scholarly journals Automated 16-Plex Plasma Proteomics with Real-Time Search and Ion Mobility Mass Spectrometry Enables Large-Scale Profiling in Naked Mole-Rats and Mice

2021 ◽  
Vol 20 (2) ◽  
pp. 1280-1295
Author(s):  
Aleksandr Gaun ◽  
Kaitlyn N. Lewis Hardell ◽  
Niclas Olsson ◽  
Jonathon J. O’Brien ◽  
Sudha Gollapudi ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Real Time ◽  
Ion Mobility ◽  
Large Scale ◽  
Ion Mobility Mass Spectrometry ◽  
Plasma Proteomics ◽  
Rats And Mice

Real time pharmaceutical reaction monitoring by electrospray ion mobility-mass spectrometry

2013 ◽  
Vol 336 ◽  
pp. 27-36 ◽  
Author(s):  
Kristyn M. Roscioli ◽  
Xing Zhang ◽  
Shelly X. Li ◽  
Gilles H. Goetz ◽  
Guilong Cheng ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Real Time ◽  
Ion Mobility ◽  
Ion Mobility Mass Spectrometry ◽  
Reaction Monitoring

Real-time reaction monitoring using ion mobility-mass spectrometry

The Analyst ◽  
2011 ◽  
Vol 136 (8) ◽  
pp. 1728 ◽  
Author(s):  
Emma L. Harry ◽  
Anthony W. T. Bristow ◽  
Ian D. Wilson ◽  
Colin S. Creaser
Keyword(s):  
Mass Spectrometry ◽  
Real Time ◽  
Ion Mobility ◽  
Ion Mobility Mass Spectrometry ◽  
Reaction Monitoring

scholarly journals Large-Scale Structural Characterization of Drug and Drug-Like Compounds by High-Throughput Ion Mobility-Mass Spectrometry

2017 ◽  
Vol 89 (17) ◽  
pp. 9023-9030 ◽  
Author(s):  
Kelly M. Hines ◽  
Dylan H. Ross ◽  
Kimberly L. Davidson ◽  
Matthew F. Bush ◽  
Libin Xu
Keyword(s):  
Mass Spectrometry ◽  
High Throughput ◽  
Structural Characterization ◽  
Ion Mobility ◽  
Large Scale ◽  
Ion Mobility Mass Spectrometry

Large-Scale Prediction of Collision Cross-Section Values for Metabolites in Ion Mobility-Mass Spectrometry

2016 ◽  
Vol 88 (22) ◽  
pp. 11084-11091 ◽  
Author(s):  
Zhiwei Zhou ◽  
Xiaotao Shen ◽  
Jia Tu ◽  
Zheng-Jiang Zhu
Keyword(s):  
Mass Spectrometry ◽  
Cross Section ◽  
Ion Mobility ◽  
Large Scale ◽  
Collision Cross Section ◽  
Ion Mobility Mass Spectrometry

Rapid Diagnosis of Parkinson’s Disease from Sebum using Paper Spray Ionisation Ion Mobility Mass Spectrometry

2020 ◽  
Author(s):  
Depanjan Sarkar ◽  
Drupad Trivedi ◽  
Eleanor Sinclair ◽  
Sze Hway Lim ◽  
Caitlin Walton-Doyle ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Ion Mobility ◽  
Neurodegenerative Disorder ◽  
Treatment Options ◽  
Ion Mobility Mass Spectrometry ◽  
Paper Spray ◽  
Molecular Features ◽  
Validation Set

Parkinson’s disease (PD) is the second most common neurodegenerative disorder for which identification of robust biomarkers to complement clinical PD diagnosis would accelerate treatment options and help to stratify disease progression. Here we demonstrate the use of paper spray ionisation coupled with ion mobility mass spectrometry (PSI IM-MS) to determine diagnostic molecular features of PD in sebum. PSI IM-MS was performed directly from skin swabs, collected from 34 people with PD and 30 matched control subjects as a training set and a further 91 samples from 5 different collection sites as a validation set. PSI IM-MS elucidates ~ 4200 features from each individual and we report two classes of lipids (namely phosphatidylcholine and cardiolipin) that differ significantly in the sebum of people with PD. Putative metabolite annotations are obtained using tandem mass spectrometry experiments combined with accurate mass measurements. Sample preparation and PSI IM-MS analysis and diagnosis can be performed ~5 minutes per sample offering a new route to for rapid and inexpensive confirmatory diagnosis of this disease.

P‐97: Separation of Isomeric OLED Materials Using Ion Mobility‐Mass Spectrometry (IM‐MS)

2021 ◽  
Vol 52 (1) ◽  
pp. 1444-1447
Author(s):  
Hirotaka Shioji ◽  
Azusa Uematsu ◽  
Motoshi Onoda ◽  
Keiko Matsuda ◽  
Keisuke Sawada ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Ion Mobility ◽  
Ion Mobility Mass Spectrometry
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