scholarly journals Fluorescence Imaging: Bright Far-Red/Near-Infrared Conjugated Polymer Nanoparticles for In Vivo Bioimaging (Small 18/2013)

Small ◽  
2013 ◽  
Vol 9 (18) ◽  
pp. 3092-3092 ◽  
Author(s):  
Dan Ding ◽  
Jie Liu ◽  
Guangxue Feng ◽  
Kai Li ◽  
Yong Hu ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Conjugated Polymer ◽  
Near Infrared ◽  
Polymer Nanoparticles ◽  
Conjugated Polymer Nanoparticles

Bright Far-Red/Near-Infrared Conjugated Polymer Nanoparticles for In Vivo Bioimaging

Small ◽  
2013 ◽  
Vol 9 (18) ◽  
pp. 3093-3102 ◽  
Author(s):  
Dan Ding ◽  
Jie Liu ◽  
Guangxue Feng ◽  
Kai Li ◽  
Yong Hu ◽  
...  
Keyword(s):  
Conjugated Polymer ◽  
Near Infrared ◽  
Polymer Nanoparticles ◽  
Conjugated Polymer Nanoparticles

Protein-modified conjugated polymer nanoparticles with strong near-infrared absorption: a novel nanoplatform to design multifunctional nanoprobes for dual-modal photoacoustic and fluorescence imaging

Nanoscale ◽  
2018 ◽  
Vol 10 (42) ◽  
pp. 19742-19748 ◽  
Author(s):  
Duyang Gao ◽  
Pengfei Zhang ◽  
Yubin Liu ◽  
Zonghai Sheng ◽  
Huajie Chen ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Infrared Absorption ◽  
Conjugated Polymer ◽  
Near Infrared ◽  
Polymer Nanoparticles ◽  
Conjugated Polymer Nanoparticles ◽  
General Method

A general method to engineer photoacoustic/fluorescence dual-modal imaging nanoprobes has been proposed based on stable near-infrared conjugated polymer nanoparticles.

scholarly journals New conjugated polymer nanoparticles with high photoluminescence quantum yields for far-red and near infrared fluorescence bioimaging

2020 ◽  
Vol 4 (8) ◽  
pp. 2357-2369 ◽  
Author(s):  
Panagiota Koralli ◽  
Alkmini D. Nega ◽  
Lida Evmorfia Vagiaki ◽  
Aristea Pavlou ◽  
Michael G. Siskos ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Conjugated Polymer ◽  
Near Infrared ◽  
Polymer Nanoparticles ◽  
Quantum Yields ◽  
Near Infrared Fluorescence ◽  
Conjugated Polymer Nanoparticles ◽  
Fluorescence Bioimaging

The development of new aqueous conjugated polymer nanoparticles with high photoluminescence quantum yields (PLQYs) at the far red and near infrared (NIR) spectral regions (>650 nm) as alternative polymer probes for fluorescence imaging is reported.

Theranostic Near-Infrared-Active Conjugated Polymer Nanoparticles

ACS Nano ◽  
2021 ◽  
Author(s):  
Miao Zhao ◽  
Edward Leggett ◽  
Struan Bourke ◽  
Souzana Poursanidou ◽  
Sadie Carter-Searjeant ◽  
...  
Keyword(s):  
Conjugated Polymer ◽  
Near Infrared ◽  
Polymer Nanoparticles ◽  
Conjugated Polymer Nanoparticles

Far-red/near-infrared fluorescent conjugated polymer nanoparticles with size-dependent chirality and cell imaging applications

2015 ◽  
Vol 6 (21) ◽  
pp. 3962-3969 ◽  
Author(s):  
Chunhui Dai ◽  
Dongliang Yang ◽  
Wenjie Zhang ◽  
Biqing Bao ◽  
Yixiang Cheng ◽  
...  
Keyword(s):  
Conjugated Polymer ◽  
Near Infrared ◽  
Cell Imaging ◽  
Polymer Nanoparticles ◽  
Size Dependent ◽  
Conjugated Polymer Nanoparticles ◽  
Nanoparticle Sizes

We prepared a series of novel chiral far-red/near-infrared fluorescent CPNs with different nanoparticle sizes, which show size-dependent chirality and are successfully employed for cell imaging.

scholarly journals Impairing Proliferation of Glioblastoma Multiforme with CD44+ Selective Conjugated Polymer Nanoparticles

2021 ◽  
Author(s):  
Dorota Lubanska ◽  
Sami Alrashed ◽  
Gage T. Mason ◽  
Fatima Nadeem ◽  
Mitchell DiPasquale ◽  
...  
Keyword(s):  
Blood Brain Barrier ◽  
Conjugated Polymer ◽  
Average Diameter ◽  
Polymer Nanoparticles ◽  
Brain Barrier ◽  
Cycle Phase ◽  
Blood Brain ◽  
Brain Barrier Permeability ◽  
Conjugated Polymer Nanoparticles

Glioblastoma is one of the most aggressive types of cancer with median survival of only 15 months. Successful therapy is hampered by the existence of treatment resistant populations of stem-like tumour initiating cells (TICs) and poor blood-brain barrier drug penetration. Therapies capable of effectively targeting the TIC population are in high demand. Here, we synthesize spherical diketopyrrolopyrrole (DPP)-based conjugated polymer nanoparticles (CPNs) with an average diameter of 109 nm. The CPN were designed to include fluorescein-conjugated hyaluronic acid (HA), a ligand for the CD44 receptor present on one population of TICs. We demonstrate blood-brain barrier permeability of this system and concentration and cell cycle phase-dependent selective uptake of HA-CPNs in CD44 positive GBM-patient derived cultures. Interestingly, we found that uptake alone decreases stemness, invasive properties and proliferation of the CD44-TIC population in zebrafish PDX models in vivo. This study is the first to show surface moiety-driven selectivity of conjugated polymer nanoparticles in targeting TIC populations in brain cancer.

Near-Infrared-Absorbing Conjugated Polymer Nanoparticles Loaded with Doxorubicin for Combinatorial Photothermal-Chemotherapy of Cancer

2020 ◽  
Vol 2 (10) ◽  
pp. 4180-4187
Author(s):  
Wei Zhang ◽  
Yi Li ◽  
Lanju Xu ◽  
Dou Wang ◽  
Jing Long ◽  
...  
Keyword(s):  
Conjugated Polymer ◽  
Near Infrared ◽  
Polymer Nanoparticles ◽  
Conjugated Polymer Nanoparticles
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