High-Grade Salivary Gland Tumors: Salivary Duct Carcinoma, High-Grade Mucoepidermoid Carcinoma, and Carcinoma ex Pleomorphic Adenoma

2008 ◽  
pp. 183-201
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Mucoepidermoid Carcinoma ◽  
Salivary Gland Tumors ◽  
Salivary Duct Carcinoma ◽  
Carcinoma Ex Pleomorphic Adenoma ◽  
High Grade ◽  
Salivary Duct ◽  
Duct Carcinoma

Immunohistochemical expression of mammaglobin in salivary duct carcinomas de novo and salivary duct carcinoma ex pleomorphic adenoma

2019 ◽  
Vol 92 ◽  
pp. 59-66 ◽  
Author(s):  
Ciro Dantas Soares ◽  
Thayná Melo de Lima Morais ◽  
Roman Carlos ◽  
Manoela Domingues Martins ◽  
Oslei Paes de Almeida ◽  
...  
Keyword(s):  
Pleomorphic Adenoma ◽  
De Novo ◽  
Salivary Duct Carcinoma ◽  
Carcinoma Ex Pleomorphic Adenoma ◽  
Immunohistochemical Expression ◽  
Salivary Duct ◽  
Duct Carcinoma

Combined salivary duct carcinoma and squamous cell carcinoma suspected of carcinoma ex pleomorphic adenoma

2016 ◽  
Vol 66 (8) ◽  
pp. 460-465 ◽  
Author(s):  
Tomohiro Enokida ◽  
Satoshi Fujii ◽  
Hirofumi Kuno ◽  
Takashi Mukaigawa ◽  
Makoto Tahara ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Pleomorphic Adenoma ◽  
Squamous Cell ◽  
Salivary Duct Carcinoma ◽  
Carcinoma Ex Pleomorphic Adenoma ◽  
Salivary Duct ◽  
Duct Carcinoma

Salivary duct carcinoma and the concept of early carcinoma ex pleomorphic adenoma

2014 ◽  
Vol 65 (6) ◽  
pp. 854-860 ◽  
Author(s):  
Christopher C Griffith ◽  
Lester D R Thompson ◽  
Adel Assaad ◽  
Bibianna M Purgina ◽  
Chi Lai ◽  
...  
Keyword(s):  
Pleomorphic Adenoma ◽  
Early Carcinoma ◽  
Salivary Duct Carcinoma ◽  
Carcinoma Ex Pleomorphic Adenoma ◽  
Salivary Duct ◽  
Duct Carcinoma

scholarly journals Histopathological Pattern of Salivary Gland Tumors

2014 ◽  
Vol 4 (7) ◽  
pp. 520-524 ◽  
Author(s):  
S Shrestha ◽  
GK Pandey ◽  
CB Pun ◽  
R Bhatta ◽  
R Shahi
Keyword(s):  
Salivary Gland ◽  
Salivary Glands ◽  
Pleomorphic Adenoma ◽  
Malignant Tumor ◽  
Mucoepidermoid Carcinoma ◽  
Salivary Gland Tumor ◽  
Salivary Gland Tumors ◽  
Carcinoma Ex Pleomorphic Adenoma ◽  
Common Site ◽  
Gland Tumor

Background: The tumors of the salivary glands are uncommon head and neck neoplasms. The aim of this study was to evaluate the relative frequencies, types, site distribution and the histopathological features of salivary gland tumors. Materials and Methods: This was a retrospective study of 176 cases of salivary gland tumors collected from medical record section and department of pathology at B.P.Koirala Memorial Cancer Hospital from Jan. 2005 to Dec. 2010. Tumors were analyzed based on demographics, anatomic location and histopathological type. Results: Out of 176 cases, 66 (37.5 %) were benign and 110 (62.5 %) were malignant with M:F ratio of 1.7:1. The mean age observed was 44.76 years with age range of 12 to 75 years. Pleomorphic adenoma was found to be the commonest benign tumor (72.7 %), followed by Warthin tumor (15.1%), monomorphic adenoma (3.0 %) and basal cell adenoma (3.0 %). The mucoepidermoid carcinoma was the most common malignant tumor (38.1 %), followed by adenoid cystic carcinoma (25.4%), acinic cell carcinoma (10.9%), adenocarcinoma NOS (6.3%), carcinoma ex pleomorphic adenoma (5.4%) and unclassified malignant tumor (4.5 %). Parotid was the most common site for the location of tumors (70.4%) followed by submandibular (19.3%) and minor salivary glands (10.2 %). Conclusion: Pleomorphic adenoma was the commonest salivary gland tumor observed in both sexes. Mucoepidermoid carcinoma was the most common malignant salivary gland tumor. The parotid gland was the most common site of origin in both benign and malignant tumors. DOI: http://dx.doi.org/10.3126/jpn.v4i7.10291 Journal of Pathology of Nepal (2014) Vol. 4, 520-524

scholarly journals Cytologic features of saromatoid salivary duct carcinoma ex pleomorphic adenoma of the parotid gland.

1998 ◽  
Vol 37 (3) ◽  
pp. 328-332
Author(s):  
Naoko YAMADA ◽  
Kouichi NOMURA ◽  
Keizo TAKAGI ◽  
Yasuo ONO ◽  
Takashi HOMMA ◽  
...  
Keyword(s):  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
Salivary Duct Carcinoma ◽  
Carcinoma Ex Pleomorphic Adenoma ◽  
Salivary Duct ◽  
Duct Carcinoma

Carcinoma Ex Pleomorphic Adenoma of the Palate Composed of Invasive Micropapillary Salivary Duct Carcinoma and Adenoid Cystic Carcinoma Components: An Unusual Case

2015 ◽  
Vol 120 (2) ◽  
pp. e49-e50
Author(s):  
BRUNO TAVARES SEDASSARI ◽  
NELISE ALEXANDRE DA SILVA LASCANE ◽  
PRISCILA LIE TOBOUTI ◽  
MARIA ISETE FARES FRANCO ◽  
SUZANA CANTANHEDE ORSINI MACHADO DE SOUSA
Keyword(s):  
Adenoid Cystic Carcinoma ◽  
Pleomorphic Adenoma ◽  
Unusual Case ◽  
Salivary Duct Carcinoma ◽  
Carcinoma Ex Pleomorphic Adenoma ◽  
Salivary Duct ◽  
Duct Carcinoma ◽  
Adenoid Cystic

scholarly journals Primary and Secondary/ Metastatic Salivary Duct Carcinoma Presenting within the Sinonasal Tract

2021 ◽  
Author(s):  
Abbas Agaimy ◽  
Sarina K. Mueller ◽  
Justin A. Bishop ◽  
Simion I. Chiosea
Keyword(s):  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
Case Series ◽  
Sinonasal Tract ◽  
Salivary Duct Carcinoma ◽  
High Grade ◽  
Salivary Duct ◽  
Duct Carcinoma ◽  
Primary Tumors ◽  
Secondary Tumors

AbstractTraditionally, sinonasal adenocarcinomas have been subdivided into intestinal (ITAC) and non-intestinal (non-ITAC) categories. The latter encompasses salivary-type adenocarcinomas originating from the seromucinous glands of the sinonasal mucosa and non-salivary adenocarcinomas. The non-salivary adenocarcinoma category is further subdivided into low-and high-grade variants. Among salivary-type sinonasal adenocarcinomas, tumors recapitulating salivary duct carcinoma (SDC) are exceedingly rare, but some might have been lumped into the high-grade non-ITAC category. To date, only three primary SDCs originating in the sinonasal tract have been reported. We herein describe 7 cases of SDC including one previously reported case (4 primary sinonasal, 3 metastatic/ extension from parotid gland SDC). The primary tumors affected 3 males and one female aged 60 – 75. Different sites were involved by the primary tumors while the secondary tumors affected the sphenoidal (2) and the frontal + maxillary (1) sinuses. Three primary tumors were de novo high-grade SDC and one was confined to contours of a pre-existing pleomorphic adenoma. All 3 secondary tumors were SDC ex pleomorphic adenoma of the parotid with a long history of recurrences, ultimately involving the sinonasal tract. Androgen receptor was positive in 7/7 cases. Four of 6 cases were strongly HER2/neu + (either score 3 + or with verified amplification). This small case series adds to the delineation of primary sinonasal SDC highlighting that almost half of invasive SDC presenting within sinonasal tract indeed represents extension or metastasis from a parotid gland primary. There is a tendency towards overrepresentation of HER2/neu-positive cases in both categories (primary and metastatic), but this needs clarification in larger studies.

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