<p>Steel-concrete composite bridges are currently widely used in highway bridges in China. To reduce durability problems in seasonal freezing region, a design method with given service life is used. The service life is given on the basis of the environment condition and design requirements; then the structural design and safety analysis are carried out, and the durability design and analysis of the structural components are conducted. With the consideration of the mechanical performance, construction convenience and life-cycle cost, the structural scheme for bridges using twin-I girders, cross beams and precast full-width deck is recommended. Weather resistant steel is recommended to be used in nonmarine seasonal freezing regions with stabilization treatment, waterproof and drainage design, local anti-corrosion coating. Finally, a design process considering material, protective layer thickness and construction control is proposed to improve concrete deck durability.</p>