Dopamine D1 and Glutamate N-Methyl-D-Aspartate Receptors: An Essential Interplay in Prefrontal Cortex Synaptic Plasticity

2007 ◽  
pp. 153-164
Author(s):  
María Sol Kruse ◽  
Thérèse M. Jay
Keyword(s):  
Prefrontal Cortex ◽  
Synaptic Plasticity

Differential expression of molecular markers of synaptic plasticity in the hippocampus, prefrontal cortex, and amygdala in response to spatial learning, predator exposure, and stress-induced amnesia

Hippocampus ◽  
2011 ◽  
Vol 22 (3) ◽  
pp. 577-589 ◽  
Author(s):  
Phillip R. Zoladz ◽  
Collin R. Park ◽  
Joshua D. Halonen ◽  
Samina Salim ◽  
Karem H. Alzoubi ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Molecular Markers ◽  
Synaptic Plasticity ◽  
Differential Expression ◽  
Spatial Learning

Inactivation of BRD7 results in impaired cognitive behavior and reduced synaptic plasticity of the medial prefrontal cortex

2015 ◽  
Vol 286 ◽  
pp. 1-10 ◽  
Author(s):  
Yang Xu ◽  
Wenyu Cao ◽  
Ming Zhou ◽  
Changqi Li ◽  
Yanwei Luo ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Synaptic Plasticity ◽  
Medial Prefrontal Cortex ◽  
Cognitive Behavior

Repeated transcranial direct current stimulation improves cognitive dysfunction and synaptic plasticity deficit in the prefrontal cortex of streptozotocin-induced diabetic rats

2017 ◽  
Vol 10 (6) ◽  
pp. 1079-1087 ◽  
Author(s):  
Yi-Jen Wu ◽  
Chou-Ching Lin ◽  
Che-Ming Yeh ◽  
Miao-Er Chien ◽  
Ming-Chung Tsao ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Synaptic Plasticity ◽  
Cognitive Dysfunction ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Diabetic Rats ◽  
Direct Current Stimulation

scholarly journals Synapse Plasticity in Motor, Sensory, and Limbo-Prefrontal Cortex Areas as Measured by Degrading Axon Terminals in an Environment Model of Gerbils (Meriones unguiculatus)

2009 ◽  
Vol 2009 ◽  
pp. 1-14 ◽  
Author(s):  
Janina Neufeld ◽  
Gertraud Teuchert-Noodt ◽  
Keren Grafen ◽  
York Winter ◽  
A. Veronica Witte
Keyword(s):  
Prefrontal Cortex ◽  
Synaptic Plasticity ◽  
Meriones Unguiculatus ◽  
Secondary Lysosome ◽  
Axon Terminals ◽  
Environment Model ◽  
Naturally Occurring ◽  
Synapse Plasticity ◽  
Map Adaptation ◽  
Cortical Map

Still little is known about naturally occurring synaptogenesis in the adult neocortex and related impacts of epigenetic influences. We therefore investigated (pre)synaptic plasticity in various cortices of adult rodents, visualized by secondary lysosome accumulations (LA) in remodeling axon terminals. Twenty-two male gerbils from either enriched (ER) or impoverished rearing (IR) were used for quantification of silver-stained LA. ER-animals showed rather low LA densities in most primary fields, whereas barrel and secondary/associative cortices exhibited higher densities and layer-specific differences. In IR-animals, these differences were evened out or even inverted. Basic plastic capacities might be linked with remodeling of local intrinsic circuits in the context of cortical map adaptation in both IR- and ER-animals. Frequently described disturbances due to IR in multiple corticocortical and extracortical afferent systems, including the mesocortical dopamine projection, might have led to maladaptations in the plastic capacities of prefronto-limbic areas, as indicated by different LA densities in IR- compared with ER-animals.

Interleukin 6 Dependent Synaptic Plasticity in a Social Defeat-Susceptible Prefrontal Cortex Circuit

Neuroscience ◽  
2019 ◽  
Vol 414 ◽  
pp. 280-296
Author(s):  
Eric Esquivel-Rendón ◽  
Jorge Vargas-Mireles ◽  
Roberto Cuevas-Olguín ◽  
Marcela Miranda-Morales ◽  
Palmira Acosta-Mares ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Synaptic Plasticity ◽  
Interleukin 6 ◽  
Social Defeat

scholarly journals Genetic evidence for the bidirectional modulation of synaptic plasticity in the prefrontal cortex by D1 receptors

2004 ◽  
Vol 101 (9) ◽  
pp. 3236-3241 ◽  
Author(s):  
Y.-Y. Huang ◽  
E. Simpson ◽  
C. Kellendonk ◽  
E. R. Kandel
Keyword(s):  
Prefrontal Cortex ◽  
Synaptic Plasticity ◽  
Genetic Evidence ◽  
D1 Receptors ◽  
Bidirectional Modulation

scholarly journals Quinolinic acid injection in mouse medial prefrontal cortex affects reversal learning abilities, cortical connectivity and hippocampal synaptic plasticity

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Amira Latif-Hernandez ◽  
Disha Shah ◽  
Tariq Ahmed ◽  
Adrian C. Lo ◽  
Zsuzsanna Callaerts-Vegh ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Synaptic Plasticity ◽  
Medial Prefrontal Cortex ◽  
Reversal Learning ◽  
Quinolinic Acid ◽  
Cortical Connectivity ◽  
Learning Abilities ◽  
Hippocampal Synaptic Plasticity ◽  
Acid Injection

scholarly journals Medial Prefrontal Cortex Inversely Regulates Toluene-Induced Changes in Markers of Synaptic Plasticity of Mesolimbic Dopamine Neurons

2013 ◽  
Vol 33 (2) ◽  
pp. 804-813 ◽  
Author(s):  
J. T. Beckley ◽  
C. E. Evins ◽  
H. Fedarovich ◽  
M. J. Gilstrap ◽  
J. J. Woodward
Keyword(s):  
Prefrontal Cortex ◽  
Synaptic Plasticity ◽  
Medial Prefrontal Cortex ◽  
Dopamine Neurons ◽  
Mesolimbic Dopamine ◽  
Induced Changes

Decreased synaptic plasticity in the medial prefrontal cortex underlies short-term memory deficits in 6-OHDA-lesioned rats

2016 ◽  
Vol 301 ◽  
pp. 43-54 ◽  
Author(s):  
Filipe C. Matheus ◽  
Daniel Rial ◽  
Joana I. Real ◽  
Cristina Lemos ◽  
Juliana Ben ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Synaptic Plasticity ◽  
Medial Prefrontal Cortex ◽  
Short Term Memory ◽  
Memory Deficits ◽  
Short Term ◽  
Term Memory
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