Rapid oligonucleotide drug impurity determination by direct spectral comparison of ion-pair reversed-phase high-performance liquid chromatography electrospray ionization mass spectrometry data

Stilianos G. Roussis; Charlie Koch; Daniel Capaldi; Claus Rentel

doi:10.1002/rcm.8125

Rapid oligonucleotide drug impurity determination by direct spectral comparison of ion-pair reversed-phase high-performance liquid chromatography electrospray ionization mass spectrometry data

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.8125 ◽

2018 ◽

Vol 32 (14) ◽

pp. 1099-1106 ◽

Cited By ~ 6

Author(s):

Stilianos G. Roussis ◽

Charlie Koch ◽

Daniel Capaldi ◽

Claus Rentel

Keyword(s):

Mass Spectrometry ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

High Performance ◽

Reversed Phase ◽

Ion Pair ◽

Mass Spectrometry Data ◽

Ionization Mass ◽

Spectral Comparison ◽

Impurity Determination

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Separation of N-nitrosoamino acids by C18 reversed-phase ion-pair high-performance liquid chromatography and compatible detection by electrospray ionization mass spectrometry

Journal of Chromatography A ◽

10.1016/s0021-9673(99)00610-x ◽

1999 ◽

Vol 849 (2) ◽

pp. 389-402 ◽

Cited By ~ 8

Author(s):

C.F. Cheng ◽

C.W. Tsang

Keyword(s):

Mass Spectrometry ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Electrospray Ionization ◽

Electrospray Ionization Mass Spectrometry ◽

High Performance ◽

Reversed Phase ◽

Ion Pair ◽

Ionization Mass Spectrometry ◽

Ionization Mass

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Electrospray Ionization Mass Spectrometry Coupled To Reversed-Phase Ion-Pair High-Performance Liquid Chromatography for Quantitation of Sodium Borocaptate and Application To Pharmacokinetic Analysis

Analytical Chemistry ◽

10.1021/ac0112723 ◽

2002 ◽

Vol 74 (10) ◽

pp. 2394-2399 ◽

Cited By ~ 7

Author(s):

Christopher R. Gibson ◽

Alfred E. Staubus ◽

Rolf F. Barth ◽

Weilian Yang ◽

Nan M. Kleinholz ◽

...

Keyword(s):

Mass Spectrometry ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Electrospray Ionization ◽

Electrospray Ionization Mass Spectrometry ◽

High Performance ◽

Reversed Phase ◽

Ion Pair ◽

Pharmacokinetic Analysis ◽

Ionization Mass

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Mutation scanning by ion-pair reversed-phase high-performance liquid chromatography-electrospray ionization mass spectrometry (ICEMS)

Human Mutation ◽

10.1002/humu.10155 ◽

2002 ◽

Vol 21 (1) ◽

pp. 86-95 ◽

Cited By ~ 21

Author(s):

Herbert Oberacher ◽

Christian G. Huber ◽

Peter J. Oefner

Keyword(s):

Mass Spectrometry ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Electrospray Ionization ◽

Electrospray Ionization Mass Spectrometry ◽

High Performance ◽

Reversed Phase ◽

Ion Pair ◽

Ionization Mass ◽

Mutation Scanning

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Separation, detection, and identification of peptides by ion-pair reversed-phase high-performance liquid chromatography-electrospray ionization mass spectrometry at high and low pH

Journal of Chromatography A ◽

10.1016/j.chroma.2005.03.121 ◽

2005 ◽

Vol 1079 (1-2) ◽

pp. 274-286 ◽

Cited By ~ 73

Author(s):

Hansjörg Toll ◽

Herbert Oberacher ◽

Remco Swart ◽

Christian G. Huber

Keyword(s):

Mass Spectrometry ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Electrospray Ionization ◽

High Performance ◽

Reversed Phase ◽

Ion Pair ◽

Low Ph ◽

Ionization Mass ◽

Detection And Identification

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Analysis of native and chemically modified oligonucleotides by tandem ion-pair reversed-phase high-performance liquid chromatography/electrospray ionization mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.959 ◽

2003 ◽

Vol 17 (7) ◽

pp. 646-653 ◽

Cited By ~ 79

Author(s):

Kenneth J. Fountain ◽

Martin Gilar ◽

John C. Gebler

Keyword(s):

Mass Spectrometry ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Electrospray Ionization ◽

High Performance ◽

Reversed Phase ◽

Ion Pair ◽

Ionization Mass ◽

Modified Oligonucleotides ◽

Chemically Modified

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Analysis of DNA methylation by tandem ion-pair reversed-phase high-performance liquid chromatography/electrospray ionization mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.1675 ◽

2004 ◽

Vol 18 (22) ◽

pp. 2773-2778 ◽

Cited By ~ 10

Author(s):

Huayong Chen ◽

Wenbing Zhang ◽

Renfang Song ◽

Huimin Ma ◽

Yulian Dong ◽

...

Keyword(s):

Mass Spectrometry ◽

Dna Methylation ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Electrospray Ionization ◽

Electrospray Ionization Mass Spectrometry ◽

High Performance ◽

Reversed Phase ◽

Ion Pair ◽

Ionization Mass

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Characterization of G-rich and T-Rich Oligonucleotides Using Ion-Pair Reversed-Phase High-Performance Liquid Chromatography/Tandem Electrospray Ionization Mass Spectrometry

European Journal of Mass Spectrometry ◽

10.1255/ejms.666 ◽

2004 ◽

Vol 10 (5) ◽

pp. 705-713 ◽

Cited By ~ 6

Author(s):

Renfang Song ◽

Wenbing Zhang ◽

Huayong Chen ◽

Huimin Ma ◽

Yulian Dong ◽

...

Keyword(s):

Mass Spectrometry ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Electrospray Ionization ◽

Electrospray Ionization Mass Spectrometry ◽

High Performance ◽

Reversed Phase ◽

Ion Pair ◽

Ionization Mass

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Development of an analytical reversed-phase high-performance liquid chromatography–electrospray ionization mass spectrometry method for characterization of recombinant antibodies

Journal of Chromatography A ◽

10.1016/s0021-9673(04)01410-4 ◽

2004 ◽

Vol 1053 (1-2) ◽

pp. 299-305 ◽

Cited By ~ 70

Author(s):

T DILLON ◽

P BONDARENKO ◽

M SPEEDRICCI

Keyword(s):

Mass Spectrometry ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Electrospray Ionization ◽

High Performance ◽

Recombinant Antibodies ◽

Reversed Phase ◽

Ionization Mass ◽

Spectrometry Method

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Kinetics of appearance of hemorphins from bovine hemoglobin peptic hydrolysates by a direct coupling of reversed-phase high-performance liquid chromatography and electrospray ionization mass spectrometry

Journal of Chromatography A ◽

10.1016/s0021-9673(99)01353-9 ◽

2000 ◽

Vol 873 (2) ◽

pp. 185-194 ◽

Cited By ~ 11

Author(s):

Renato Froidevaux ◽

Brigitte Lignot ◽

Naima Nedjar-Arroume ◽

Didier Guillochon ◽

Bernadette Coddeville ◽

...

Keyword(s):

Mass Spectrometry ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Electrospray Ionization ◽

Electrospray Ionization Mass Spectrometry ◽

High Performance ◽

Reversed Phase ◽

Bovine Hemoglobin ◽

Ionization Mass ◽

Kinetics Of

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Cutaneous water loss and sphingolipids in the stratum corneum of house sparrows, Passer domesticus L., from desert and mesic environments as determined by reversed phase high-performance liquid chromatography coupled with atmospheric pressure photospray ionization mass spectrometry

Journal of Experimental Biology ◽

10.1242/jeb.013649 ◽

2008 ◽

Vol 211 (3) ◽

pp. 447-458 ◽

Cited By ~ 19

Author(s):

A. Munoz-Garcia ◽

J. Ro ◽

J. C. Brown ◽

J. B. Williams

Keyword(s):

Mass Spectrometry ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Water Loss ◽

Atmospheric Pressure ◽

High Performance ◽

Passer Domesticus ◽

Reversed Phase ◽

Ionization Mass ◽

House Sparrows

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