Progress Toward Deep Sequencing-Based Discovery of Stress-Related MicroRNA in Plants and Available Bioinformatics Tools

2018 ◽  
pp. 41-76 ◽  
Author(s):  
Abdelali Hannoufa ◽  
Craig Matthews ◽  
Biruk A. Feyissa ◽  
Margaret Y. Gruber ◽  
Muhammad Arshad
Keyword(s):  
Deep Sequencing ◽  
Bioinformatics Tools

Quasispecies Pattern of Hepatitis B Virus Predicts Hepatocellular Carcinoma Using Deep-Sequencing and Machine Learning

2020 ◽  
Author(s):  
Shipeng Chen ◽  
Zihan Zhang ◽  
Ying Wang ◽  
Meng Fang ◽  
Jun Zhou ◽  
...  
Keyword(s):  
Machine Learning ◽  
Hepatocellular Carcinoma ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Deep Sequencing ◽  
B Virus

Integrating Bioinformatics Strategies in Cancer Immunotherapy: Current and Future Perspectives

2020 ◽  
Vol 23 (8) ◽  
pp. 687-698 ◽  
Author(s):  
Houda N. Washah ◽  
Elliasu Y. Salifu ◽  
Opeyemi Soremekun ◽  
Ahmed A. Elrashedy ◽  
Geraldene Munsamy ◽  
...  
Keyword(s):  
Cancer Immunotherapy ◽  
Therapeutic Potential ◽  
Cell Cancer ◽  
Full Potential ◽  
Future Perspectives ◽  
The Past ◽  
Bioinformatics Tools ◽  
Treatment Paradigm ◽  
Immunotherapy Of Cancer ◽  
Significant Attention

For the past few decades, the mechanisms of immune responses to cancer have been exploited extensively and significant attention has been given into utilizing the therapeutic potential of the immune system. Cancer immunotherapy has been established as a promising innovative treatment for many forms of cancer. Immunotherapy has gained its prominence through various strategies, including cancer vaccines, monoclonal antibodies (mAbs), adoptive T cell cancer therapy, and immune checkpoint therapy. However, the full potential of cancer immunotherapy is yet to be attained. Recent studies have identified the use of bioinformatics tools as a viable option to help transform the treatment paradigm of several tumors by providing a therapeutically efficient method of cataloging, predicting and selecting immunotherapeutic targets, which are known bottlenecks in the application of immunotherapy. Herein, we gave an insightful overview of the types of immunotherapy techniques used currently, their mechanisms of action, and discussed some bioinformatics tools and databases applied in the immunotherapy of cancer. This review also provides some future perspectives in the use of bioinformatics tools for immunotherapy.

scholarly journals Rare Variants Imputation in Admixed Populations: Comparison Across Reference Panels and Bioinformatics Tools

2019 ◽  
Vol 10 ◽  
Author(s):  
Sanjeev Sariya ◽  
Joseph H. Lee ◽  
Richard Mayeux ◽  
Badri N. Vardarajan ◽  
Dolly Reyes-Dumeyer ◽  
...  
Keyword(s):  
Rare Variants ◽  
Bioinformatics Tools
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