
Sudha Gollapudi ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Real Time ◽  
Ion Mobility ◽  
Large Scale ◽  
Ion Mobility Mass Spectrometry ◽  
Plasma Proteomics ◽  
Rats And Mice

scholarly journals Amphitrite: A program for processing travelling wave ion mobility mass spectrometry data

2013 ◽  
Vol 345-347 ◽  
pp. 54-62 ◽  
Author(s):  
Ganesh N. Sivalingam ◽  
Jun Yan ◽  
Harpal Sahota ◽  
Konstantinos Thalassinos
Keyword(s):  
Mass Spectrometry ◽  
Ion Mobility ◽  
Travelling Wave ◽  
Mass Spectrometry Data ◽  
Ion Mobility Mass Spectrometry

Pulsed Nano-ESI Atmospheric-Pressure Ion Mobility Mass Spectrometry with Enhanced Ion Sampling

2016 ◽  
Vol 88 (23) ◽  
pp. 11767-11773 ◽  
Author(s):  
William P. McMahon ◽  
Arjuna Subramanian ◽  
Carina S. Minardi ◽  
Rohan Dalvi ◽  
Kaveh Jorabchi
Keyword(s):  
Mass Spectrometry ◽  
Ion Mobility ◽  
Atmospheric Pressure ◽  
Ion Mobility Mass Spectrometry

Characterisation of Calmodulin Structural Transitions by Ion Mobility Mass Spectrometry

2012 ◽  
Vol 65 (5) ◽  
pp. 504 ◽  
Author(s):  
Antonio N. Calabrese ◽  
Lauren A. Speechley ◽  
Tara L. Pukala
Keyword(s):  
Mass Spectrometry ◽  
Cross Section ◽  
Cross Sections ◽  
Ion Mobility ◽  
Collision Cross Section ◽  
Travelling Wave ◽  
Ion Mobility Mass Spectrometry ◽  
Structural Transitions ◽  
Calmodulin Binding ◽  
Negative Mode

This study demonstrates the ability of travelling wave ion mobility-mass spectrometry to measure collision cross-sections of ions in the negative mode, using a calibration based approach. Here, negative mode ion mobility-mass spectrometry was utilised to understand structural transitions of calmodulin upon Ca2+ binding and complexation with model peptides melittin and the plasma membrane Ca2+ pump C20W peptide. Coexisting calmodulin conformers were distinguished on the basis of their mass and cross-section, and identified as relatively folded and unfolded populations, with good agreement in collision cross-section to known calmodulin geometries. Titration of calcium tartrate to physiologically relevant Ca2+ levels provided evidence for intermediately metalated species during the transition from apo- to holo-calmodulin, with collision cross-section measurements indicating that higher Ca2+ occupancy is correlated with more compact structures. The binding of two representative peptides which exemplify canonical compact (melittin) and extended (C20W) peptide-calmodulin binding models has also been interrogated by ion mobility mass spectrometry. Peptide binding to calmodulin involves intermediates with metalation states from 1–4 Ca2+, which demonstrate relatively collapsed structures, suggesting neither the existence of holo-calmodulin or a pre-folded calmodulin conformation is a prerequisite for binding target peptides or proteins. The biological importance of the different metal unsaturated calmodulin complexes, if any, is yet to be understood.

scholarly journals Direct observation of C60− nano-ion gas phase ozonation via ion mobility-mass spectrometry

2019 ◽  
Vol 21 (20) ◽  
pp. 10470-10476 ◽  
Author(s):  
Chenxi Li ◽  
Christopher J. Hogan Jr
Keyword(s):  
Mass Spectrometry ◽  
Gas Phase ◽  
Ion Mobility ◽  
Atmospheric Pressure ◽  
Reaction Rates ◽  
Ion Mobility Mass Spectrometry ◽  
Mobility Analysis ◽  
Differential Mobility ◽  
Differential Mobility Analysis

Atmospheric pressure differential mobility analysis-mass spectrometry facilitates determination of nano-ion-neutral reaction rates approaching the collision controlled limit.

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