scholarly journals A computer model of intracranial pressure dynamics during traumatic brain injury that explicitly models fluid flows and volumes

2006 ◽  
pp. 321-326 ◽  
Author(s):  
W. Wakeland ◽  
B. Goldstein
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Intracranial Pressure ◽  
Computer Model ◽  
Fluid Flows ◽  
Pressure Dynamics

Systemic Hyperthermia in Traumatic Brain Injury—Relation to Intracranial Pressure Dynamics, Cerebral Energy Metabolism, and Clinical Outcome

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Teodor M. Svedung Wettervik ◽  
Henrik Engquist ◽  
Samuel Lenell ◽  
Timothy Howells ◽  
Lars Hillered ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Energy Metabolism ◽  
Intracranial Pressure ◽  
Clinical Outcome ◽  
Cerebral Energy Metabolism ◽  
Pressure Dynamics

scholarly journals Ketamine in acute phase of severe traumatic brain injury “an old drug for new uses?”

Critical Care ◽  
2021 ◽  
Vol 25 (1) ◽  
Author(s):  
Daniel Agustin Godoy ◽  
Rafael Badenes ◽  
Paolo Pelosi ◽  
Chiara Robba
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Intracranial Pressure ◽  
Acute Phase ◽  
Severe Traumatic Brain Injury ◽  
Safety Profile ◽  
Point Of View ◽  
Current Evidence ◽  
Potential Benefits ◽  
Sedation And Analgesia

AbstractMaintaining an adequate level of sedation and analgesia plays a key role in the management of traumatic brain injury (TBI). To date, it is unclear which drug or combination of drugs is most effective in achieving these goals. Ketamine is an agent with attractive pharmacological and pharmacokinetics characteristics. Current evidence shows that ketamine does not increase and may instead decrease intracranial pressure, and its safety profile makes it a reliable tool in the prehospital environment. In this point of view, we discuss different aspects of the use of ketamine in the acute phase of TBI, with its potential benefits and pitfalls.

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