Probability-based durability design and performance-based concrete quality control of a concrete harbor structure

2008 ◽  
pp. 691-696
Author(s):  
O Gj√∏rv ◽  
V √Örskog
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Wendell Jones ◽  
Binsheng Gong ◽  
Natalia Novoradovskaya ◽  
Dan Li ◽  
Rebecca Kusko ◽  
...  

Abstract Background Oncopanel genomic testing, which identifies important somatic variants, is increasingly common in medical practice and especially in clinical trials. Currently, there is a paucity of reliable genomic reference samples having a suitably large number of pre-identified variants for properly assessing oncopanel assay analytical quality and performance. The FDA-led Sequencing and Quality Control Phase 2 (SEQC2) consortium analyze ten diverse cancer cell lines individually and their pool, termed Sample A, to develop a reference sample with suitably large numbers of coding positions with known (variant) positives and negatives for properly evaluating oncopanel analytical performance. Results In reference Sample A, we identify more than 40,000 variants down to 1% allele frequency with more than 25,000 variants having less than 20% allele frequency with 1653 variants in COSMIC-related genes. This is 5–100× more than existing commercially available samples. We also identify an unprecedented number of negative positions in coding regions, allowing statistical rigor in assessing limit-of-detection, sensitivity, and precision. Over 300 loci are randomly selected and independently verified via droplet digital PCR with 100% concordance. Agilent normal reference Sample B can be admixed with Sample A to create new samples with a similar number of known variants at much lower allele frequency than what exists in Sample A natively, including known variants having allele frequency of 0.02%, a range suitable for assessing liquid biopsy panels. Conclusion These new reference samples and their admixtures provide superior capability for performing oncopanel quality control, analytical accuracy, and validation for small to large oncopanels and liquid biopsy assays.


2013 ◽  
Vol 838-841 ◽  
pp. 30-35
Author(s):  
Xiao Bin Sun ◽  
Tian Ling Du ◽  
Bo Tian

With regards to the quality problem of concrete that cant be found out earlier in the quality control, this paper discussed the principle to rapidly detect composition of concrete mixture and analyzed the measurement accuracy of water checker for fresh concrete through laboratory test. Experiments showed that the error in unit cement and unit water measured by instruments is relatively small and able to meet the accuracy requirements. And, the application of rapid detection techniques to the concrete quality control in practical engineering has achieved good results.


2018 ◽  
Vol 768 ◽  
pp. 306-313 ◽  
Author(s):  
Chun Zhi Zhao ◽  
Yi Liu ◽  
Shi Wei Ren ◽  
Jiang Quan

Concrete is the most extensively used material in building and civil project structure. With the rapid development of economic construction, urban construction and infrastructure construction increase year by year, so there is a greater demand for concrete, which brings the rapid development of ready-mixed concrete industry. During the rapid development, structural safety and durability problems caused by concrete quality appear frequently. Meanwhile, to implement the fundamental national policies of resource conservation and environment protection, according to Green Building Action Plan (GUOBANFA [2013] No.1) approved by CPC Central Committee and the State Council, besides meeting the quality requirements, ready-mixed concrete must also meet the green products requirements of "energy conservation, emission reduction, safety, convenience and recyclability" for the vigorous development of green building material and supporting the requirements for building energy conservation, green building and new-type urbanization construction. By quality testing, this paper elaborates the green assessment technology for ready-mixed concrete in combination with raw material quality control, design of mix ratio, production process quality control, construction process quality control, residual concrete treatment, hardened concrete quality control, and control of dust, noise and wastewater. The greening of ready-mixed concrete brings the production and application of green building material, promotes the transformation and upgrading of building material industry and drives the development of green building.


2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Sheng Hu ◽  
Shuanjun Song ◽  
Wenhui Liu

Considering the problem that the process quality state is difficult to analyze and monitor under manufacturing big data, this paper proposed a data cloud model similarity-based quality fluctuation monitoring method in data-driven production process. Firstly, the randomness of state fluctuation is characterized by entropy and hyperentropy features. Then, the cloud pool drive model between quality fluctuation monitoring parameters is built. On this basis, cloud model similarity degree from the perspective of maximum fluctuation border is defined and calculated to realize the process state analysis and monitoring. Finally, the experiment is conducted to verify the adaptability and performance of the cloud model similarity-based quality control approach, and the results indicate that the proposed approach is a feasible and acceptable method to solve the process fluctuation monitoring and quality stability analysis in the production process.


Author(s):  
K G Swift ◽  
A J Allen

The design of a product largely predetermines its cost and quality, and there are therefore limits to the benefits that can be obtained by the application of best practice in manufacturing and quality control. The paper introduces a general model of design for quality and describes a systematic quality evaluation methodology to aid the development of quality competitive products. The application and performance of the methodology are described and its integration with techniques in design for manufacture and assembly is discussed.


Author(s):  
Bach Duong

Unexpected defects of concrete in a completed bored pile can arise during the construction stage. Therefore, post-construction testing of bored pile concrete is an important part of the design and construction process. The Cross-hole Sonic Logging (CSL) method has been the most widely used to examine the concrete quality. This method requires some access tubes pre-installed inside bored piles prior to concreting; the required quantity of access tubes has been pointed out in few literatures and also ruled in the national standard of Vietnam (TCVN 9395:2012). However, theoretical bases aiming to decide the required quantity of access tubes have not been given yet. A probability approach is proposed in this paper aiming to determine the essential quantity of access tubes, which depend not only on pile diameters, magnitude of defects, but also on the technical characteristics of CSL equipment. Keywords: access tubes; bored piles; CSL method; defects; inspection probability.


2017 ◽  
Vol 5 (1) ◽  
pp. 35-42
Author(s):  
LIa Alfa Rosida ◽  
Sudiro Sudiro

The indicator achievement of minimum service standard (MSS) for the accuracy of distributingdrugs in Pharmacy Unit of Keluarga Sehat Hospital has not been achieved, even the incidence ofthe distributionerror from 2013 to 2016 continues to increase. The purpose of this researchwas to analyze the quality control process in the implementation of MSS in Pharmacy Unit of Keluarga Sehat Hospital. This was a qualitative research, with research subject 3pharmacy officers and 3 people of pharmacy management services.Data collectedby in-depth interview and observation of pharmaceutical performance report data and analysed by content analysis. The result of the research showed that the evaluation of pharmacy staff performance has not been implemented, because there is no performance appraisal indicator yet. Comparison was done only by comparing reports with general target, medical support manager double job resulted in no feedback to Pharmacy Unit, and so it has not supported the implementation of MSS. The Improvement of performancehas not been implementedand has notfound the concept of improvement. The new management will attempt to conduct a comparative study, including pharmacy installation into the Quality Control Group (GKM) or Problem Solving for Better Health (PSBH), find the cause of the problem and develop the policy. It can be concluded that the quality control of the MSS in the Pharmacy Unit still not going well and need to be improved especially related to quality performance appraisal and performance improvement based on the SOP.


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